Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Maximilian Kießler"'
Autor:
Luise Rupp, Ina Dietsche, Maximilian Kießler, Ulrich Sommer, Alexander Muckenhuber, Katja Steiger, Casper W. F. van Eijck, Leonard Richter, Rouzanna Istvanffy, Carsten Jäger, Helmut Friess, Casper H. J. van Eijck, Ihsan Ekin Demir, Carmen Mota Reyes, Marc Schmitz
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Pancreatic ductal adenocarcinoma (PDAC) is typically diagnosed at advanced stages and associated with early distant metastasis and poor survival. Besides clinical factors, the tumor microenvironment (TME) emerged as a crucial determinant of patient s
Externí odkaz:
https://doaj.org/article/060c11c0f0df4fe48ce6b5de61634e0a
Autor:
Xiaobo Wang, Rouzanna Istvanffy, Linhan Ye, Steffen Teller, Melanie Laschinger, Kalliope N. Diakopoulos, Kıvanç Görgülü, Qiaolin Li, Lei Ren, Carsten Jäger, Katja Steiger, Alexander Muckenhuber, Baiba Vilne, Kaan Çifcibaşı, Carmen Mota Reyes, Ümmügülsüm Yurteri, Maximilian Kießler, Ibrahim Halil Gürçınar, Maya Sugden, Saliha Elif Yıldızhan, Osman Uğur Sezerman, Sümeyye Çilingir, Güldal Süyen, Maximilian Reichert, Roland M. Schmid, Stefanie Bärthel, Rupert Oellinger, Achim Krüger, Roland Rad, Dieter Saur, Hana Algül, Helmut Friess, Marina Lesina, Güralp Onur Ceyhan, Ihsan Ekin Demir
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 21 (2023)
Solid cancers like pancreatic ductal adenocarcinoma (PDAC), a type of pancreatic cancer, frequently exploit nerves for rapid dissemination. This neural invasion (NI) is an independent prognostic factor in PDAC, but insufficiently modeled in genetical
Externí odkaz:
https://doaj.org/article/de6bfa94aa5043158c58f7d898718cfc
Autor:
Lei Ren, MD, Carsten Jäger, MPH, Stephan Schorn, Ilaria Pergolini, Rüdiger Göß, Okan Safak, Maximilian Kießler, Marc E. Martignoni, Alexander R. Novotny, Helmut Friess, Güralp O. Ceyhan, Ihsan Ekin Demir
Publikováno v:
Annals of Surgery Open, Vol 4, Iss 3, p e302 (2023)
Background:. Arterial resection (AR) during pancreatectomy for curative R0 resection of pancreatic ductal adenocarcinoma (PDAC) remains a controversial procedure with high morbidity. Objective:. To investigate the feasibility and oncological outcomes
Externí odkaz:
https://doaj.org/article/a0a7376ec8a24c4fa86e22a8b7ac848b
Autor:
Hans-Georg Rammensee, Karl-Heinz Wiesmüller, P. Anoop Chandran, Henning Zelba, Elisa Rusch, Cécile Gouttefangeas, Daniel J. Kowalewski, Moreno Di Marco, Sebastian P. Haen, Juliane S. Walz, Yamel Cardona Gloria, Johanna Bödder, Jill-Marie Schertel, Antje Tunger, Luise Müller, Maximilian Kießler, Rebekka Wehner, Marc Schmitz, Meike Jakobi, Nicole Schneiderhan-Marra, Reinhild Klein, Karoline Laske, Kerstin Artzner, Linus Backert, Heiko Schuster, Johannes Schwenck, Alexander N. R. Weber, Bernd J. Pichler, Manfred Kneilling, Christian la Fougère, Stephan Forchhammer, Gisela Metzler, Jürgen Bauer, Benjamin Weide, Wilfried Schippert, Stefan Stevanović, Markus W. Löffler
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-18 (2019)
Abstract Background We previously showed that the bacterial lipopeptide Pam3Cys-Ser-Ser, meanwhile established as a toll-like receptor (TLR) 1/2 ligand, acts as a strong adjuvant for the induction of virus specific CD8+ T cells in mice, when covalent
Externí odkaz:
https://doaj.org/article/cc3a16412b7c49e5953df66f2cd4dccd
Autor:
Ulrich Sommer, Jürgen Weitz, Daniela Aust, Maximilian Kießler, Ioana Plesca, Rebekka Wehner, Friederike Wilczkowski, Luise Müller, Antje Tunger, Xixi Lai, Anke Rentsch, Adrian M Seifert, Lena Seifert, Michael Bachmann, Martin Bornhäuser, Gustavo Baretton, Marc Schmitz
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Background Plasmacytoid dendritic cells (pDCs) play a key role in the induction and maintenance of antitumor immunity. Conversely, they can act as tolerogenic DCs by inhibiting tumor-directed immune responses. Therefore, pDCs may profoundly influence
Externí odkaz:
https://doaj.org/article/47849b5e9eeb4ac59685008f84a1679c
Autor:
Felix Wagner, Ulrike Hölig, Friederike Wilczkowski, Ioana Plesca, Ulrich Sommer, Rebekka Wehner, Maximilian Kießler, Armin Jarosch, Katharina Flecke, Maia Arsova, Antje Tunger, Andreas Bogner, Christoph Reißfelder, Jürgen Weitz, Knut Schäkel, Esther G. C. Troost, Mechthild Krause, Gunnar Folprecht, Martin Bornhäuser, Michael P. Bachmann, Daniela Aust, Gustavo Baretton, Marc Schmitz
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Neoadjuvant radiochemotherapy (nRCT) can significantly influence the tumor immune architecture that plays a pivotal role in regulating tumor growth. Whereas, various studies have investigated the effect of nRCT on tumor-infiltrating T cells, little i
Externí odkaz:
https://doaj.org/article/030ea4ff884e4213904d09e1d8759f7a
Autor:
Carmen Mota Reyes, Maximilian Kiessler, Pino Bordignon, Samuel Aubert, Pamela Pulimeno, Helmut Friess, Rouzanna Istvanffy, Ihsan Ekin Demir
Publikováno v:
Cancer Research. 83:2254-2254
Pancreatic cancer is one of the most common cancers worldwide and its incidence is increasing globally. Treatment consists of surgical resection followed by adjuvant or neoadjuvant therapy. Neoadjuvant therapy (neoTx) has dramatically improved the pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60111b726d5444fd68daa9d9f703b385
https://doi.org/10.1158/1538-7445.am2023-2254
https://doi.org/10.1158/1538-7445.am2023-2254
Publikováno v:
Information Integration and Web Intelligence ISBN: 9783031210464
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3a012cb2e786038122f1072975da22c
https://doi.org/10.1007/978-3-031-21047-1_26
https://doi.org/10.1007/978-3-031-21047-1_26
Autor:
Antje Tunger, Maximilian Kießler, Rebekka Wehner, Achim Temme, Friedegund Meier, Michael Bachmann, Marc Schmitz
Publikováno v:
Biomedicines, Vol 6, Iss 1, p 26 (2018)
Targeting the immune checkpoint receptors cytotoxic T lymphocyte antigen 4 (CTLA-4), programmed cell death protein 1 (PD-1), or programmed cell death 1 ligand 1 (PD-L1) represents a very attractive treatment modality for tumor patients. The administr
Externí odkaz:
https://doaj.org/article/f6a4e504e5c44dc9b0675d634daffe22
Publikováno v:
Gastro-News. 8:22-24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4150f763d047f2be40df7b27b5290507
https://doi.org/10.1007/s15036-021-2331-z
https://doi.org/10.1007/s15036-021-2331-z