Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Maxime Hallé"'
Autor:
Jerry Pelletier, Philip G. Williams, Yasuhiro Igarashi, John A. Porco, Maxime Hallé, Dylan Pelletier, Brian O. Bachmann, David E. Williams, Abimael D. Rodríguez, Francis Robert, Neha Sawhney, Regina Cencic, Raymond J. Andersen, Jutta Steinberger, Brigitte Kopp
Publikováno v:
Cell Chem Biol
Our inability to effectively “drug” targets such as MYC for therapeutic purposes requires the development of new approaches. We report on the implementation of a phenotype-based assay for monitoring MYC expression in multiple myeloma cells. The o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a109a851cb88b0eb894345879813d8df
https://doi.org/10.1016/j.chembiol.2019.02.007
https://doi.org/10.1016/j.chembiol.2019.02.007
Autor:
Adam M. Scott, Géraldine Miquel, Melanie J. Chagnon, Anita Hall, Maxime Hallé, Masaharu Noda, Andreas Bikfalvi, Emily Ayoub, Michel L. Tremblay
Publikováno v:
Journal of Biological Chemistry. 288:25739-25748
PTP-PEST is a cytosolic ubiquitous protein tyrosine phosphatase (PTP) that contains, in addition to its catalytic domain, several protein-protein interaction domains that allow it to interface with several signaling pathways. Among others, PTP-PEST i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7ecb6a33cf220afaaac86c40292226e
https://doi.org/10.1074/jbc.m113.501007
https://doi.org/10.1074/jbc.m113.501007
Publikováno v:
Cell Cycle. 6:2773-2781
Apoptosis is a precisely controlled physiological mechanism that is required for the elimination of cells during embryonic development, in response to stress and infection as well as in the maintenance of homeostasis. Since the outcome of several of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29e02b550bca4bdf54da3177c7c19f2b
https://doi.org/10.4161/cc.6.22.4926
https://doi.org/10.4161/cc.6.22.4926
Autor:
Ying-Chih Liu, Christophe Blanchetot, Jean-François Théberge, Annie Bourdeau, Maxime Hallé, Serge Hardy, Michel L. Tremblay, Tzu-Ching Meng
Publikováno v:
Molecular and Cellular Biology. 27:1172-1190
The protein tyrosine phosphatase PEST (PTP-PEST) is involved in the regulation of the actin cytoskeleton. Despite the emerging functions attributed to both PTPs and the actin cytoskeleton in apoptosis, the involvement of PTP-PEST in apoptotic cell de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21d16c70bdf0a3d4d5ea747c4e1d2682
https://doi.org/10.1128/mcb.02462-05
https://doi.org/10.1128/mcb.02462-05
Autor:
Eva Nievergall, Martin Lackmann, Carmen Llerena, Maxime Hallé, Lakmali Atapattu, Mariam Mansour, Peter W. Janes, Kristina Gegenbauer, Michel L. Tremblay
Publikováno v:
Journal of cell science. 129(2)
Eph receptors and their corresponding membrane-bound ephrin ligands regulate cell positioning and establish tissue patterns during embryonic and oncogenic development. Emerging evidence suggests that assembly of polymeric Eph signalling clusters reli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a77a37451f780120a649ead09dbc4ad2
https://pubmed.ncbi.nlm.nih.gov/26644181
https://pubmed.ncbi.nlm.nih.gov/26644181
Autor:
Michael C. Brown, David A. Tumbarello, Maxime Hallé, Michel L. Tremblay, Christopher E. Turner, Jennifer S. Jamieson
Publikováno v:
Journal of Cell Science. 118:5835-5847
The tyrosine phosphatase PTP-PEST has been implicated in the regulation of cell spreading and migration through dephosphorylation of focal adhesion proteins and inhibition of Rac GTPase activity. The focal adhesion adaptor protein paxillin is also ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33d6573343a8f14d531630884036d142
https://doi.org/10.1242/jcs.02693
https://doi.org/10.1242/jcs.02693
Autor:
Peter Thériault, Christopher W Cluff, Paul Préfontaine, Maxime Hallé, Jean-Philippe Michaud, Serge Rivest, Rachel Jodoin, Daniel Larocque, Remi Palmantier, Vincent Brichard, Anthony Pilorget, Mohammed Filali, Anne-Marie Lanteigne, Pascale Tribout-Jover, Antoine Lampron
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 110(5)
Alzheimer’s disease (AD) is the most common cause of dementia worldwide. The pathogenesis of this neurodegenerative disease, currently without curative treatment, is associated with the accumulation of amyloid β (Aβ) in brain parenchyma and cereb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3954eac861fa4d38a5e38686dd11cbb
https://pubmed.ncbi.nlm.nih.gov/23746134
https://pubmed.ncbi.nlm.nih.gov/23746134
Autor:
Michel L. Tremblay, Robert McMaster, Martin Olivier, Maxime Hallé, Maria Adelaida Gomez, Irazú Contreras
Publikováno v:
Science signaling. 2(90)
With more than 12 million people affected worldwide, 2 million new cases occurring per year, and the rapid emergence of drug resistance and treatment failure, leishmaniasis is an infectious disease for which research on drug and vaccine development,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a7a8b42a36d4cf377ad8b6da5335986
https://pubmed.ncbi.nlm.nih.gov/19797268
https://pubmed.ncbi.nlm.nih.gov/19797268
Autor:
Kenneth Aldape, Michel L. Tremblay, Zhimin Lu, David H. Hawke, Xiang Gao, Jie He, Yan Xia, Melanie H. Cobb, Maxime Hallé, Yanhua Zheng, Keping Xie, Xiao Zhen Zhou
Activated Ras has been found in many types of cancer. However, the mechanism underlying Ras-promoted tumor metastasis remains unclear. We demonstrate here that activated Ras induces tyrosine dephosphorylation and inhibition of FAK mediated by the Ras
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbebae50ec7012aa9011bfb34ba0f48c
https://europepmc.org/articles/PMC2715139/
https://europepmc.org/articles/PMC2715139/
Autor:
Matthew Stuible, Maxime Hallé, W. Robert McMaster, Hidehisa Shimizu, Martin Olivier, Maria Adelaida Gomez, Michel L. Tremblay
The Leishmania parasite is a widespread disease threat in tropical areas, causing symptoms ranging from skin lesions to death. Leishmania parasites typically invade macrophages but are also capable of infecting fibroblasts, which may serve as a reser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3703f85c881113657af0ec2a747a1c32
https://europepmc.org/articles/PMC2652307/
https://europepmc.org/articles/PMC2652307/