Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Maximilian Nastaly"'
Autor:
Gábor Zsurka, Maximilian L. T. Appel, Maximilian Nastaly, Kerstin Hallmann, Niels Hansen, Daniel Nass, Tobias Baumgartner, Rainer Surges, Gunther Hartmann, Eva Bartok, Wolfram S. Kunz
Publikováno v:
Cells, Vol 12, Iss 2, p 227 (2023)
Epilepsy and mental retardation are known to be associated with pathogenic mutations in a broad range of genes that are expressed in the brain and have a role in neurodevelopment. Here, we report on a family with three affected individuals whose clin
Externí odkaz:
https://doaj.org/article/e1a5d280b4af451aa6c445979dd7f621
Autor:
Christoph Coch, Benjamin Hommertgen, Thomas Zillinger, Juliane Daßler-Plenker, Bastian Putschli, Maximilian Nastaly, Beate M. Kümmerer, Johanna F. Scheunemann, Beatrix Schumak, Sabine Specht, Martin Schlee, Winfried Barchet, Achim Hoerauf, Eva Bartok, Gunther Hartmann
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
During blood-stage malaria, the innate immune system initiates the production of pro-inflammatory cytokines, including IFN-γ, that are critical to host defense and responsible for severe disease. Nonetheless, the innate immune pathways activated dur
Externí odkaz:
https://doaj.org/article/02c8566af8ae41498b09c31bd0928bb9
Autor:
Eva Sarah Bartok, Thomas Ostendorf, Thomas Zillinger, Katarzyna Andryka, Thais Marina Guimaraes, Saskia Schmitz, Samira Marx, Kübra Bayrak, Rebecca Linke, Sarah Salgert, Tatjana Grasser, Sonja Baersachs, Marc Hübner, Leon Soltesz, Matthias Kettwig, Maximilian Nastaly, Ingo Roehl, Marco Henneke, Winfried Barchet, Jutta Gärtner, Martin Schlee, Gunther Hartmann
Publikováno v:
The Journal of Immunology. 204:226.30-226.30
Human TLR8 is an essential sensor of bacterial RNA which induces proinflammatory and Th1 cytokines. Crystallography revealed that TLR8 binds both uridine and short single-stranded RNA, but the RNases that process the RNA are still unknown. Herein, we
Autor:
Thomas Ostendorf, Christoph Coch, Maximilian Nastaly, Saskia Schmitz, Leon Soltesz, Tatjana Grasser, Thomas Zillinger, Samira Marx, Julia Wegner, Rebecca Linke, Achim Hoerauf, Eva Bartok, Sonja Bauersachs, Marc P. Hübner, Matthias Kettwig, Winfried Barchet, Marco Henneke, Thais Marina Schlee-Guimaraes, Sarah Salgert, Martin Schlee, Jutta Gärtner, Gunther Hartmann, Katarzyna Andryka, Kübra Bayrak, Ingo Roehl
Publikováno v:
Immunity. 52:591-605.e6
Summary Human toll-like receptor 8 (TLR8) activation induces a potent T helper-1 (Th1) cell response critical for defense against intracellular pathogens, including protozoa. The receptor harbors two distinct binding sites, uridine and di- and/or tri
Autor:
Christoph, Coch, Benjamin, Hommertgen, Thomas, Zillinger, Juliane, Daßler-Plenker, Bastian, Putschli, Maximilian, Nastaly, Beate M, Kümmerer, Johanna F, Scheunemann, Beatrix, Schumak, Sabine, Specht, Martin, Schlee, Winfried, Barchet, Achim, Hoerauf, Eva, Bartok, Gunther, Hartmann
Publikováno v:
Frontiers in Immunology
During blood-stage malaria, the innate immune system initiates the production of pro-inflammatory cytokines, including IFN-γ, that are critical to host defense and responsible for severe disease. Nonetheless, the innate immune pathways activated dur