Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Maxime Gueguinou"'
Autor:
Marion Papin, Delphine Fontaine, Caroline Goupille, Sandy Figiel, Isabelle Domingo, Michelle Pinault, Cyrille Guimaraes, Nina Guyon, Pierre François Cartron, Patrick Emond, Antoine Lefevre, Maxime Gueguinou, David Crottès, Paul-Alain Jaffrès, Lobna Ouldamer, Karine Maheo, Gaëlle Fromont, Marie Potier-Cartereau, Philippe Bougnoux, Aurélie Chantôme, Christophe Vandier
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 5, Pp 100544- (2024)
SK3 channels are potassium channels found to promote tumor aggressiveness. We have previously demonstrated that SK3 is regulated by synthetic ether lipids, but the role of endogenous ether lipids is unknown. Here, we have studied the role of endogeno
Externí odkaz:
https://doaj.org/article/c60252b33184451bac3e20c91baf77d9
Autor:
Trayambak Pathak, Maxime Gueguinou, Vonn Walter, Celine Delierneux, Martin T Johnson, Xuexin Zhang, Ping Xin, Ryan E Yoast, Scott M Emrich, Gregory S Yochum, Israel Sekler, Walter A Koltun, Donald L Gill, Nadine Hempel, Mohamed Trebak
Publikováno v:
eLife, Vol 12 (2023)
Externí odkaz:
https://doaj.org/article/bacfc4e9fb7f4dd8bf3716d520a39baf
A calcium/cAMP signaling loop at the ORAI1 mouth drives channel inactivation to shape NFAT induction
Autor:
Xuexin Zhang, Trayambak Pathak, Ryan Yoast, Scott Emrich, Ping Xin, Robert M. Nwokonko, Martin Johnson, Shilan Wu, Céline Delierneux, Maxime Gueguinou, Nadine Hempel, James W. Putney, Donald L. Gill, Mohamed Trebak
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
ORAI1 constitutes the store-operated Ca2+ release-activated Ca2+ (CRAC) channel, but how this channel is turned off through Ca2+-dependent inactivation (CDI) remained unclear. Here the authors identify a spatially-restricted Ca2+/cAMP signaling cross
Externí odkaz:
https://doaj.org/article/273145bab6b34b6fac4674fdd0ecc38c
Autor:
Trayambak Pathak, Maxime Gueguinou, Vonn Walter, Celine Delierneux, Martin T Johnson, Xuexin Zhang, Ping Xin, Ryan E Yoast, Scott M Emrich, Gregory S Yochum, Israel Sekler, Walter A Koltun, Donald L Gill, Nadine Hempel, Mohamed Trebak
Publikováno v:
eLife, Vol 9 (2020)
Despite the established role of mitochondria in cancer, the mechanisms by which mitochondrial Ca2+ (mtCa2+) regulates tumorigenesis remain incompletely understood. The crucial role of mtCa2+ in tumorigenesis is highlighted by altered expression of pr
Externí odkaz:
https://doaj.org/article/5281232761db416a876d72cbe79942a1
Autor:
Maryne Dupuy, Maxime Gueguinou, Anaïs Postec, Régis Brion, Robel Tesfaye, Mathilde Mullard, Laura Regnier, Jérôme Amiaud, Marie Potier-Cartereau, Aurélie Chantôme, Bénédicte Brounais-Le Royer, Marc Baud’huin, Steven Georges, François Lamoureux, Benjamin Ory, Olivier Delattre, Françoise Rédini, Christophe Vandier, Franck Verrecchia
Ewing sarcoma (ES) is characterized by chimeric fusion proteins, which act as oncogenes. Over the last decade, patient survival has not increased, especially for high risk patients. Knowing that ion channels are studied for their implication in tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf5f6ff0ab756b2938f46bf90990c438
https://doi.org/10.1101/2023.04.24.538050
https://doi.org/10.1101/2023.04.24.538050
Autor:
Sarah Proteau, Imène Krossa, Chrystel Husser, Maxime Guéguinou, Federica Sella, Karine Bille, Marie Irondelle, Mélanie Dalmasso, Thibault Barouillet, Yann Cheli, Céline Pisibon, Nicole Arrighi, Sacha Nahon-Estève, Arnaud Martel, Lauris Gastaud, Sandra Lassalle, Olivier Mignen, Patrick Brest, Nathalie M Mazure, Frédéric Bost, Stéphanie Baillif, Solange Landreville, Simon Turcotte, Dan Hasson, Saul Carcamo, Christophe Vandier, Emily Bernstein, Laurent Yvan-Charvet, Mitchell P Levesque, Robert Ballotti, Corine Bertolotto, Thomas Strub
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 9, Pp 2262-2267 (2024)
Externí odkaz:
https://doaj.org/article/4674eb9ca9f241b4a3996ff03dc79709
Autor:
Maryne Dupuy, Maxime Gueguinou, Mathilde Mullard, Robel Tesfaye, Jerome Amiaud, Sarah Morice, Benjamin Ory, Francoise Redini, Christophe Vandier, Franck Verrecchia
Publikováno v:
Cancer Research. 82:6267-6267
Ewing sarcoma (ES) is the second most common primary bone tumor among children and teenagers. The survival rate for patients is about 70%, but drops dramatically to less than 30% when metastases are present at diagnostic. The current treatment consis
Autor:
Marie, Potier-Cartereau, William, Raoul, Gunther, Weber, Karine, Mahéo, Raphael, Rapetti-Mauss, Maxime, Gueguinou, Paul, Buscaglia, Caroline, Goupille, Nelig, Le Goux, Souleymane, Abdoul-Azize, Thierry, Lecomte, Gaëlle, Fromont, Aurélie, Chantome, Olivier, Mignen, Olivier, Soriani, Christophe, Vandier
Publikováno v:
Reviews of physiology, biochemistry and pharmacology. 183
The intracellular Ca
LKB1‐SIK2 loss drives uveal melanoma proliferation and hypersensitivity to SLC8A1 and ROS inhibition
Autor:
Sarah Proteau, Imène Krossa, Chrystel Husser, Maxime Guéguinou, Federica Sella, Karine Bille, Marie Irondelle, Mélanie Dalmasso, Thibault Barouillet, Yann Cheli, Céline Pisibon, Nicole Arrighi, Sacha Nahon‐Estève, Arnaud Martel, Lauris Gastaud, Sandra Lassalle, Olivier Mignen, Patrick Brest, Nathalie M Mazure, Frédéric Bost, Stéphanie Baillif, Solange Landreville, Simon Turcotte, Dan Hasson, Saul Carcamo, Christophe Vandier, Emily Bernstein, Laurent Yvan‐Charvet, Mitchell P Levesque, Robert Ballotti, Corine Bertolotto, Thomas Strub
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 12, Pp n/a-n/a (2023)
Abstract Metastatic uveal melanomas are highly resistant to all existing treatments. To address this critical issue, we performed a kinome‐wide CRISPR‐Cas9 knockout screen, which revealed the LKB1‐SIK2 module in restraining uveal melanoma tumor
Externí odkaz:
https://doaj.org/article/1a3e75bad0684eebb8afbad93d505cd9
Autor:
Gabriel, Bidaux, Dmitri, Gordienko, George, Shapovalov, Valerio, Farfariello, Anne-Sophie, Borowiec, Oksana, Iamshanova, Loic, Lemonnier, Maxime, Gueguinou, Roseline, Guibon, Gaelle, Fromont, Mélanie, Paillard, Yves, Gouriou, Christophe, Chouabe, Etienne, Dewailly, Dimitra, Gkika, Pilar, López-Alvarado, J, Carlos Menéndez, Laurent, Héliot, Christian, Slomianny, Natalia, Prevarskaya
Publikováno v:
Biochimica et biophysica acta. Molecular cell research. 1865(7)
Calcium (Ca