Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Maxime Hebrard"'
Autor:
Joanna Hui Juan Tan, Zhihui Li, Mar Gonzalez Porta, Ramesh Rajaby, Weng Khong Lim, Ye An Tan, Rodrigo Toro Jimenez, Renyi Teo, Maxime Hebrard, Jack Ling Ow, Shimin Ang, Justin Jeyakani, Yap Seng Chong, Tock Han Lim, Liuh Ling Goh, Yih Chung Tham, Khai Pang Leong, Calvin Woon Loong Chin, SG10K_Health Consortium, Sonia Davila, Neerja Karnani, Ching-Yu Cheng, John Chambers, E. Shyong Tai, Jianjun Liu, Xueling Sim, Wing Kin Sung, Shyam Prabhakar, Patrick Tan, Nicolas Bertin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Structural variants (SVs) are significant contributors to inter-individual genetic variation associated with traits and diseases. Current SV studies using whole-genome sequencing (WGS) have a largely Eurocentric composition, with little know
Externí odkaz:
https://doaj.org/article/bb56de9b54524700a6c80797234f227e
Autor:
Sock Hoai Chan, Yasmin Bylstra, Jing Xian Teo, Jyn Ling Kuan, Nicolas Bertin, Mar Gonzalez-Porta, Maxime Hebrard, Roberto Tirado-Magallanes, Joanna Hui Juan Tan, Justin Jeyakani, Zhihui Li, Jin Fang Chai, Yap Seng Chong, Sonia Davila, Liuh Ling Goh, Eng Sing Lee, Eleanor Wong, Tien Yin Wong, SG10K_Health Consortium, Shyam Prabhakar, Jianjun Liu, Ching-Yu Cheng, Birgit Eisenhaber, Neerja Karnani, Khai Pang Leong, Xueling Sim, Khung Keong Yeo, John C. Chambers, E-Shyong Tai, Patrick Tan, Saumya S. Jamuar, Joanne Ngeow, Weng Khong Lim
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Clinically significant genetic variation in Asian populations is under-characterized. Here, the authors show the diversity in prevalence and spectrum of human disease and pharmacogenetic variants in a multi-ethnic Asian population.
Externí odkaz:
https://doaj.org/article/117b09c793b9435cbcba4527a4883feb
Autor:
Chih Chuan Shih, Jieqi Chen, Ai Shan Lee, Nicolas Bertin, Maxime Hebrard, Chiea Chuen Khor, Zheng Li, Joanna Hui Juan Tan, Wee Yang Meah, Su Qin Peh, Shi Qi Mok, Kar Seng Sim, Jianjun Liu, Ling Wang, Eleanor Wong, Jingmei Li, Aung Tin, Ching-Yu Cheng, Chew-Kiat Heng, Jian-Min Yuan, Woon-Puay Koh, Seang Mei Saw, Yechiel Friedlander, Xueling Sim, Jin Fang Chai, Yap Seng Chong, Sonia Davila, Liuh Ling Goh, Eng Sing Lee, Tien Yin Wong, Neerja Karnani, Khai Pang Leong, Khung Keong Yeo, John C. Chambers, Su Chi Lim, Rick Siow Mong Goh, Patrick Tan, Rajkumar Dorajoo
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106546- (2023)
Summary: Genomic researchers increasingly utilize commercial cloud service providers (CSPs) to manage data and analytics needs. CSPs allow researchers to grow Information Technology (IT) infrastructure on demand to overcome bottlenecks when combining
Externí odkaz:
https://doaj.org/article/3a05ca171fb2408194c45da5d91f3fb5
Autor:
Ananya Pal, Jia Yu Leung, Gareth Chin Khye Ang, Vinay Kumar Rao, Luca Pignata, Huey Jin Lim, Maxime Hebrard, Kenneth TE Chang, Victor KM Lee, Ernesto Guccione, Reshma Taneja
Publikováno v:
eLife, Vol 9 (2020)
Wnt signaling is downregulated in embryonal rhabdomyosarcoma (ERMS) and contributes to the block of differentiation. Epigenetic mechanisms leading to its suppression are unknown and could pave the way toward novel therapeutic modalities. We demonstra
Externí odkaz:
https://doaj.org/article/db70951a46d04ec4b8dcef9cb836464b
Autor:
Khee Chian Jason Chin, Todd Duane Taylor, Maxime Hebrard, Kogaan Anbalagan, Marjan Ganjali Dashti, Kia Kien Phua
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-9 (2017)
Abstract Background Typhoid fever is an acute systemic infection of humans caused by Salmonella enterica subspecies enterica serovar Typhi (S. Typhi). In chronic carriers, the bacteria survive the harsh environment of the gallbladder by producing bio
Externí odkaz:
https://doaj.org/article/0dfd9effb7ca43f1aa8eca5e697e0445
Autor:
Maxime Hebrard, Todd D Taylor
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0158261 (2016)
Metagenomic samples can contain hundreds or thousands of different species. The most common method to identify these species is to sequence the samples and then classify the reads to nodes along a phylogenic tree. Linear representations of trees with
Externí odkaz:
https://doaj.org/article/b5b5814cb9c848b6a68370c86fd8174a
Autor:
Sebastian Maurer-Stroh, Ashar Malik, Dimitar Kenanov, Cheng-Shoong Chong, Mert Burak Ozturk, Maxime Hebrard, Ying Swan Ho, Zhenxun Wang, Vachiranee Limviphuvadh, Jhoann Miyajima, Roberto Magallanes, Xueling Sim, Jin Fang Chai, Sonia Davila, Khung Keong Yeo, Khai Pang Leong, Liuh Ling Goh, Neerja Karnani, Johan Gunnar Eriksson, Ching-Yu Cheng, Tien Wong, Marie Loh, Rinkoo Dalan, Chiea Chuen Khor, Guo-Liang Chew, Weng Khong Lim, Joanne Ngeow, John Chambers, E Shyong Tai, Nicolas Bertin, Chris Soon Heng Tan, Judice Koh, Patrick Tan, Chandra Verma
One of the promises of precision medicine is to understand and act on inter-individual genetic differences in drug responses. SNPdrug3D contains the complete genomic landscape of missense single nucleotide variants (SNV) across the human proteome and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dea066a53ae7a448d8ac2483b836a175
https://doi.org/10.21203/rs.3.rs-2377190/v1
https://doi.org/10.21203/rs.3.rs-2377190/v1
Autor:
Chih Chuan Shih, Jieqi Chen, Ai Shan Lee, Nicolas Bertin, Maxime Hebrard, Chiea Chuen Khor, Zheng Li, Joanna Hui Juan Tan, Wee Yang Meah, Su Qin Peh, Shi Qi Mok, Kar Seng Sim, Jianjun Liu, Ling Wang, Eleanor Wong, Jingmei Li, Aung Tin, Ching-Yu Cheng, Chew-Kiat Heng, Jian-Min Yuan, Woon-Puay Koh, Seang Mei Saw, Yechiel Friedlander, Xueling Sim, Jin Fang Chai, Yap Seng Chong, Sonia Davila, Liuh Ling Goh, Eng Sing Lee, Tien Yin Wong, Neerja Karnani, Khai Pang Leong, Khung Keong Yeo, John C Chambers, Su Chi Lim, Rick Siow Mong Goh, Patrick Tan, Rajkumar Dorajoo
Genomic researchers are increasingly utilizing commercial cloud platforms (CCPs) to manage their data and analytics needs. Commercial clouds allow researchers to grow their storage and analytics capacity on demand, keeping pace with expanding project
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7baa4290d2421ab94cfd137ed53b211d
https://doi.org/10.1101/2022.10.27.514127
https://doi.org/10.1101/2022.10.27.514127
Autor:
Jia Yu Leung, Luca Pignata, Victor Kwan Min Lee, Reshma Taneja, Gareth Chin Khye Ang, Ernesto Guccione, Ananya Pal, Vinay Kumar Rao, Kenneth Te Chang, Maxime Hebrard, Huey Jin Lim
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Wnt signaling is downregulated in embryonal rhabdomyosarcoma (ERMS) and contributes to the block of differentiation. Epigenetic mechanisms leading to its suppression are unknown and could pave the way toward novel therapeutic modalities. We demonstra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55d196768f4fe347a265e21324806f95
http://europepmc.org/articles/PMC7728445
http://europepmc.org/articles/PMC7728445
Autor:
Ananya Pal, Jia Yu Leung, Luca Pignata, Vinay Kumar Rao, Ernesto Guccione, Reshma Taneja, Kenneth Te Chang, Huey Jin Lim, Gareth Chin Khye Ang, Maxime Hebrard, Victor Kwan Min Lee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4776a5701073f49be1796c53ee0bfd6d
https://doi.org/10.7554/elife.57683.sa2
https://doi.org/10.7554/elife.57683.sa2