Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Maximilian Bellut"'
Autor:
Maximilian Bellut, Michael Bieber, Peter Kraft, Alexander N. R. Weber, Guido Stoll, Michael K. Schuhmann
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-10 (2023)
Abstract Background Ischemic stroke immediately evokes a strong neuro-inflammatory response within the vascular compartment, which contributes to primary infarct development under vessel occlusion as well as further infarct growth despite recanalizat
Externí odkaz:
https://doaj.org/article/b07d3dec5ac44a9a93d01fbfd489fe2a
Dimethyl Fumarate Attenuates Lymphocyte Infiltration and Reduces Infarct Size in Experimental Stroke
Autor:
Michael K. Schuhmann, Friederike Langhauser, Lena Zimmermann, Maximilian Bellut, Christoph Kleinschnitz, Felix Fluri
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15540 (2023)
Ischemic stroke is associated with exacerbated tissue damage caused by the activation of immune cells and the initiation of other inflammatory processes. Dimethyl fumarate (DMF) is known to modulate the immune response, activate antioxidative pathway
Externí odkaz:
https://doaj.org/article/995433e1722b41a2963ee4c542ef8079
Publikováno v:
Cell Death and Disease, Vol 13, Iss 1, Pp 1-10 (2021)
Abstract In ischemic stroke (IS) impairment of the blood–brain barrier (BBB) has an important role in the secondary deterioration of neurological function. BBB disruption is associated with ischemia-induced inflammation, brain edema formation, and
Externí odkaz:
https://doaj.org/article/61145514835b4f32a498b051fb0d0c11
Autor:
Michael Bieber, Michael K. Schuhmann, Maximilian Bellut, David Stegner, Katrin G. Heinze, Mirko Pham, Bernhard Nieswandt, Guido Stoll
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 16, p 9496 (2022)
During ischemic stroke, infarct growth before recanalization diminishes functional outcome. Hence, adjunct treatment options to protect the ischemic penumbra before recanalization are eagerly awaited. In experimental stroke targeting two different pa
Externí odkaz:
https://doaj.org/article/c22ade9e7e7b4aefb23045957e0d66b9
Autor:
Maximilian Bellut, Anthony T. Raimondi, Axel Haarmann, Lena Zimmermann, Guido Stoll, Michael K. Schuhmann
Publikováno v:
Biomedicines, Vol 10, Iss 4, p 762 (2022)
Thrombolysis with recombinant tissue plasminogen activator (rt-PA) is a mainstay of acute ischemic stroke treatment but is associated with bleeding complications, especially after prolonged large vessel occlusion. Recently, inhibition of the NLRP3 in
Externí odkaz:
https://doaj.org/article/c0e38cc3255343f497292fe2ef624118
Autor:
Maximilian Bellut, Michael Bieber, Peter Kraft, Alexander N. R. Weber, Guido Stoll, Michael K. Schuhmann
Publikováno v:
Journal of neuroinflammation. 20(1)
Background Ischemic stroke immediately evokes a strong neuro-inflammatory response within the vascular compartment, which contributes to primary infarct development under vessel occlusion as well as further infarct growth despite recanalization, refe