Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Maxime Lampilas"'
Autor:
Valérie Steier, Catherine Seys, Maxime Lampilas, Claudine Dupuis-Hamelin, Carole Delachaume, Michele Guitton, Thérèse Stachyra, Alain Bonnefoy, Monique Fairley
Publikováno v:
Journal of Antimicrobial Chemotherapy. 54:410-417
OBJECTIVES Production of beta-lactamases is the main mechanism of beta-lactam resistance in Gram-negative bacteria. Despite the current use of clavulanic acid, sulbactam and tazobactam, the prevalence of class A and class C enzymes is increasing worl
Autor:
Lothar Hennig, Matthias Findeisen, Maxime Lampilas, Sabine Giesa, Peter Welzel, Stefan Vogel, Katherina Stembera, Claire Tillier, Christian Bonhomme
Publikováno v:
Tetrahedron. 57:4147-4160
From a moenomycin A glycolic aldehyde degradation product lacking the chromophore unit and most of the lipid part, a number of amines were prepared by reductive amination. Their interaction with artificial membranes as well as their transglycosylase
Autor:
Lothar Hennig, Peter Welzel, Katherina Stembera, Sabine Giesa, Matthias Findeisen, Stefan Vogel, Maxime Lampilas
Publikováno v:
Vogel, S, K., S, L., H, M., F, S., G, P., W & M., L 2001, ' Moenomycin analogues with modified lipid side chains from indium-mediated Barbier-type reactions. ', Tetrahedron, vol. 57, no. 19, pp. 4139-4146 .
University of Southern Denmark
University of Southern Denmark
From moenomycin A both the chromophore part and the lipid side chain were degraded by ozonolysis to give an analogue with a glycolaldehyde unit in 2-position of the glyceric acid moiety. The aldehyde was converted to a number of homoallylic alcohols
Autor:
Jean van Heijenoort, Maxime Lampilas, Jozsef Aszodi, Jozef Van Beeumen, Jean-Marie Ghuysen, Tushar K. Ghosh, Mohammed Terrak, Juan A. Ayala, Martine Nguyen-Distèche
Publikováno v:
Molecular Microbiology. 34:350-364
The penicillin-binding protein (PBP) 1b of Escherichia coli catalyses the assembly of lipid-transported N-acetyl glucosaminyl-beta-1, 4-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-(L)-meso-diaminopimelyl+ ++- (L)-D-alanyl-D-alanine disaccharide pentap
Autor:
Matthias Findeisen, Dietrich Müller, Markus Astrid, Lothar Hennig, Jean van Heijenoort, Maxime Lampilas, Peter Welzel, Naser El-Abadla
Publikováno v:
Tetrahedron. 55:699-722
Two disaccharide analogues 1b and 17a of moenomycin A have been synthesized and their antibiotic and transglycosylase-inhibiting properties have been determined. The results permit for the first time to arrive at a general view of the structural requ
Autor:
Lothar Hennig, Matthias Findeisen, Dietrich Müller, Olaf Ritzeler, Guy Lemoine, Jean van Heijenoort, Astrid Markus, Maxime Lampilas, Peter Welzel
Publikováno v:
Tetrahedron. 53:1675-1694
A trisaccharide analogue of moenomycin A, 9a, has been synthesized and has found to be antibiotically inactive. This compound differs from an active compound, 9b, solely by the exchange NHAc→OH in unit C. A binding model for moenomycin-type transgl
Autor:
Olaf Ritzeler, Matthias Findeisen, Astrid Markus, Lothar Hennig, G. Lemoine, Maxime Lampilas, Peter Welzel, D. Mueller, J van Heijenoort
Publikováno v:
ChemInform. 28
Autor:
Matthias Findeisen, Lothar Hennig, D. Mueller, Markus Astrid, Naser El-Abadla, Peter Welzel, Jean van Heijenoort, Maxime Lampilas
Publikováno v:
ChemInform. 30
Autor:
Robert Lett, Maxime Lampilas
Publikováno v:
Tetrahedron Letters. 33:773-776
The first total synthesis of Monocillin I related macrolides has been achieved by a convergent and stereospecific route involving the palladium - catalyzed coupling of a functionnalized chiral vinylstannane with the appropriate dimethoxy bromomethyl
Autor:
Maxime Lampilas, Robert Lett
Publikováno v:
Tetrahedron Letters. 33:777-780
The first total syntheses of the antifungal resorcylic macrolides Monocillin I and Monorden (or Radicicol) have been achieved by a convergent stereospecific route. TBDMS phenol ethers were found to be suitable for all the scheme and were removed in t