Zobrazeno 1 - 10
of 233
pro vyhledávání: '"Maximilian, Ackermann"'
Autor:
Theresa E. Schäfer, Lisanne I. Knol, Ferdinand V. Haas, Anna Hartley, Sophie C.S. Pernickel, Attila Jády, Maximiliane S.C. Finkbeiner, Johannes Achberger, Stella Arelaki, Živa Modic, Katrin Schröer, Wenli Zhang, Barbara Schmidt, Philipp Schuster, Sebastian Haferkamp, Johannes Doerner, Florian Gebauer, Maximilian Ackermann, Hans-Michael Kvasnicka, Amit Kulkarni, Selas T.F. Bots, Vera Kemp, Lukas J.A.C. Hawinkels, Anna R. Poetsch, Rob C. Hoeben, Anja Ehrhardt, Antonio Marchini, Guy Ungerechts, Claudia R. Ball, Christine E. Engeland
Publikováno v:
EBioMedicine, Vol 105, Iss , Pp 105219- (2024)
Summary: Background: Pancreatic ductal adenocarcinoma (PDAC) is a tumour entity with unmet medical need. To assess the therapeutic potential of oncolytic virotherapy (OVT) against PDAC, different oncolytic viruses (OVs) are currently investigated in
Externí odkaz:
https://doaj.org/article/06247aac10bb4534989e76e11402c612
Autor:
Alessia Floerchinger, Jessica E. Klein, Maximiliane S. C. Finkbeiner, Theresa E. Schäfer, Gwendolin Fuchs, Johannes Doerner, Hubert Zirngibl, Maximilian Ackermann, Hans M. Kvasnicka, Kerry A. Chester, Dirk Jäger, Claudia R. Ball, Guy Ungerechts, Christine E. Engeland
Publikováno v:
Cell Death and Disease, Vol 14, Iss 2, Pp 1-15 (2023)
Abstract Treatment with oncolytic measles vaccines (MV) elicits activation of immune cells, including natural killer (NK) cells. However, we found that MV-activated NK cells show only modest direct cytotoxic activity against tumor cells. To specifica
Externí odkaz:
https://doaj.org/article/631734c3778d40469ec6d6b74ebecfb0
Publikováno v:
Cold Spring Harbor perspectives in medicine. 12(10)
COVID-19 has been associated with a range of illness severity-from minimal symptoms to life-threatening multisystem organ failure. The severe forms of COVID-19 appear to be associated with an angiocentric or vascular phase of the disease. In studying
Autor:
Anuhya Dayal, Jennifer M. Pan, Stacey P. Kwan, Maximilian Ackermann, Hassan A. Khalil, Steven J. Mentzer
Publikováno v:
Polymers, Vol 16, Iss 1, p 4 (2023)
Targeted drug delivery to visceral organs offers the possibility of not only limiting the required dose, but also minimizing drug toxicity; however, there is no reliable method for delivering drugs to the surface of visceral organs. Here, we used six
Externí odkaz:
https://doaj.org/article/913556498d7b432db8fbe70b841ceee1
Autor:
R. Patrick Xian, Claire L. Walsh, Stijn E. Verleden, Willi L. Wagner, Alexandre Bellier, Sebastian Marussi, Maximilian Ackermann, Danny D. Jonigk, Joseph Jacob, Peter D. Lee, Paul Tafforeau
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-10 (2022)
Measurement(s) Human left lung Technology Type(s) X-Ray Phase-Contrast Imaging
Externí odkaz:
https://doaj.org/article/2471418d6dc94d60b99ee7984241f0e5
Autor:
Alex V. Postma, Christina K. Rapp, Katrin Knoflach, Alexander E. Volk, Johannes R. Lemke, Maximilian Ackermann, Nicolas Regamey, Philipp Latzin, Lucas Celant, Samara M.A. Jansen, Harm J. Bogaard, Aho Ilgun, Mariëlle Alders, Karin Y. van Spaendonck-Zwarts, Danny Jonigk, Christoph Klein, Stefan Gräf, Christian Kubisch, Arjan C. Houweling, Matthias Griese
Publikováno v:
Genetics in Medicine Open, Vol 1, Iss 1, Pp 100811- (2023)
Purpose: The aim of this study was to identify the monogenic cause of pulmonary arterial hypertension (PAH), a multifactorial and often fatal disease, in 2 unrelated consanguine families. Methods: We performed exome sequencing and validated variant p
Externí odkaz:
https://doaj.org/article/dc7a871eb18547b29046bbf552c654c5
Autor:
Maximilian Ackermann, Jan C. Kamp, Christopher Werlein, Claire L. Walsh, Helge Stark, Verena Prade, Rambabu Surabattula, Willi L. Wagner, Catherine Disney, Andrew J. Bodey, Thomas Illig, Diana J. Leeming, Morten A. Karsdal, Alexandar Tzankov, Peter Boor, Mark P. Kühnel, Florian P. Länger, Stijn E. Verleden, Hans M. Kvasnicka, Hans H. Kreipe, Axel Haverich, Stephen M. Black, Axel Walch, Paul Tafforeau, Peter D. Lee, Marius M. Hoeper, Tobias Welte, Benjamin Seeliger, Sascha David, Detlef Schuppan, Steven J. Mentzer, Danny D. Jonigk
Publikováno v:
EBioMedicine, Vol 85, Iss , Pp 104296- (2022)
Summary: Background: COVID-19 is characterized by a heterogeneous clinical presentation, ranging from mild symptoms to severe courses of disease. 9–20% of hospitalized patients with severe lung disease die from COVID-19 and a substantial number of
Externí odkaz:
https://doaj.org/article/b4f5f451eaf04dc4b18d8490c6c059a3
Publikováno v:
Journal of Investigative Surgery, Vol 34, Iss 10, Pp 1158-1164 (2021)
Introduction Allogeneic cortical bone plates (CP) are used for alveolar ridge augmentation. Since CP are freeze-dried and dehydrated during processing, the breaking strength (BS) and the flexibility (FX) are reduced, resulting in a relevant risk for
Externí odkaz:
https://doaj.org/article/1570ae9224c54911890157bdfbec4128
Autor:
Amanda J Lee, Emily Feng, Marianne V Chew, Elizabeth Balint, Sophie M Poznanski, Elizabeth Giles, Ali Zhang, Art Marzok, Spencer D Revill, Fatemeh Vahedi, Anisha Dubey, Ehab Ayaub, Rodrigo Jimenez-Saiz, Joshua J C McGrath, Tyrah M Ritchie, Manel Jordana, Danny D Jonigk, Maximilian Ackermann, Kjetil Ask, Matthew Miller, Carl D Richards, Ali A Ashkar
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1010471 (2022)
The ability to treat severe viral infections is limited by our understanding of the mechanisms behind virus-induced immunopathology. While the role of type I interferons (IFNs) in early control of viral replication is clear, less is known about how I
Externí odkaz:
https://doaj.org/article/bac7c41243064cfda47eb006b0f0cc7c
Autor:
Stijn E. Verleden, Peter Braubach, Christopher Werlein, Edith Plucinski, Mark P. Kuhnel, Annemiek Snoeckx, Haroun El Addouli, Tobias Welte, Axel Haverich, Florian P. Laenger, Sabine Dettmer, Patrick Pauwels, Veronique Verplancke, Paul E. Van Schil, Therese Lapperre, Johanna M. Kwakkel-Van-Erp, Maximilian Ackermann, Jeroen M. H. Hendriks, Danny Jonigk
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Pathology and radiology are complimentary tools, and their joint application is often crucial in obtaining an accurate diagnosis in non-neoplastic pulmonary diseases. However, both come with significant limitations of their own: Computed Tomography (
Externí odkaz:
https://doaj.org/article/9d7fd2cd5ac24be39671d93b5803590a