Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Maximilian, Schindler"'
Zyxin is important for the stability and function of podocytes, especially during mechanical stretch
Autor:
Felix Kliewe, Florian Siegerist, Elke Hammer, Jaafar Al-Hasani, Theodor Rolf Jakob Amling, Jonas Zeno Eddy Hollemann, Maximilian Schindler, Vedran Drenic, Stefan Simm, Kerstin Amann, Christoph Daniel, Maja Lindenmeyer, Markus Hecker, Uwe Völker, Nicole Endlich
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Podocyte detachment due to mechanical stress is a common issue in hypertension-induced kidney disease. This study highlights the role of zyxin for podocyte stability and function. We have found that zyxin is significantly up-regulated in pod
Externí odkaz:
https://doaj.org/article/aeac6a2a22ce4682a2efff53ba47a07d
Autor:
Tjessa Bondue, Sante Princiero Berlingerio, Florian Siegerist, Elena Sendino-Garví, Maximilian Schindler, Hans Jacobus Baelde, Sara Cairoli, Bianca Maria Goffredo, Fanny Oliveira Arcolino, Jürgen Dieker, Manoe Jacoba Janssen, Nicole Endlich, Roland Brock, Rik Gijsbers, Lambertus van den Heuvel, Elena Levtchenko
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Messenger RNA (mRNA) therapies are emerging in different disease areas, but have not yet reached the kidney field. Our aim was to study the feasibility to treat the genetic defect in cystinosis using synthetic mRNA in cell models and ctns
Externí odkaz:
https://doaj.org/article/e4841b6ebf164c40bbddf71bdbfa5308
Autor:
Stephan Michalik, Florian Siegerist, Raghavendra Palankar, Kati Franzke, Maximilian Schindler, Alexander Reder, Ulrike Seifert, Clemens Cammann, Jan Wesche, Leif Steil, Christian Hentschker, Manuela Gesell-Salazar, Emil Reisinger, Martin Beer, Nicole Endlich, Andreas Greinacher, Uwe Völker
Publikováno v:
Haematologica, Vol 107, Iss 4 (2022)
Vector-based SARS-CoV-2 vaccines have been associated with vaccine- induced thrombosis with thrombocytopenia syndrome (VITT/TTS), but the causative factors are still unresolved. We comprehensively analyzed the ChAdOx1 nCoV-19 (AstraZeneca) and Ad26.C
Externí odkaz:
https://doaj.org/article/98a7cf58d6ae47778258e4ba016d16dd
Autor:
Maximilian Schindler, Antje Blumenthal, Marcus Johannes Moeller, Karlhans Endlich, Nicole Endlich
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0242436 (2020)
Podocytes are highly specialized epithelial cells that are essential for an intact glomerular filtration barrier in the kidney. Several glomerular diseases like focal segmental glomerulosclerosis (FSGS) are initially due to podocyte injury and loss.
Externí odkaz:
https://doaj.org/article/b9648c32655a482e939e7cebc754d66e
Autor:
Tjessa Bondue, Sante P. Berlingerio, Florian Siegerist, Elena Sendino-Garví, Maximilian Schindler, Sara Cairoli, Bianca M. Goffredo, Fanny O. Arcolino, Jürgen Dieker, Manoe Janssen, Nicole Endlich, Roland Brock, Rik Gijsbers, Lambertus van den Heuvel, Elena Levtchenko
Messenger RNA (mRNA) therapies are emerging in different disease areas, but have not yet reached the kidney field. Our aim was to study the feasibility to correct the genetic defect in nephropathic cystinosis using synthetic mRNA. Cystinosis is a pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b23a4bb539cee4a217b1a036634bfe03
https://doi.org/10.1101/2023.04.28.538106
https://doi.org/10.1101/2023.04.28.538106
Publikováno v:
Revue Médicale Suisse. 18:1455-1459
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0245a4ed8bdd69dc9ccc54936f4f733
https://doi.org/10.53738/revmed.2022.18.790-2.1455
https://doi.org/10.53738/revmed.2022.18.790-2.1455
Publikováno v:
Revue medicale suisse. 18(790-2)
Low back pain is a common symptom in athletes, hindering their activity. The etiology is tightly linked to the type of sport, often a consequence of repetitive movements, high pressures and strain being applied to the spine and adjacent muscular and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b40a5473a44d5bd2fa5a94962902990e
https://pubmed.ncbi.nlm.nih.gov/35856514
https://pubmed.ncbi.nlm.nih.gov/35856514
Publikováno v:
Revue medicale suisse. 18(790-2)
Numerous studies highlight the psychological aspect being the most frequent factors limiting the resumption of sport, following an anterior cruciate ligament reconstruction surgery, even before strength, the capacity of performing high impact pivotin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4534672e644525f467fb5c542a6b9cbd
https://pubmed.ncbi.nlm.nih.gov/35856513
https://pubmed.ncbi.nlm.nih.gov/35856513
Autor:
Maximilian Schindler, Florian Siegerist, Tim Lange, Sophia-Marie Bach, Marianne Klawitter, Jochen Gehrig, Bernhard Ellinger, Sheraz Gul, Nicole Endlich
Publikováno v:
Nephrology Dialysis Transplantation. 37
BACKGROUND AND AIMS Focal segmental sclerosis (FSGS) is a severe histopathological condition which often results in end-stage renal disease. Loss of podocytes and severe changes of podocyte foot process morphology accompanied by proteinuria are the h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c30b7edd5f6fcd54a2e8cdde860709d
https://doi.org/10.1093/ndt/gfac113.004
https://doi.org/10.1093/ndt/gfac113.004
Publikováno v:
Revue Médicale Suisse. 16:1421-1427
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f596806c0b62ff327e11235d649617a1
https://doi.org/10.53738/revmed.2020.16.701.1421
https://doi.org/10.53738/revmed.2020.16.701.1421