Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Maxime Lehmann"'
Autor:
Dalia El Arawi, Cyrille Vézy, Régis Déturche, Maxime Lehmann, Horst Kessler, Monique Dontenwill, Rodolphe Jaffiol
Publikováno v:
Biophysical Reports, Vol 1, Iss 2, Pp 100021- (2021)
Over the last decades, several techniques have been developed to study cell adhesion; however, they present significant shortcomings. Such techniques mostly focus on strong adhesion related to specific protein-protein associations, such as ligand-rec
Externí odkaz:
https://doaj.org/article/5fe1e09a74694daf9b9ae4dbf3640987
Autor:
Elisabete Cruz Da Silva, Sophie Foppolo, Benoît Lhermitte, Marina Ingremeau, Hélène Justiniano, Lorraine Klein, Marie-Pierre Chenard, Romain Vauchelles, Basma Abdallah, Maxime Lehmann, Nelly Etienne-Selloum, Monique Dontenwill, Laurence Choulier
Publikováno v:
Pharmaceutics, Vol 14, Iss 10, p 1980 (2022)
Nucleic-acid aptamers are of strong interest for diagnosis and therapy. Compared with antibodies, they are smaller, stable upon variations in temperature, easy to modify, and have higher tissue-penetration abilities. However, they have been little de
Externí odkaz:
https://doaj.org/article/221e69426a9741be958a7e9614743715
Autor:
Pierre Fechter, Elisabete Cruz Da Silva, Marie-Cécile Mercier, Fanny Noulet, Nelly Etienne-Seloum, Dominique Guenot, Maxime Lehmann, Romain Vauchelles, Sophie Martin, Isabelle Lelong-Rebel, Anne-Marie Ray, Cendrine Seguin, Monique Dontenwill, Laurence Choulier
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 17, Iss , Pp 63-77 (2019)
Nucleic acid aptamers are often referred to as chemical antibodies. Because they possess several advantages, like their smaller size, temperature stability, ease of chemical modification, lack of immunogenicity and toxicity, and lower cost of product
Externí odkaz:
https://doaj.org/article/30a11660aa854869a73cb126015aaf9d
Autor:
Elisabete Cruz Da Silva, Laurence Choulier, Jessica Thevenard-Devy, Christophe Schneider, Philippe Carl, Philippe Rondé, Stéphane Dedieu, Maxime Lehmann
Publikováno v:
Cells, Vol 10, Iss 11, p 3258 (2021)
EGFR (epidermal growth factor receptor), a member of the ErbB tyrosine kinase receptor family, is a clinical therapeutic target in numerous solid tumours. EGFR overexpression in glioblastoma (GBM) drives cell invasion and tumour progression. However,
Externí odkaz:
https://doaj.org/article/ae2c059d68384ea2b227a99f61c7dfd8
Autor:
Antoine Mousson, Marlène Legrand, Tania Steffan, Romain Vauchelles, Philippe Carl, Jean-Pierre Gies, Maxime Lehmann, Guy Zuber, Jan De Mey, Denis Dujardin, Emilie Sick, Philippe Rondé
Publikováno v:
Cancers, Vol 13, Iss 8, p 1871 (2021)
The nonreceptor tyrosine kinase FAK is a promising target for solid tumor treatment because it promotes invasion, tumor progression, and drug resistance when overexpressed. Investigating the role of FAK in human melanoma cells, we found that both in
Externí odkaz:
https://doaj.org/article/e893803ccea74043b10f99f898722f96
Publikováno v:
Cancers, Vol 11, Iss 5, p 692 (2019)
Integrins contribute to cancer progression and aggressiveness by activating intracellular signal transduction pathways and transducing mechanical tension forces. Remarkably, these adhesion receptors share common signaling networks with receptor tyros
Externí odkaz:
https://doaj.org/article/de3016d8c22e441a8121338f1485a2ff
Autor:
Tesla Yudhistira, Elisabete Cruz Da Silva, Antoine Combes, Maxime Lehmann, Andreas Reisch, Andrey S. Klymchenko
Publikováno v:
Small Methods. 7
Autor:
Stéphane Dedieu, Monique Dontenwill, Cristophe Schneider, Maxime Lehmann, Jessica Devy, Oleksandr Glushonkov, Nelly Etienne-Selloum, Marie-Cécile Mercier, Anne-Florence Blandin, Pascal Didier, Elisabete Cruz Da Silva, Laurence Choulier
Publikováno v:
Cellular and Molecular Life Sciences
Cellular and Molecular Life Sciences, Springer Verlag, 2021, 78 (6), pp.2949-2962. ⟨10.1007/s00018-020-03686-6⟩
Cellular and Molecular Life Sciences, Springer Verlag, 2021, 78 (6), pp.2949-2962. ⟨10.1007/s00018-020-03686-6⟩
Overexpression of EGFR drives glioblastomas (GBM) cell invasion but these tumours remain resistant to EGFR-targeted therapies such as tyrosine kinase inhibitors (TKIs). Endocytosis, an important modulator of EGFR function, is often dysregulated in gl
Autor:
Maxime Lehmann, Pierre Fechter, Marie-Cécile Mercier, Sophie Martin, Dominique Guenot, Nelly Etienne-Seloum, Laurence Choulier, Elisabete Cruz Da Silva, Fanny Noulet, Romain Vauchelles, Isabelle Lelong-Rebel, Monique Dontenwill, Anne-Marie Ray, Cendrine Seguin
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy-Nucleic Acids
Molecular Therapy-Nucleic Acids, Elsevier, 2019, 17, pp.63-77. ⟨10.1016/j.omtn.2019.05.006⟩
Molecular Therapy: Nucleic Acids, Vol 17, Iss, Pp 63-77 (2019)
Molecular Therapy-Nucleic Acids, Nature Publishing Group, 2019, 17, pp.63-77. ⟨10.1016/j.omtn.2019.05.006⟩
Molecular Therapy-Nucleic Acids
Molecular Therapy-Nucleic Acids, Elsevier, 2019, 17, pp.63-77. ⟨10.1016/j.omtn.2019.05.006⟩
Molecular Therapy: Nucleic Acids, Vol 17, Iss, Pp 63-77 (2019)
Molecular Therapy-Nucleic Acids, Nature Publishing Group, 2019, 17, pp.63-77. ⟨10.1016/j.omtn.2019.05.006⟩
Nucleic acid aptamers are often referred to as chemical antibodies. Because they possess several advantages, like their smaller size, temperature stability, ease of chemical modification, lack of immunogenicity and toxicity, and lower cost of product
Publikováno v:
Bioconjugate Chemistry
Bioconjugate Chemistry, American Chemical Society, 2019, 30 (1), pp.192-199. ⟨10.1021/acs.bioconjchem.8b00828⟩
Bioconjugate Chemistry, American Chemical Society, 2019, 30 (1), pp.192-199. ⟨10.1021/acs.bioconjchem.8b00828⟩
Staining of theplasmamembrane(PM) is essential in bioimaging, as it delimits the cell surface and provides various information regarding the cell morphology and status. Herein, the lipophilicity of a green emittingBODIPYfluorophore wastunedby gradual