Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Maximilian Blum"'
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 1, Pp 135-148 (2019)
A chiral lipidomics approach was established for comprehensive profiling of regio- and stereoisomeric monoepoxy and monohydroxy metabolites of long-chain PUFAs as generated enzymatically by cytochromes P450 (CYPs), lipoxygenases (LOXs), and cyclooxyg
Externí odkaz:
https://doaj.org/article/c755ecf6120e473687eb110d68274daa
Publikováno v:
MicrobiologyOpen, Vol 8, Iss 7, Pp n/a-n/a (2019)
Abstract Lipoxygenases are lipid peroxidizing enzymes, which frequently occur in higher plants and mammals. These enzymes are also expressed in lower multicellular organisms but here they are not widely distributed. In bacteria, lipoxygenases rarely
Externí odkaz:
https://doaj.org/article/c5783de00788483ca3736383ba9612fe
Autor:
Ye Zhu, Maximilian Blum, Uwe Hoff, Tim Wesser, Mandy Fechner, Christina Westphal, Dennis Gürgen, Rusan Ali Catar, Aurelie Philippe, Kaiyin Wu, Gordana Bubalo, Michael Rothe, Steven M Weldon, Duska Dragun, Wolf-Hagen Schunck
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0145645 (2016)
AIM:20-hydroxyeicosatetraenoic acid (20-HETE) and epoxyeicosatrienoic acids (EETs) are cytochrome P450 (CYP)-dependent eicosanoids that play opposite roles in the regulation of vascular tone, inflammation, and apoptosis. 20-HETE aggravates, whereas E
Externí odkaz:
https://doaj.org/article/bf252068991546c0a8d08f0a533dd4f6
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 1, Pp 135-148 (2019)
A chiral lipidomics approach was established for comprehensive profiling of regio- and stereoisomeric monoepoxy and monohydroxy metabolites of long-chain PUFAs as generated enzymatically by cytochromes P450 (CYPs), lipoxygenases (LOXs), and cyclooxyg
Autor:
Stefan F. Kirsch, Martin Jübermann, Hartmut Kühn, Michael Rothe, Katharina M. Rund, Kateryna Goloshchapova, Wolf-Hagen Schunck, Nils Helge Schebb, Laura Kutzner, Maximilian Blum
Publikováno v:
Biochimica et biophysica acta. Molecular and cell biology of lipids. 1865(12)
Lipoxygenases (ALOX) are lipid peroxidizing enzymes that catalyze the biosynthesis of pro- and anti-inflammatory lipid mediators and have been implicated in (patho-)physiological processes. In humans, six functional ALOX isoforms exist and their arac
Autor:
Ulrich Laufs, D Lavall, Marios Antoniadis, Ulf Landmesser, Maximilian Blum, David M. Leistner, Karsten Lenk, Andreas Hagendorff, Samira Zeynalova, Valentin Schwarzbach
Publikováno v:
The International Journal of Cardiovascular Imaging
Contrast-flow quantitative flow ratio (cQFR) is a new technology for quantitative evaluation of coronary stenosis using computational fluid dynamics based on angiograms. The aim of this study was to assess the sensitivity and specificity of cQFR to d
Autor:
Erdmann Seeliger, Jan Hentschel, Mandy Fechner, Dennis Gürgen, Michael Haase, Ye Zhu, Duska Dragun, Wolf-Hagen Schunck, Karen Arakelyan, Bert Flemming, John R. Falck, Andreas Pohlmann, Maximilian Blum, Uwe Hoff, Michael Rothe, Gordana Bubalo, Vijaya L. Manthati, Thoralf Niendorf
Publikováno v:
Acta Physiol (Oxf)
Aim Imbalances in cytochrome P450 (CYP)-dependent eicosanoid formation may play a central role in ischemic acute kidney injury (AKI). We reported previously that inhibition of 20-hydroxyeicosatetraenoic acid (20-HETE) action ameliorated ischemia/repe
Publikováno v:
MicrobiologyOpen
MicrobiologyOpen, Vol 8, Iss 7, Pp n/a-n/a (2019)
MicrobiologyOpen, Vol 8, Iss 7, Pp n/a-n/a (2019)
Lipoxygenases are lipid peroxidizing enzymes, which frequently occur in higher plants and mammals. These enzymes are also expressed in lower multicellular organisms but here they are not widely distributed. In bacteria, lipoxygenases rarely occur and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::567c96af68a60f337b3307c842d28cb3
https://doi.org/10.17169/refubium-2354
https://doi.org/10.17169/refubium-2354
Autor:
Tamara Margit Jutta Pahlitzsch, Marion Ludwig, Maximilian Blum, Pontus B. Persson, Stefanie Dietze, Andreas Patzak, Diana Braun, Zhi Zhao Liu, Eckehardt Kupsch, Wolf-Hagen Schunck, Amira Al-Masri
Publikováno v:
American journal of physiology. Renal physiology. 314(3)
We tested the hypothesis that hypoxia-reoxygenation (H/R) augments vasoreactivity to angiotensin II (ANG II). In particular, we compared an in situ live kidney slice model with isolated afferent arterioles (C57Bl6 mice) to assess the impact of tubule
Autor:
Wolf-Hagen Schunck, Duska Dragun, Nina Himmerkus, Tom Roschel, Maximilian Blum, Hans Krause, Sebastian Bachmann, Robert Labes, Alexander Paliege, Allein Plain, Markus Bleich, Torsten Giesecke, Kerim Mutig, Michael Rothe, Steven M. Weldon, Christin Boldt, Ahmed Magheli
Publikováno v:
American journal of physiology. Renal physiology. 311(6)
Activation of the thick ascending limb (TAL) Na+-K+-2Cl−cotransporter (NKCC2) by the antidiuretic hormone arginine vasopressin (AVP) is an essential mechanism of renal urine concentration and contributes to extracellular fluid and electrolyte homeo