Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Maximilian J, Gerhardt"'
Autor:
Marina Pavlou, Christian Schön, Laurence M Occelli, Axel Rossi, Nadja Meumann, Ryan F Boyd, Joshua T Bartoe, Jakob Siedlecki, Maximilian J Gerhardt, Sabrina Babutzka, Jacqueline Bogedein, Johanna E Wagner, Siegfried G Priglinger, Martin Biel, Simon M Petersen‐Jones, Hildegard Büning, Stylianos Michalakis
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 4, Pp 1-19 (2021)
Abstract Gene therapy using recombinant adeno‐associated virus (rAAV) vectors to treat blinding retinal dystrophies has become clinical reality. Therapeutically impactful targeting of photoreceptors still relies on subretinal vector delivery, which
Externí odkaz:
https://doaj.org/article/8b6c55ffca62471b9aed7b84bf31bc23
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 269 (2023)
The visual process begins with the absorption of photons by photopigments of cone and rod photoreceptors in the retina. In this process, the signal is first amplified by a cyclic guanosine monophosphate (cGMP)-based signaling cascade and then convert
Externí odkaz:
https://doaj.org/article/9d25d2d742f14f57bb0e27379d02a057
Autor:
Maximilian J. Gerhardt, Claudia S. Priglinger, Günther Rudolph, Karsten Hufendiek, Carsten Framme, Herbert Jägle, Daniel J. Salchow, Andreas Anschütz, Stylianos Michalakis, Siegfried G. Priglinger
Publikováno v:
Biomedicines, Vol 11, Iss 1, p 103 (2022)
Leber congenital amaurosis caused by mutations in the RPE65 gene belongs to the most severe early-onset hereditary childhood retinopathies naturally progressing to legal blindness. The novel gene therapy voretigene neparvovec is the first approved ca
Externí odkaz:
https://doaj.org/article/2bc5238ef77c471eaad5bf5208f029c3
Autor:
Vitus Grauvogl, Nikolaus Luft, Niklas Mohr, Matthias Nobl, Maximilian J. Gerhardt, Jakob Siedlecki, Mehdi Shajari, Wolfgang J. Mayer
Publikováno v:
Die Ophthalmologie. 119:1041-1046
Zusammenfassung Einführung Die phototherapeutische Keratektomie gilt heute als etabliertes Therapieverfahren für Patienten, welche unter therapierefraktären genetisch bedingten Hornhautdystrophien oder rezidivierenden Erosiones ohne zugrunde liege
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74b2eb74609a3d6ddde90e5188a5f3d5
https://doi.org/10.1007/s00347-022-01638-y
https://doi.org/10.1007/s00347-022-01638-y
Publikováno v:
Vision Research. 208:108232
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4b050b704b129dee010e13214e3b3f2
https://doi.org/10.1016/j.visres.2023.108232
https://doi.org/10.1016/j.visres.2023.108232
Autor:
Vitus, Grauvogl, Nikolaus, Luft, Niklas, Mohr, Matthias, Nobl, Maximilian J, Gerhardt, Jakob, Siedlecki, Mehdi, Shajari, Wolfgang J, Mayer
Publikováno v:
Die OphthalmologieLiteratur. 119(10)
Phototherapeutic keratectomy (PTK) is an established treatment method for patients suffering from either genetic corneal dystrophy or recurrent corneal erosion (RCE) without underlying basement membrane dystrophy, often caused by trauma.This study ai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dee117cdb49a1be99d6ec107b803cc66
https://pubmed.ncbi.nlm.nih.gov/35499634
https://pubmed.ncbi.nlm.nih.gov/35499634
Autor:
Felix, Hagenau, Maximilian J, Gerhardt, Wolfgang J, Mayer, Martin, Dirisamer, Siegfried S, Priglinger, Nikolaus, Luft
Publikováno v:
Die OphthalmologieLiteratur. 119(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::76bff75b20d40a55cc6ddb66f373ce9e
https://pubmed.ncbi.nlm.nih.gov/33931787
https://pubmed.ncbi.nlm.nih.gov/33931787
Autor:
Maximilian J, Gerhardt, Joseph A, Marsh, Margaux, Morrison, Andrius, Kazlauskas, Arogya, Khadka, Stephan, Rosenkranz, Margaret M, DeAngelis, Magali, Saint-Geniez, Sarah Melissa P, Jacobo
Publikováno v:
Journal of molecular cell biology
J Mol Cell Biol
J Mol Cell Biol
High temperature requirement A1 (HtrA1) belongs to an ancient protein family that is linked to various human disorders. The precise role of exon 1-encoded N-terminal domains and how these influence the biological functions of human HtrA1 remain elusi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80c1ba9f05690c8c15604effe82d3098
https://doi.org/10.1093/jmcb/mjx040
https://doi.org/10.1093/jmcb/mjx040