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pro vyhledávání: '"Maximilian, Julve"'
Introduction: Despite the recent advances in the treatment of malignant melanoma with immunotherapy and BRAF/MEK targeted agents, advanced disease still beholds a poor prognosis for a significant proportion of patients. Cyclin-dependent kinase (CDK)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f43c47538c9f149d468e915c8b4854
http://hdl.handle.net/10044/1/83813
http://hdl.handle.net/10044/1/83813
Publikováno v:
BMJ Case Rep
A 69-year-old man with a background of hypertension, benign prostatic hypertrophy and Eastern Cooperative Oncology Group (ECOG) performance status 0, presented with abdominal pain and weight loss in May 2018. Biochemistry and full blood count were un
Autor:
Ellis Dell, Alexandra Hadjimichalis, Mark Openshaw, Maximilian Julve, T. Newsom-Davis, Stephanie Slater, Ruth Caulkin
Publikováno v:
Lung Cancer. 156:S20
Autor:
Sanjay Popat, Maximilian Julve, James Clark, T. Newsom-Davis, Ellis Dell, Adam Januszewski, Ravindhi Murphy
Publikováno v:
Web of Science
Autor:
Gerard Walls, James Larkin, E. Kalaitzaki, Lavinia Spain, Maximilian Julve, K. O’Meara, Jeremy Rees, M. E. Gore, Samra Turajlic, Thomas A. Schmid
Publikováno v:
Annals of Oncology. 28:377-385
Background: Treatment with immune checkpoint inhibitors (ICPi) has greatly improved survival for patients with advanced melanoma in recent years. Anti-CTLA-4 and anti-PD1 antibodies have been approved following large Phase III trials. Immunerelated n
Autor:
Petros Grivas, Jonathan Krell, Maximilian Julve, Mark P. Lythgoe, Philip Savage, Ali Raza Khaki
Publikováno v:
Journal of Clinical Oncology. 39:22-22
22 Background: GU cancers account for 1 in 5 of new cancer diagnoses in the USA. Significant racial disparities exist in terms of incidence, treatment and outcomes. Current FDA clinical trial guidance advises race reporting as a minimum of 5 categori
Combination dabrafenib and trametinib in the management of advanced melanoma with BRAFV600 mutations
Publikováno v:
Expert opinion on pharmacotherapy. 17(7)
In the 40-50% of advanced melanoma patients with tumors harboring BRAF V600E and V600 K mutations, BRAF inhibitors such as dabrafenib are a highly effective treatment. However, most patients develop resistance after several months on treatment. The a
Publikováno v:
BMJ case reports. 2014
A 77-year-old man with known adenocarcinoma of the gastro-oesophageal junction presented with symptoms of general deterioration associated with right-sided retro-orbital pain and visual disturbance. The visual acuity in the right eye was normal but t
Autor:
Neha, Chopra, Fatima, El-Khouly, Maximilian, Julve, Robert, Goldstein, Astrid, Mayer, Christina, Thirlwell, Tim, Meyer, Roopinder, Gillmore
Publikováno v:
In Annals of Oncology June 2014 25 Supplement 2:ii45-ii45