Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Maximilian Deest"'
Autor:
Jelte Wieting, Madita Vanessa Baumann, Stephanie Deest-Gaubatz, Stefan Bleich, Christian Karl Eberlein, Helge Frieling, Maximilian Deest
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Neurological soft signs (NSS), discrete deficits in motor coordination and sensory integration, have shown promise as markers in autism diagnosis. While motor impairments, partly associated with core behavioral features, are frequently found
Externí odkaz:
https://doaj.org/article/195c0e4638ec45718dbd57d6cb92ce65
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-13 (2023)
Abstract Background DNA sequence variation and altered epigenetic regulation of the oxytocin receptor gene (OXTR) have been implicated in autism and autistic-like behaviors. While previous studies have examined subsegments of OXTR, nanopore Cas9-targ
Externí odkaz:
https://doaj.org/article/13f72d0b624643ec8af8816ee4d69f36
Autor:
Sara Gombert, Kirsten Jahn, Hansi Pathak, Alexandra Burkert, Gunnar Schmidt, Lutz Wiehlmann, Colin Davenport, Björn Brändl, Franz-Josef Müller, Andreas Leffler, Maximilian Deest, Helge Frieling
Publikováno v:
BMC Medical Genomics, Vol 16, Iss 1, Pp 1-12 (2023)
Abstract Background Bisulfite sequencing has long been considered the gold standard for measuring DNA methylation at single CpG resolution. However, in recent years several new approaches like nanopore sequencing have been developed due to hints for
Externí odkaz:
https://doaj.org/article/53f21eb283434c95be1a2218ade84fa6
Autor:
Hannah Heseding, Kirsten Jahn, Björn Brändl, Alexandra Haase, Ian O. Shum, Tim Kohrn, Stefan Bleich, Helge Frieling, Ulrich Martin, Franz-Josef Müller, Stephanie Wunderlich, Maximilian Deest
Publikováno v:
Stem Cell Research, Vol 71, Iss , Pp 103143- (2023)
Prader-Willi syndrome (PWS) is a neurodevelopmental disorder caused by loss of paternal expression of imprinted genes on chromosome 15q11-q13. We established a human induced pluripotent stem cell line (hiPSC), ZIPi021-A, from fibroblasts of a 4-year-
Externí odkaz:
https://doaj.org/article/3af5809a4a3547f581464dae471edb82
Autor:
Maximilian Deest, Jelte Wieting, Maximilian Michael Jakob, Stephanie Deest-Gaubatz, Adrian Groh, Johanna Seifert, Sermin Toto, Stefan Bleich, Helge Frieling, Christian K. Eberlein
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-8 (2022)
Abstract Background Prader–Willi syndrome (PWS) is a rare neurodevelopmental disorder based on a loss of paternally expressed genes in chromosome segment 15q11-13. Behavioral traits such as temper outbursts, stereotypic, and ritualistic behavior, a
Externí odkaz:
https://doaj.org/article/400fe37ecfb946909614b20b9a1f56e5
Autor:
Hannah M. Heseding, Kirsten Jahn, Christian K. Eberlein, Jelte Wieting, Hannah B. Maier, Phileas J. Proskynitopoulos, Alexander Glahn, Stefan Bleich, Helge Frieling, Maximilian Deest
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Prader-Willi syndrome (PWS) is a rare neurodevelopmental disorder caused by a loss of usually paternally expressed, maternally imprinted genes located on chromosome 15q11-q13. Individuals with PWS display a specific behavioral phenotype and
Externí odkaz:
https://doaj.org/article/fc7e7b943f0e4d5e8631edc777c05481
Autor:
Johanna Seifert, Christian Ihlefeld, Tristan Zindler, Christian K. Eberlein, Maximilian Deest, Stefan Bleich, Sermin Toto, Catharina Meissner
Publikováno v:
Psychiatry International, Vol 2, Iss 3, Pp 310-324 (2021)
Studies have consistently determined that patients with acute psychosis are more likely to be involuntarily admitted, although few studies examine specific risk factors of involuntary admission (IA) among this patient group. Data from all patients pr
Externí odkaz:
https://doaj.org/article/859a0193d3e3439890226e689d2a934c
Autor:
Kerim Abdelkhalek, Mathias Rhein, Maximilian Deest, Vanessa Buchholz, Stefan Bleich, Ralf Lichtinghagen, Benjamin Vyssoki, Helge Frieling, Marc Muschler, Phileas Johannes Proskynitopoulos, Alexander Glahn
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
IntroductionSeveral studies reported dysregulated protein levels of brain-derived neurotrophic factor (BDNF) in smokers and during cessation. However, the epigenetic regulation of the BDNF gene has not yet been investigated. We measured the plasma le
Externí odkaz:
https://doaj.org/article/f9789a4e711c4f1c803fee4431ece24b
Autor:
Martin Lennart Schulze Westhoff, Johannes Ladwig, Johannes Heck, Rasmus Schülke, Adrian Groh, Maximilian Deest, Stefan Bleich, Helge Frieling, Kirsten Jahn
Publikováno v:
Brain Sciences, Vol 12, Iss 1, p 11 (2021)
Psychotic disorders often run a chronic course and are associated with a considerable emotional and social impact for patients and their relatives. Therefore, early recognition, combined with the possibility of preventive intervention, is urgently wa
Externí odkaz:
https://doaj.org/article/3fe7b6797e344b3fac2561939bf0c95d
Autor:
Philipp Solbach, Sandra Westhaus, Maximilian Deest, Eva Herrmann, Thomas Berg, Michael P. Manns, Sandra Ciesek, Christoph Sarrazin, Thomas von Hahn
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 1, Iss 3, Pp 285-294.e1 (2015)
Background & Aims: Hepatitis C virus (HCV) cell entry is mediated by several cell surface receptors, including scavenger receptor class B type I (SR-BI). Oxidized low density lipoprotein (oxLDL) inhibits the interaction between HCV and SR-BI in a non
Externí odkaz:
https://doaj.org/article/f3b30547f7254928a70b892ccba5d061