Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Maximilian Schmutz"'
Autor:
Lena Pigat, Benjamin P Geisler, Seyedmostafa Sheikhalishahi, Julia Sander, Mathias Kaspar, Maximilian Schmutz, Sven Olaf Rohr, Carl Mathis Wild, Sebastian Goss, Sarra Zaghdoudi, Ludwig Christian Hinske
Publikováno v:
JMIR Medical Informatics, Vol 12, Pp e50642-e50642 (2024)
Abstract BackgroundHypoxia is an important risk factor and indicator for the declining health of inpatients. Predicting future hypoxic events using machine learning is a prospective area of study to facilitate time-critical interventions to counter
Externí odkaz:
https://doaj.org/article/26bc293d47114791957091fc3e6f0d3e
Autor:
Maximilian Schmutz, Manuela Zucknick, Richard F. Schlenk, Daniel Mertens, Axel Benner, Dieter Weichenhan, Oliver Mücke, Konstanze Döhner, Christoph Plass, Lars Bullinger, Rainer Claus
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-16 (2023)
Abstract Background Acute myeloid leukemia (AML) is a heterogeneous disease with a poor prognosis. Dysregulation of the epigenetic machinery is a significant contributor to disease development. Some AML patients benefit from treatment with hypomethyl
Externí odkaz:
https://doaj.org/article/97807982449d429dbc05a64bad75bfbb
Autor:
Sebastian Sommer, Maximilian Schmutz, Tina Schaller, Patrick Mayr, Sebastian Dintner, Bruno Märkl, Ralf Huss, M. Monika Golas, Michaela Kuhlen, Frank Jordan, Rainer Claus, Bernhard Heinrich
Publikováno v:
Cancer Reports, Vol 7, Iss 1, Pp n/a-n/a (2024)
Abstract Background Inflammatory myofibroblastic tumor (IMTs) are rare mesenchymal neoplasms with slow growth. Resection is considered as therapeutic standard, with chemotherapy being insufficiently effective in advanced disease. ALK translocations a
Externí odkaz:
https://doaj.org/article/5e11ff40774f49958e3d8ec99b37fc04
Autor:
Patrick Mayr, Mathias Lutz, Maximilian Schmutz, Jens Hoeppner, Friederike Liesche-Starnecker, Jürgen Schlegel, Jochen Gaedcke, Rainer Claus
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundJC virus reactivation causing progressive multifocal leukoencephalopathy (PML) occurs preferentially in human immunodeficiency virus (HIV) positive individuals or patients suffering from hematologic neoplasms due to impaired viral control.
Externí odkaz:
https://doaj.org/article/c9b16a50fc2b4701baac0bfad51eb003
Autor:
James S. Blachly, Anna Reister Schultz, Maximilian Schmutz, Christopher C. Oakes, Brian J. Druker, Bethany L. Mundy-Bosse, Min Wang, Sebastian Vosberg, Ramiro Garzon, Lars Bullinger, Philipp A. Greif, Ann-Kathrin Eisfeld, Rainer Claus, John C. Byrd, Clara D. Bloomfield, Yue Zhong Wu, Kevin R. Coombes, Brian Giacopelli, Ada C Cleary, Jeffrey W. Tyner
Publikováno v:
Genome Res
Genome Res. 31, 747-761 (2021)
Genome Res. 31, 747-761 (2021)
Acute myeloid leukemia (AML) is a molecularly complex disease characterized by heterogeneous tumor genetic profiles and involving numerous pathogenic mechanisms and pathways. Integration of molecular data types across multiple patient cohorts may adv
Autor:
Maximilian Schmutz, Sebastian Sommer
Publikováno v:
Kompass Onkologie. 8:77-79
Purpose: In previous analyses of the MURANO study, fixed-duration venetoclax plus rituximab (VenR) resulted in improved progression-free survival (PFS) compared with bendamustine plus rituximab (BR) in patients with relapsed or refractory chronic lym
Publikováno v:
TumorDiagnostik & Therapie. 40:29-36
Autor:
Harald Binder, Lars Bullinger, Christoph Plass, Jochen Knaus, Martin Schumacher, Michael Lübbert, Konstanze Döhner, Pascal Schlosser, Maximilian Schmutz, Rainer Claus
Background: State-of-the art selection methods fail to identify weak but cumulative effects of features found in many high-dimensional omics datasets. Nevertheless, these features play an important role in certain diseases. Results: We present Netboo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c74e2fd099ffd4daa1efa2849b97b67
https://opus.bibliothek.uni-augsburg.de/opus4/files/89156/Netboost_Boosting-Supported_Network_Analysis.pdf
https://opus.bibliothek.uni-augsburg.de/opus4/files/89156/Netboost_Boosting-Supported_Network_Analysis.pdf
Autor:
Rainer Claus, Maximilian Schmutz
Publikováno v:
Kompass Onkologie. 6:210-212
Hintergrund: 4-7% der Patienten mit metastasierten Adenokarzinomen des Pankreas weisen Keimbahnmutationen in den für die DNA-Reparatur wichtigen Genen BRCA1 oder BRCA2 auf. Inhibitoren der Poly(ADP-Ribose)Polymerase (PARP) wie z.B. Olaparib (Lynparz
Autor:
Bruno Märkl, Martin Trepel, Klaus Hirschbühl, S Dintner, B Kubuschok, T Häckel, C Fleischmann, Tina Schaller, Rainer Claus, Maximilian Schmutz
Ein 35-jahriger Patient mit periodischem Fieber bis 40 °C, Halsschmerzen, Myalgie und Zephalgien stellte sich zur Abklarung einer Panzytopenie vor. Die Umfeld- und jungere Reiseanamnese waren, abgesehen von einem Besuch in Italien vor einem Jahr und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b4bf8b3545c8bb4a98f7b0096d0cda7
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/72225
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/72225