Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Maxime P, Look"'
Autor:
Tommaso De Marchi, Mieke A. Timmermans, Anieta M. Sieuwerts, Marcel Smid, Maxime P. Look, Nicolai Grebenchtchikov, Fred C. G. J. Sweep, Jan G. Smits, Viktor Magdolen, Carolien H. M. van Deurzen, John A. Foekens, Arzu Umar, John W. Martens
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract In a previous study, we detected a significant association between phosphoserine aminotransferase 1 (PSAT1) hyper-methylation and mRNA levels to outcome to tamoxifen treatment in recurrent disease. We here aimed to study the association of P
Externí odkaz:
https://doaj.org/article/dbc96afce5a543d8b843426a5e4e8e64
Autor:
Els M.J.J. Berns, John A. Foekens, Stefan Sleijfer, Jan G.M. Klijn, Anieta M. Sieuwerts, Marion E. Meijer-van Gelder, Maxime P. Look, Iris L. van Staveren, Kirsten Ruigrok-Ritstier, Maurice P.H.M. Jansen, Jozien Helleman
Supplementary Tables S1-S3 from Association of an Extracellular Matrix Gene Cluster with Breast Cancer Prognosis and Endocrine Therapy Response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32957e3a84a8528b37396cd7876730d9
https://doi.org/10.1158/1078-0432.22439650.v1
https://doi.org/10.1158/1078-0432.22439650.v1
Autor:
John A. Foekens, Sabine Maier, Manfred Schmitt, Jan G.M. Klijn, Marion Kiechle, Heinz Höfler, Alexander Olek, Christian Piepenbrock, Marion E. Meijer-Van Gelder, Henk Portengen, Anieta M. Sieuwerts, Joan Bolt-de Vries, Antje Kluth, Fabian Model, Nadia Harbeck, Maxime P. Look, Thomas Koenig, Inko Nimmrich, John W.M. Martens
Supplementary Table S1 from Association of DNA Methylation of Phosphoserine Aminotransferase with Response to Endocrine Therapy in Patients with Recurrent Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aaff26e2cb3f79b95d6aca016611b1f
https://doi.org/10.1158/0008-5472.22363230
https://doi.org/10.1158/0008-5472.22363230
Autor:
John A. Foekens, Sabine Maier, Manfred Schmitt, Jan G.M. Klijn, Marion Kiechle, Heinz Höfler, Alexander Olek, Christian Piepenbrock, Marion E. Meijer-Van Gelder, Henk Portengen, Anieta M. Sieuwerts, Joan Bolt-de Vries, Antje Kluth, Fabian Model, Nadia Harbeck, Maxime P. Look, Thomas Koenig, Inko Nimmrich, John W.M. Martens
To understand the biological basis of resistance to endocrine therapy is of utmost importance in patients with steroid hormone receptor–positive breast cancer. Not only will this allow us prediction of therapy success, it may also lead to novel the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f243044ba04d42db682bb035abd8451
https://doi.org/10.1158/0008-5472.c.6493611.v1
https://doi.org/10.1158/0008-5472.c.6493611.v1
Autor:
Diana E. Ramirez-Ardila, Kirsten Ruigrok-Ritstier, Jean C. Helmijr, Maxime P. Look, Steven van Laere, Luc Dirix, Els M.J.J. Berns, Maurice P.H.M. Jansen
Publikováno v:
Molecular Oncology, Vol 10, Iss 8, Pp 1363-1373 (2016)
Background PIK3CA is the most frequent somatic mutated oncogene in estrogen receptor (ER) positive breast cancer. We previously observed an association between PIK3CA genotype and aromatase inhibitors (AI) treatment outcome. This study now evaluates
Externí odkaz:
https://doaj.org/article/8ebe2c3f82f54bf49412c8044bd74e36
Autor:
Joie Ensor, Kym I E Snell, Mamas A. Mamas, Richard D Riley, Paul C. Lambert, Thomas P. A. Debray, Karel G.M. Moons, Maxime P. Look
Publikováno v:
Statistics in Medicine, 40(13), 3066-3084. John Wiley & Sons Ltd.
Individual participant data (IPD) from multiple sources allows external validation of a prognostic model across multiple populations. Often this reveals poor calibration, potentially causing poor predictive performance in some populations. However, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c4b2a10c444538ad366cf638d4b61e2
http://www.scopus.com/inward/record.url?scp=85103181943&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85103181943&partnerID=8YFLogxK
Autor:
Simone U Dalm, Willemijne A M E Schrijver, Anieta M Sieuwerts, Maxime P Look, Angelique C J Ziel-van der Made, Vanja de Weerd, John W Martens, Paul J van Diest, Marion de Jong, Carolien H M van Deurzen
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170536 (2017)
The gastrin releasing peptide receptor (GRPR) and the somatostatin receptor 2 (SSTR2) are overexpressed on primary breast cancer (BC), making them ideal candidates for receptor-mediated nuclear imaging and therapy. The aim of this study was to determ
Externí odkaz:
https://doaj.org/article/51a1fb980777414da1dd4196c537c453
The 29.5 kb APOBEC3B Deletion Polymorphism Is Not Associated with Clinical Outcome of Breast Cancer.
Autor:
Jingjing Liu, Anieta M Sieuwerts, Maxime P Look, Michelle van der Vlugt-Daane, Marion E Meijer-van Gelder, John A Foekens, Antoinette Hollestelle, John W M Martens
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161731 (2016)
Increased APOBEC3B mRNA levels are associated with a hypermutator phenotype and poor prognosis in ER-positive breast cancer patients. In addition, a 29.5 kb deletion polymorphism of APOBEC3B, resulting in an APOBEC3A-B hybrid transcript, has been ass
Externí odkaz:
https://doaj.org/article/8434c4056c56452b90631d5cdfe90e25
Autor:
Simon N Stacey, Patrick Sulem, Carlo Zanon, Sigurjon A Gudjonsson, Gudmar Thorleifsson, Agnar Helgason, Aslaug Jonasdottir, Soren Besenbacher, Jelena P Kostic, James D Fackenthal, Dezheng Huo, Clement Adebamowo, Temidayo Ogundiran, Janet E Olson, Zachary S Fredericksen, Xianshu Wang, Maxime P Look, Anieta M Sieuwerts, John W M Martens, Isabel Pajares, Maria D Garcia-Prats, Jose M Ramon-Cajal, Ana de Juan, Angeles Panadero, Eugenia Ortega, Katja K H Aben, Sita H Vermeulen, Fatemeh Asadzadeh, K C Anton van Engelenburg, Sara Margolin, Chen-Yang Shen, Pei-Ei Wu, Asta Försti, Per Lenner, Roger Henriksson, Robert Johansson, Kerstin Enquist, Göran Hallmans, Thorvaldur Jonsson, Helgi Sigurdsson, Kristin Alexiusdottir, Julius Gudmundsson, Asgeir Sigurdsson, Michael L Frigge, Larus Gudmundsson, Kristleifur Kristjansson, Bjarni V Halldorsson, Unnur Styrkarsdottir, Jeffrey R Gulcher, Kari Hemminki, Annika Lindblom, Lambertus A Kiemeney, Jose I Mayordomo, John A Foekens, Fergus J Couch, Olufunmilayo I Olopade, Daniel F Gudbjartsson, Unnur Thorsteinsdottir, Thorunn Rafnar, Oskar T Johannsson, Kari Stefansson
Publikováno v:
PLoS Genetics, Vol 6, Iss 7, p e1001029 (2010)
We used an approach that we term ancestry-shift refinement mapping to investigate an association, originally discovered in a GWAS of a Chinese population, between rs2046210[T] and breast cancer susceptibility. The locus is on 6q25.1 in proximity to t
Externí odkaz:
https://doaj.org/article/5c1f5cacc7d24dc18072e623caa67329
Autor:
Maurice P.H.M. Jansen, Ronald de Wit, John W.M. Martens, Jaco Kraan, Martijn P. Lolkema, Jean C. A. Helmijr, Silvia R. Vitale, Lisanne F. van Dessel, Stefan Sleijfer, Nick Beije, Maxime P. Look
Publikováno v:
Molecular Oncology, 11(3), 295-304. John Wiley & Sons Ltd.
Molecular Oncology
Molecular Oncology
Circulating tumor DNA (ctDNA) has emerged as a potential new biomarker with diagnostic, predictive, and prognostic applications for various solid tumor types. Before beginning large prospective clinical trials to prove the added value of utilizing ct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498ab8288b6b8c85d3aafd4735c994b3
https://doi.org/10.1002/1878-0261.12037
https://doi.org/10.1002/1878-0261.12037