Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Maxime Teixeira"'
Autor:
Olivier Lurette, Rebeca Martín-Jiménez, Mehtab Khan, Razan Sheta, Stéphanie Jean, Mia Schofield, Maxime Teixeira, Raquel Rodriguez-Aller, Isabelle Perron, Abid Oueslati, Etienne Hebert-Chatelain
Publikováno v:
Cell Death and Disease, Vol 14, Iss 11, Pp 1-14 (2023)
Abstract Accumulation of α-synuclein aggregates in the substantia nigra pars compacta is central in the pathophysiology of Parkinson’s disease, leading to the degeneration of dopaminergic neurons and the manifestation of motor symptoms. Although s
Externí odkaz:
https://doaj.org/article/c078e0cade00424082d97a16652c017e
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102738- (2023)
Summary: Studying Parkinson’s disease (PD) is complex due to a lack of cellular models mimicking key aspects of protein pathology. Here, we present a protocol for inducing and monitoring α-synuclein aggregation in living cells using optogenetics.
Externí odkaz:
https://doaj.org/article/b08042b0e55c434dbef3971e2766a5d9
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102486- (2023)
Summary: Generation of functional human dopaminergic (DA) neurons from human induced pluripotent stem cells (hiPSCs) is a crucial tool for modeling dopamine-related human diseases and cell replacement therapies. Here, we present a protocol to combine
Externí odkaz:
https://doaj.org/article/1f3285d140484f579b21e06dacfc5a3f
Autor:
Razan Sheta, Maxime Teixeira, Walid Idi, Marion Pierre, Aurelie de Rus Jacquet, Vincent Emond, Cornelia E. Zorca, Benoît Vanderperre, Thomas M. Durcan, Edward A. Fon, Frédéric Calon, Mohamed Chahine, Abid Oueslati
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract The use of human derived induced pluripotent stem cells (hiPSCs) differentiated to dopaminergic (DA) neurons offers a valuable experimental model to decorticate the cellular and molecular mechanisms of Parkinson’s disease (PD) pathogenesis
Externí odkaz:
https://doaj.org/article/c73c57568ac04220baa369ab6de77226
Autor:
Robin Mesnage, Maxime Teixeira, Daniele Mandrioli, Laura Falcioni, Mariam Ibragim, Quinten Raymond Ducarmon, Romy Daniëlle Zwittink, Caroline Amiel, Jean-Michel Panoff, Emma Bourne, Emanuel Savage, Charles A. Mein, Fiorella Belpoggi, Michael N. Antoniou
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Using a multi-omics platform, Mesnage et al present an extensive dataset that reports the effects of low-dose pesticides frequently detected in food on Sprague-Dawley rats. This study suggests potential metabolic biomarkers that may predict health ri
Externí odkaz:
https://doaj.org/article/758142f043b4425c86e0fbbae4040907
Autor:
Morgan Bérard, Razan Sheta, Sarah Malvaut, Raquel Rodriguez-Aller, Maxime Teixeira, Walid Idi, Roxanne Turmel, Melanie Alpaugh, Marilyn Dubois, Manel Dahmene, Charleen Salesse, Jérôme Lamontagne-Proulx, Marie-Kim St-Pierre, Omid Tavassoly, Wen Luo, Esther Del Cid-Pellitero, Raza Qazi, Jae-Woong Jeong, Thomas M Durcan, Luc Vallières, Marie-Eve Tremblay, Denis Soulet, Martin Lévesque, Francesca Cicchetti, Edward A Fon, Armen Saghatelyan, Abid Oueslati
Publikováno v:
PLoS Biology, Vol 20, Iss 3, p e3001578 (2022)
Neurodegenerative disorders refer to a group of diseases commonly associated with abnormal protein accumulation and aggregation in the central nervous system. However, the exact role of protein aggregation in the pathophysiology of these disorders re
Externí odkaz:
https://doaj.org/article/2345db5e865f4420afb480af79493bdb
Publikováno v:
Biomolecules, Vol 11, Iss 9, p 1333 (2021)
Abnormal accumulation of the protein α- synuclein (α-syn) into proteinaceous inclusions called Lewy bodies (LB) is the neuropathological hallmark of Parkinson’s disease (PD) and related disorders. Interestingly, a growing body of evidence suggest
Externí odkaz:
https://doaj.org/article/c57899b30db942618b9258fe8c1499ea
Autor:
Morgan Bérard, Razan Sheta, Sarah Malvaut, Raquel Rodriguez-Aller, Maxime Teixeira, Walid Idi, Roxanne Turmel, Melanie Alpaugh, Marilyn Dubois, Manel Dahmene, Charleen Salesse, Jérôme Lamontagne-Proulx, Marie-Kim St-Pierre, Omid Tavassoly, Wen Luo, Esther Del Cid-Pellitero, Raza Qazi, Jae-Woong Jeong, Thomas M. Durcan, Luc Vallières, Marie-Eve Tremblay, Denis Soulet, Martin Lévesque, Francesca Cicchetti, Edward A. Fon, Armen Saghatelyan, Abid Oueslati
Publikováno v:
PLoS biology. 20(3)
Neurodegenerative disorders refer to a group of diseases commonly associated with abnormal protein accumulation and aggregation in the central nervous system. However, the exact role of protein aggregation in the pathophysiology of these disorders re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e7e381159550e7e526d500fb77ad3d2
https://pubmed.ncbi.nlm.nih.gov/35263320
https://pubmed.ncbi.nlm.nih.gov/35263320
Publikováno v:
Biomolecules
Biomolecules, Vol 11, Iss 1333, p 1333 (2021)
Biomolecules, Vol 11, Iss 1333, p 1333 (2021)
Abnormal accumulation of the protein α- synuclein (α-syn) into proteinaceous inclusions called Lewy bodies (LB) is the neuropathological hallmark of Parkinson’s disease (PD) and related disorders. Interestingly, a growing body of evidence suggest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64a1ad3b3ce7da1866d5800f559912eb
https://pubmed.ncbi.nlm.nih.gov/34572546
https://pubmed.ncbi.nlm.nih.gov/34572546
Autor:
Mariam Ibragim, Romy D. Zwittink, Quinten R Ducarmon, Michael Antoniou, Laura Falcioni, Maxime Teixeira, Caroline Amiel, Jean-Michel Panoff, Robin Mesnage, Daniele Mandrioli, Emma Bourne, Fiorella Belpoggi, Charles A. Mein, Emanuel Savage
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Communications Biology, 4(1). NATURE RESEARCH
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Communications Biology, 4(1). NATURE RESEARCH
Health effects of pesticides are not always accurately detected using the current battery of regulatory toxicity tests. We compared standard histopathology and serum biochemistry measures and multi-omics analyses in a subchronic toxicity test of a mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db71ebcf9525e938a54639b1d3ed734
http://europepmc.org/articles/PMC8046807
http://europepmc.org/articles/PMC8046807