Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Maximiliaan Schillebeeckx"'
Autor:
Chris Fiore, Saik Kia Goh, Brett B Maricque, Maximiliaan Schillebeeckx, S. Kyle Austin, Nathan L. Vanderford
Publikováno v:
Technology Transfer and Entrepreneurship. 2:31-36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79117276fe93a30815c2b4b743fc55e4
https://doi.org/10.2174/2213809902666150216223802
https://doi.org/10.2174/2213809902666150216223802
Autor:
Gustavo Turecki, Mikhail Bilenky, Joseph F. Costello, Chris Fiore, Martin Hirst, Tracy J. Ballinger, Nina Thiessen, Allen Delaney, Cydney B. Nielsen, Ting Wang, Vivi M. Heine, David Haussler, Brett E. Johnson, Xiaoyun Xing, Steven J.M. Jones, Yongjun Zhao, Shaun D. Fouse, Marco A. Marra, Raman P. Nagarajan, David H. Rowitch, Richard Varhol, Alika K. Maunakea, Chibo Hong, Maximiliaan Schillebeeckx, Cletus D'Souza, Ksenya Shchors
Publikováno v:
Nature, vol 466, iss 7303
Nature, 466(7303), 253-7. Nature Publishing Group
Nature
Maunakea, A K, Nagarajan, R P, Bilenky, M, Ballinger, T J, D'Souza, C, Fouse, S D, Johnson, B E, Hong, C, Nielsen, C, Zhao, Y, Turecki, G, Delaney, A, Varhol, R, Thiessen, N, Shchors, K, Heine, V M, Rowitch, D H, Xing, X, Fiore, C, Schillebeeckx, M, Jones, S J M, Haussler, D, Marra, M A, Hirst, M, Wang, T & Costello, J F 2010, ' Conserved role of intragenic DNA methylation in regulating alternative promoters ', Nature, vol. 466, no. 7303, pp. 253-7 . https://doi.org/10.1038/nature09165
Nature, 466(7303), 253-7. Nature Publishing Group
Nature
Maunakea, A K, Nagarajan, R P, Bilenky, M, Ballinger, T J, D'Souza, C, Fouse, S D, Johnson, B E, Hong, C, Nielsen, C, Zhao, Y, Turecki, G, Delaney, A, Varhol, R, Thiessen, N, Shchors, K, Heine, V M, Rowitch, D H, Xing, X, Fiore, C, Schillebeeckx, M, Jones, S J M, Haussler, D, Marra, M A, Hirst, M, Wang, T & Costello, J F 2010, ' Conserved role of intragenic DNA methylation in regulating alternative promoters ', Nature, vol. 466, no. 7303, pp. 253-7 . https://doi.org/10.1038/nature09165
Although it is known that the methylation of DNA in 5' promoters suppresses gene expression, the role of DNA methylation in gene bodies is unclear. In mammals, tissue- and cell type-specific methylation is present in a small percentage of 5' CpG isla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f24e873e54aeb52d94220405df9a455
https://doi.org/10.1038/nature09165
https://doi.org/10.1038/nature09165
Autor:
Ann-Kathrin Löbs, Robi D. Mitra, Maximiliaan Schillebeeckx, Theresa Röhrig, Rebecca Cochran, Theresa Hiller, Marjut Pihlajoki, Anja Schrade, Patrick Y. Jay, Franziska Thol, Wei Yang, David B. Wilson, Elisabeth Gretzinger, Markku Heikinheimo
Gonadectomy (GDX) induces sex steroid-producing adrenocortical tumors in certain mouse strains and in the domestic ferret. Transcriptome analysis and DNA methylation mapping were used to identify novel genetic and epigenetic markers of GDX-induced ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9022f0266b5d9ce0e5f176b5568a0e1
https://europepmc.org/articles/PMC4262703/
https://europepmc.org/articles/PMC4262703/
Autor:
Anja Schrade, Ricarda Ziegler, Theresa Röhrig, Rebecca Cochran, Markku Heikinheimo, Maximiliaan Schillebeeckx, David B. Wilson, Marjut Pihlajoki, Robi D. Mitra
Publikováno v:
Molecular and cellular endocrinology. 408
Cell fate decisions are integral to zonation and remodeling of the adrenal cortex. Animal models exhibiting ectopic differentiation of gonadal-like cells in the adrenal cortex can shed light on the molecular mechanisms regulating steroidogenic cell f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3570adb9219dd0cc69845ee97f29130f
https://pubmed.ncbi.nlm.nih.gov/25498963
https://pubmed.ncbi.nlm.nih.gov/25498963
Publikováno v:
Nature biotechnology. 31(10)
A new type of initiative is empowering graduate students and postdocs to reshape their academic training, providing another avenue to express their passion for research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98e15c942c479b45c442a922a6b1e748
https://pubmed.ncbi.nlm.nih.gov/24104758
https://pubmed.ncbi.nlm.nih.gov/24104758
Autor:
Ann-Kathrin Löbs, Maximiliaan Schillebeeckx, Anja Schrade, Robi D. Mitra, David B. Wilson, Marjut Pihlajoki
Publikováno v:
Nucleic Acids Research
DNA methylation is a mechanism for long-term transcriptional regulation and is required for normal cellular differentiation. Failure to properly establish or maintain DNA methylation patterns leads to cell dysfunction and diseases such as cancer. Ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd3fcc023d29b2f344ca180deed1807
https://doi.org/10.1093/nar/gkt230
https://doi.org/10.1093/nar/gkt230
Autor:
Robi D. Mitra, Paul J. Goodfellow, Michael R. Brent, Brian C. Haynes, Maximiliaan Schillebeeckx, Katherine B. Chiappinelli
Publikováno v:
Cancer Research. 71:1173-1173
DICER1 is required for the generation of mature microRNAs (22-24 nt miRNAs) and other short noncoding RNAs. Several lines of evidence point to DICER1's role as a tumor suppressor. In particular, reduced DICER1 levels are associated with adverse outco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00402bd2c9be0c238aa7a04e0efea035
https://doi.org/10.1158/1538-7445.am2011-1173
https://doi.org/10.1158/1538-7445.am2011-1173