Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Maximilian, Bockhorn"'
Autor:
Baris Mercanoglu, Sissy-Alina Waschkowski, Elena Neuburg, Nina Schraps, Anastasios D. Giannou, Benjamin Dreyer, Sönke Harder, Markus Heine, Christian F. Krebs, Cenap Güngör, Hartmut Schlüter, Nathaniel Melling, Thilo Hackert, Maximilian Bockhorn, Christoph Wagener, Gerrit Wolters-Eisfeld
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract GALNT2, also known as polypeptide N-acetylgalactosaminyltransferase 2, is an enzyme that catalyzes the initial step of O-linked glycosylation, a crucial posttranslational modification that affects protein folding, stability, and function. Al
Externí odkaz:
https://doaj.org/article/5ba4298f991340338c50fc2c54142984
Autor:
N. Helge Meyer, Nika Kotnik, Gaetan Aime Noubissi Nzeteu, Léon C. van Kempen, Mirjam Mastik, Maximilian Bockhorn, Achim Troja
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionColorectal cancer (CRC) ranks as the third most prevalent malignancy globally, with a concerning rise in incidence among young adults. Despite progress in understanding genetic predispositions and lifestyle risk factors, the intricate mol
Externí odkaz:
https://doaj.org/article/b123182399bb45d3be3cd4183e7868e4
Publikováno v:
Surgery Open Science, Vol 11, Iss , Pp 69-72 (2023)
Introduction: Anastomotic leakage after esophagectomy with gastric-pullup is the most feared postoperative complication associated with high morbidity and mortality rates. Management of anastomotic leakage underwent an evolution in the last decade fr
Externí odkaz:
https://doaj.org/article/a2f3c8c699a042aaba22452c621ba4fa
Publikováno v:
Surgery Open Science, Vol 10, Iss , Pp 12-18 (2022)
Background: Postoperative anastomotic leakage remains a major complication of esophagectomy. The development of a reliable method of early detection of anastomotic leakage can revolutionize the management of esophageal carcinoma. Materials and Method
Externí odkaz:
https://doaj.org/article/fab7e2683cf54247be12ae72065da28a
Publikováno v:
Clinics and Practice, Vol 12, Iss 5, Pp 782-787 (2022)
Aim: Surgical resection remains the treatment of choice for curable esophageal cancer patients. Anastomotic leakage after esophagectomy with an intrathoracic anastomosis is the most feared complication, and is the main cause of postoperative morbidit
Externí odkaz:
https://doaj.org/article/ac7537aaf0e64b609ee50bcfd492b132
Publikováno v:
Clinical Endoscopy, Vol 55, Iss 1, Pp 58-66 (2022)
Background/Aims Anastomotic leakage after esophageal surgery remains a feared complication. During the last decade, management of this complication changed from surgical revision to a more conservative and endoscopic approach. However, the treatment
Externí odkaz:
https://doaj.org/article/46dd5051886a489f8ec1aecb88d5082a
Autor:
Gaetan Aime Noubissi Nzeteu, Bernhard F. Gibbs, Nika Kotnik, Achim Troja, Maximilian Bockhorn, N. Helge Meyer
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Pancreatic cancer (PC) has a complex and unique tumor microenvironment (TME). Due to the physical barrier formed by the desmoplastic stroma, the delivery of drugs to the tumor tissue is limited. The TME also contributes to resistance to various immun
Externí odkaz:
https://doaj.org/article/475189f468f740958d6e4c8a987b8398
Autor:
Julia K. Grass, Natalie Küsters, Marius Kemper, Jan Tintrup, Felix Piecha, Jakob R. Izbicki, Daniel Perez, Nathaniel Melling, Maximilian Bockhorn, Matthias Reeh
Publikováno v:
PLoS ONE, Vol 17, Iss 3 (2022)
Background Concomitant liver cirrhosis is a crucial risk factor for major surgeries. However, only few data are available concerning cirrhotic patients requiring esophagectomy for malignant disease. Methods From a prospectively maintained database of
Externí odkaz:
https://doaj.org/article/2e5faffdab024448a1cb76d657914a12
Publikováno v:
Medicina, Vol 59, Iss 3, p 434 (2023)
Background and Objectives: Though widely used, only limited data is available that shows the superiority of hybrid minimally-invasive esophagectomy (HMIE) compared to open esophagectomy (OE). The present study aimed to analyze postoperative morbidity
Externí odkaz:
https://doaj.org/article/ccc43718478646ae998ae1240f7a5b57
Autor:
Gerrit Wolters-Eisfeld, Baris Mercanoglu, Bianca T. Hofmann, Thomas Wolpers, Claudia Schnabel, Sönke Harder, Pascal Steffen, Kai Bachmann, Babett Steglich, Jörg Schrader, Nicola Gagliani, Hartmut Schlüter, Cenap Güngör, Jakob R. Izbicki, Christoph Wagener, Maximilian Bockhorn
Publikováno v:
Experimental and Molecular Medicine, Vol 50, Iss 10, Pp 1-13 (2018)
Pancreatic disorders: when protein modification misfires Reduced levels of a protein called Cosmc in the pancreas may lead to pancreatic disorders and a rare form of diabetes. Disruption to glycosylation, the process by which carbohydrates are added
Externí odkaz:
https://doaj.org/article/e4cd471544554380848bc885224144b7