Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Maxime Vergouts"'
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Akademický článek
Inflammation-associated regulation of RGS in astrocytes and putative implication in neuropathic pain
Autor: Pierre J. Doyen, Maxime Vergouts, Amandine Pochet, Nathalie Desmet, Sabien van Neerven, Gary Brook, Emmanuel Hermans
Publikováno v: Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-11 (2017)
Abstract Background Regulators of G-protein signaling (RGS) are major physiological modulators of G-protein-coupled receptors (GPCR) signaling. Several GPCRs expressed in both neurons and astrocytes participate in the central control of pain processi
Externí odkaz: https://doaj.org/article/f7145072bd09415d90e5d91c47590bc2
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2
Amyloid Precursor Protein (APP) Controls the Expression of the Transcriptional Activator Neuronal PAS Domain Protein 4 (NPAS4) and Synaptic GABA Release
Autor: Céline Vrancx, Pierre J. Doyen, Bernadette Tasiaux, Serena Stanga, Maxime Vergouts, Pascal Kienlen-Campard, Roberta Gualdani, Nathalie Pierrot, Philippe Gailly, Jean-Noël Octave, Anna Doshina, Rémi Opsomer, Florian Perrin, Sabrina Contino
Publikováno v: eNeuro, Vol. 7, no. 3, p. ENEURO.0322-19.202 [1-18] (2020)
eNeuro
Visual Abstract
The amyloid precursor protein (APP) has been extensively studied as the precursor of the β-amyloid (Aβ) peptide, the major component of the senile plaques found in the brain of Alzheimer’s disease (AD) patients. However, the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::177f160d38cf853ee72492a0b42d18a3
https://hdl.handle.net/2078.1/230453
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3
Constitutive downregulation protein kinase C epsilon in hSOD1G93Aastrocytes influences mGluR5 signaling and the regulation of glutamate uptake
Autor: Emmanuel Hermans, Pierre J. Doyen, Maxime Vergouts, Rémi Opsomer, Michael Peeters
Publikováno v: Glia. 66:749-761
Accumulating evidence indicates that motor neuron degeneration in amyotrophic lateral sclerosis (ALS) is a non-cell-autonomous process and that impaired glutamate clearance by astrocytes, leading to excitotoxicity, could participate in progression of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cc9ecb6d48d48e9d6408c409a9fa0c80
https://doi.org/10.1002/glia.23279
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4
Early ALS-type gait abnormalities in AMP-dependent protein kinase-deficient mice suggest a role for this metabolic sensor in early stages of the disease
Autor: Olivier Schakman, André-Guilhem Calas, Géraldine Genard, Emmanuel Hermans, Anthony Sternotte, Caroline Ingelbrecht, Maxime Vergouts, Claudia Marinangeli
Publikováno v: Metabolic Brain Disease. 30:1369-1377
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the selective loss of motoneurons. While the principal cause of the disease remains so far unknown, the onset and progression of the pathology are increasingly associ
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc81e7664c6e5a4b82b24b02a6fdbed0
https://doi.org/10.1007/s11011-015-9706-9
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5
The anti-inflammatory peptide stearyl-norleucine-VIP delays disease onset and extends survival in a rat model of inherited amyotrophic lateral sclerosis
Autor: Amélie Dumont, Nathalie Desmet, Ronald Deumens, Alessandro Gallo, Maxime Vergouts, Stéphanie Goursaud, Emmanuel Hermans, Sabrina Schäfer
Publikováno v: Experimental Neurology. 263:91-101
Vasoactive intestinal peptide (VIP) has potent immune modulatory actions that may influence the course of neurodegenerative disorders associated with chronic inflammation. Here, we show the therapeutic benefits of a modified peptide agonist stearyl-n
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::086b43e101753201e81af1183121e6b9
https://doi.org/10.1016/j.expneurol.2014.09.022
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6
Constitutive downregulation protein kinase C epsilon in hSOD1
Autor: Maxime, Vergouts, Pierre J, Doyen, Michael, Peeters, Remi, Opsomer, Emmanuel, Hermans
Publikováno v: Glia. 66(4)
Accumulating evidence indicates that motor neuron degeneration in amyotrophic lateral sclerosis (ALS) is a non-cell-autonomous process and that impaired glutamate clearance by astrocytes, leading to excitotoxicity, could participate in progression of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6689725fbd2c79e4c3ef69877b545e2c
https://pubmed.ncbi.nlm.nih.gov/29266405
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7
Inflammation-associated regulation of RGS in astrocytes and putative implication in neuropathic pain
Autor: Gary A. Brook, Nathalie Desmet, Emmanuel Hermans, Sabien Geraldine Antonia van Neerven, Pierre J. Doyen, Maxime Vergouts, Amandine Pochet
Publikováno v: Journal of Neuroinflammation, Vol. 14, no. 1, p. 209 ([1-11])
Journal of Neuroinflammation
Journal of neuroinflammation 14(1), 209 (2017). doi:10.1186/s12974-017-0971-x
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-11 (2017)
Journal of neuroinflammation : JNI 14(1), 209 (2017). doi:10.1186/s12974-017-0971-x
Published by BioMed Central, London
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e80e07961a519a95959280d94f8eff5
https://hdl.handle.net/2078.1/200194
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8
PKC epsilon-dependent calcium oscillations associated with metabotropic glutamate receptor 5 prevent agonist-mediated receptor desensitization in astrocytes
Autor: Rémi Opsomer, Michael Peeters, Pierre J. Doyen, Maxime Vergouts, Thomas Michiels, Emmanuel Hermans
Publikováno v: Journal of neurochemistry. 141(3)
A critical role has been assigned to protein kinase C (PKC)e in the control of intracellular calcium oscillations triggered upon activation of type 5 metabotropic glutamate receptor (mGluR5) in cultured astrocytes. Nevertheless, the physiological sig
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f158af687189edd0a240235c59cc64bf
https://pubmed.ncbi.nlm.nih.gov/28266711
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9
Immunomodulatory influence of bone marrow-derived mesenchymal stem cells on neuroinflammation in astrocyte cultures
Autor: Emmanuel Hermans, Maxime Vergouts, André-Guilhem Calas, Sabrina Schäfer
Publikováno v: Journal of Neuroimmunology. 249:40-48
The therapeutic benefits associated with mesenchymal stem cells (MSCs) largely result from their immunomodulatory and neurotrophic properties. In this study, we evaluated the effects of MSCs on astrocyte cultures exposed to lipopolysaccharide. In res
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06bd98c62d2057e1f40af4e2c2b0b061
https://doi.org/10.1016/j.jneuroim.2012.04.018
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10
Opposite regulation of metabotropic glutamate receptor 3 and metabotropic glutamate receptor 5 by inflammatory stimuli in cultured microglia and astrocytes
Autor: Stéphanie Goursaud, Marylène C. Focant, Julie V Berger, Maxime Vergouts, Anthony Sternotte, Amélie Dumont, Emmanuel Hermans, André-Guilhem Calas
Publikováno v: Neuroscience. 205:29-38
Metabotropic glutamate receptors (mGluRs) were previously shown to modulate several essential functions in glial cells, including cell proliferation, glutamate uptake, neurotrophic support, and inflammatory responses. As these receptors are regularly
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd47f111fdafaa8604af4be77dbe437
https://doi.org/10.1016/j.neuroscience.2011.12.044
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