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Autor:
Maxime Peltier, Cathy Gomila, Stéphanie Trudel, Patrice Morlière, Michaël Aubignat, Eric Trécherel, Jérôme Ausseil, Brigitte Gubler, Jean-Michel Heard
Publikováno v:
Journal of Neuroscience Research. 93:424-432
Mucopolysaccharidosis (MPS) type IIIB is a genetic deficiency of α-N-acetylglucosaminidase, inducing accumulation of partially degraded heparan sulfate (HS) oligosaccharides in tissues. In the central nervous system, this accumulation is associated