Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Maxime M. Mahe"'
Autor:
Florence Blot, Justine Marchix, Miriam Ejarque, Sara Jimenez, Aline Meunier, Céline Keime, Camille Trottier, Mikaël Croyal, Céline Lapp, Maxime M. Mahe, Adèle De Arcangelis, Gérard Gradwohl
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 6, Pp 1443-1461 (2023)
Background & Aims: Enteroendocrine cells (EECs) and their hormones are essential regulators of whole-body energy homeostasis. EECs sense luminal nutrients and microbial metabolites and subsequently secrete various hormones acting locally or at a dist
Externí odkaz:
https://doaj.org/article/7d6378a8c849424181d069f1a1425799
Autor:
Rémi Duclaux-Loras, Corinne Lebreton, Jérémy Berthelet, Fabienne Charbit-Henrion, Ophelie Nicolle, Céline Revenu de Courtils, Stephanie Waich, Taras Valovka, Anis Khiat, Marion Rabant, Caroline Racine, Ida Chiara Guerrera, Júlia Baptista, Maxime M. Mahe, Michael W. Hess, Béatrice Durel, Nathalie Lefort, Céline Banal, Mélanie Parisot, Cecile Talbotec, Florence Lacaille, Emmanuelle Ecochard-Dugelay, Arzu Meltem Demir, Georg F. Vogel, Laurence Faivre, Astor Rodrigues, Darren Fowler, Andreas R. Janecke, Thomas Müller, Lukas A. Huber, Fernando Rodrigues-Lima, Frank M. Ruemmele, Holm H. Uhlig, Filippo Del Bene, Grégoire Michaux, Nadine Cerf-Bensussan, Marianna Parlato
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 10 (2022)
Variants in the UNC45A cochaperone have been recently associated with a syndrome combining diarrhea, cholestasis, deafness, and bone fragility. Yet the mechanism underlying intestinal failure in UNC45A deficiency remains unclear. Here, biallelic vari
Externí odkaz:
https://doaj.org/article/6503ecabc11443e384dfca9f5f76d443
Autor:
Camille Pochard, Jacques Gonzales, Anne Bessard, Maxime M. Mahe, Arnaud Bourreille, Nicolas Cenac, Anne Jarry, Emmanuel Coron, Juliette Podevin, Guillaume Meurette, Michel Neunlist, Malvyne Rolli-Derkinderen
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 1037-1060 (2021)
Background & Aims: Inflammatory bowel diseases (IBDs) that encompass both ulcerative colitis and Crohn’s disease are a major public health problem with an etiology that has not been fully elucidated. There is a need to improve disease outcomes and
Externí odkaz:
https://doaj.org/article/9f45c793da5f4cbb8ccec51e61f61e0b
Autor:
Fatina Siwczak, Elise Loffet, Mathilda Kaminska, Hristina Koceva, Maxime M. Mahe, Alexander S. Mosig
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The gut is a tubular organ responsible for nutrient absorption and harbors our intestinal microbiome. This organ is composed of a multitude of specialized cell types arranged in complex barrier-forming crypts and villi covered by a mucosal layer cont
Externí odkaz:
https://doaj.org/article/c3d910f6211843078f4a1f484d8570df
Autor:
Mayra Aguirre Garcia, Killian Hillion, Jean-Michel Cappelier, Michel Neunlist, Maxime M. Mahe, Nabila Haddad
Publikováno v:
Foods, Vol 11, Iss 1, p 108 (2022)
Foodborne diseases cause high morbidity and mortality worldwide. Understanding the relationships between bacteria and epithelial cells throughout the infection process is essential to setting up preventive and therapeutic solutions. The extensive stu
Externí odkaz:
https://doaj.org/article/d32b594429e44bd8b54e68bbc9135e2d
Publikováno v:
Cells, Vol 10, Iss 6, p 1331 (2021)
The gastrointestinal tract is a continuous series of organs from the mouth to the esophagus, stomach, intestine and anus that allows digestion to occur. These organs are frequently associated with chronic stress and injury during life, subjecting the
Externí odkaz:
https://doaj.org/article/82285377a42f4d82aaaa3ac405d8f333
Autor:
Kodandaramireddy Nalapareddy, Kalpana J. Nattamai, Rupali S. Kumar, Rebekah Karns, Kathryn A. Wikenheiser-Brokamp, Leesa L. Sampson, Maxime M. Mahe, Nambirajan Sundaram, Mary-Beth Yacyshyn, Bruce Yacyshyn, Michael A. Helmrath, Yi Zheng, Hartmut Geiger
Publikováno v:
Cell Reports, Vol 18, Iss 11, Pp 2608-2621 (2017)
Although intestinal homeostasis is maintained by intestinal stem cells (ISCs), regeneration is impaired upon aging. Here, we first uncover changes in intestinal architecture, cell number, and cell composition upon aging. Second, we identify a decline
Externí odkaz:
https://doaj.org/article/c6980a428dc64392a7a39bc4956b9d03
Autor:
Yuan-Hung Lo, Eunah Chung, Zhaohui Li, Ying-Wooi Wan, Maxime M. Mahe, Min-Shan Chen, Taeko K. Noah, Kristin N. Bell, Hari Krishna Yalamanchili, Tiemo J. Klisch, Zhandong Liu, Joo-Seop Park, Noah F. Shroyer
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 3, Iss 1, Pp 51-71 (2017)
Background & Aims: The transcription factor atonal homolog 1 (ATOH1) controls the fate of intestinal progenitors downstream of the Notch signaling pathway. Intestinal progenitors that escape Notch activation express high levels of ATOH1 and commit to
Externí odkaz:
https://doaj.org/article/812e4ecb55214027a0f225c8e3434964
Autor:
Amy C. Engevik, Rui Feng, Eunyoung Choi, Shana White, Nina Bertaux-Skeirik, Jing Li, Maxime M. Mahe, Eitaro Aihara, Li Yang, Betsy DiPasquale, Sunghee Oh, Kristen A. Engevik, Andrew S. Giraud, Marshall H. Montrose, Mario Medvedovic, Michael A. Helmrath, James R. Goldenring, Yana Zavros
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 2, Iss 5, Pp 605-624 (2016)
Background & Aims: During aging, physiological changes in the stomach result in more tenuous gastric tissue that is less capable of repairing injury, leading to increased susceptibility to chronic ulceration. Spasmolytic polypeptide/trefoil factor 2
Externí odkaz:
https://doaj.org/article/32c7d54435e74b8aa0fa7d00b9ae7963
Autor:
Stacy R. Finkbeiner, David R. Hill, Christopher H. Altheim, Priya H. Dedhia, Matthew J. Taylor, Yu-Hwai Tsai, Alana M. Chin, Maxime M. Mahe, Carey L. Watson, Jennifer J. Freeman, Roy Nattiv, Matthew Thomson, Ophir D. Klein, Noah F. Shroyer, Michael A. Helmrath, Daniel H. Teitelbaum, Peter J. Dempsey, Jason R. Spence
Publikováno v:
Stem Cell Reports, Vol 4, Iss 6, Pp 1140-1155 (2015)
Human intestinal organoids (HIOs) are a tissue culture model in which small intestine-like tissue is generated from pluripotent stem cells. By carrying out unsupervised hierarchical clustering of RNA-sequencing data, we demonstrate that HIOs most clo
Externí odkaz:
https://doaj.org/article/e58d3f621aa14933b2e1b3f5d4737ffd