P38 and JNK have opposing effects on persistence of in vivo leukocyte migration in zebrafish

Autor: Paul D. W. Kirk, Maxime Huvet, Jonathan R. Lamb, Michael P. H. Stumpf, Laurence Bugeon, Harriet B. Taylor, Margaret J. Dallman, Simon B. Brown, Juliane Liepe, Charlotte Barthen

Publikováno v: Immunology and Cell Biology
Taylor, H B, Liepe, J, Barthen, C, Bugeon, L, Huvet, M, Kirk, P D W, Brown, S B, Lamb, J R, Stumpf, M P H & Dallman, M J 2013, ' P38 and JNK have opposing effects on persistence of in vivo leukocyte migration in zebrafish ', Immunology and Cell Biology, vol. 91, no. 1, pp. 60-69 . https://doi.org/10.1038/icb.2012.57

The recruitment and migration of macrophages and neutrophils is an important process during the early stages of the innate immune system in response to acute injury. Transgenic pu.1:EGFP zebrafish permit the acquisition of leukocyte migration traject

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b5ab437a43590b79f1f43be12ece0a1
http://europepmc.org/articles/PMC3540327

The Evolution of the Phage Shock Protein Response System: Interplay between Protein Function, Genomic Organization, and System Function

Autor: Goran Jovanovic, Christoph Engl, Tina Toni, John W. Pinney, Thomas Thorne, Xia Sheng, Maxime Huvet, Martin Buck, Michael P. H. Stumpf

Publikováno v: Molecular Biology and Evolution

Sensing the environment and responding appropriately to it are key capabilities for the survival of an organism. All extant organisms must have evolved suitable sensors, signaling systems, and response mechanisms allowing them to survive under the co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74c915b5f071308a2b75f6d751c2ba02
https://doi.org/10.1093/molbev/msq301

The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae

Autor: David H. Ardell, Björn Canbäck, Siv G. E. Andersson, A. Carolin Frank, Martin Holmberg, Ann-Sofie Eriksson, Bernard La Scola, Cecilia Alsmark, Scott A. Handley, E. Olof Karlberg, A. Kristina Näslund, Boris-Antoine Legault, Maxime Huvet

Publikováno v: Proceedings of the National Academy of Sciences. 101:9716-9721

We present the complete genomes of two human pathogens, Bartonella quintana (1,581,384 bp) and Bartonella henselae (1,931,047 bp). The two pathogens maintain several similarities in being transmitted by insect vectors, using mammalian reservoirs, inf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf98c209ed542c8deae414d3bd7eb35e
https://doi.org/10.1073/pnas.0305659101

Calibrating spatio-temporal models of leukocyte dynamics against in vivo live-imaging data using approximate Bayesian computation

Autor: Laurence Bugeon, Michael P. H. Stumpf, Thomas Thorne, Juliane Liepe, Harriet B. Taylor, Margaret J. Dallman, Jonathan R. Lamb, Maxime Huvet, Chris P. Barnes

Publikováno v: Integrative biology : quantitative biosciences from nano to macro. 4(3)

In vivo studies allow us to investigate biological processes at the level of the organism. But not all aspects of in vivo systems are amenable to direct experimental measurements. In order to make the most of such data we therefore require statistica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15f208f13dfb1b7b3faf53ce41e5e51a
https://pubmed.ncbi.nlm.nih.gov/22327539

From Qualitative Data to Quantitative Models: Analysis of the Phage Shock Protein Response in Escherichia coli

Autor: Tina Toni, Maxime Huvet, Goran Jovanovic, Michael P. H. Stumpf, Martin Buck

Publikováno v: BMC Systems Biology
BMC
BMC Systems Biology, Vol 5, Iss 1, p 69 (2011)

Background Bacteria have evolved a rich set of mechanisms for sensing and adapting to adverse conditions in their environment. These are crucial for their survival, which requires them to react to extracellular stresses such as heat shock, ethanol tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4759104a6e5b5b7ed2efa5ed9a28bcf5
http://hdl.handle.net/10044/1/27302