Epithelial Label-Retaining Cells Are Absent during Tooth Cycling in Salmo salar and Polypterus senegalus.

Autor: Sam Vandenplas, Maxime Willems, P Eckhard Witten, Tom Hansen, Per Gunnar Fjelldal, Ann Huysseune

Publikováno v: PLoS ONE, Vol 11, Iss 4, p e0152870 (2016)

The Atlantic salmon (Salmo salar) and African bichir (Polypterus senegalus) are both actinopterygian fish species that continuously replace their teeth without the involvement of a successional dental lamina. Instead, they share the presence of a mid

Externí odkaz: https://doaj.org/article/1c74b99920a0407ab6a3562f91e41e52

Planarians Customize Their Stem Cell Responses Following Genotoxic Stress as a Function of Exposure Time and Regenerative State

Autor: Karen Smeets, Andromeda Van Roten, Carmen Franken, Niels Hellings, Gudrun Koppen, An-Sofie Stevens, Nicky Pirotte, Annelies Wouters, Tom Artois, Maxime Willems, Jan-Pieter Ploem, Michelle Plusquin

Aiming to in vivo characterize the responses of pluripotent stem cells and regenerative tissues to carcinogenic stress, we employed the highly regenerative organism Schmidtea mediterranea. Its broad regenerative capacities are attributable to a large

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b62232cdb5eca0701b9b5829bb44bd5
http://hdl.handle.net/1942/26279

Toxicity profiles and solvent-toxicant interference in the planarianSchmidtea mediterraneaafter dimethylsulfoxide (DMSO) exposure

Autor: Nicky Pirotte, Maxime Willems, Karen Smeets, An-Sofie Stevens, Thomas Neyens, Michelle Plusquin, Tom Artois

Publikováno v: Journal of Applied Toxicology. 35:319-326

To investigate hydrophobic test compounds in toxicological studies, solvents like dimethylsulfoxide (DMSO) are inevitable. However, using these solvents, the interpretation of test compound-induced responses can be biased. DMSO concentration guidelin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a786da851e7179ec436edd3dc4d002e6
https://doi.org/10.1002/jat.3011

Redox-Related Mechanisms to Rebalance Cancer-Deregulated Cell Growth

Autor: Nicky Pirotte, Frank Van Belleghem, Andromeda Van Roten, Maxime Willems, Tom Artois, An-Sofie Stevens, Annelies Wouters, Ann Cuypers, Karen Smeets

Publikováno v: Stevens, A-S, Pirotte, N, Wouters, A, Van Roten, A, Van Belleghem, F, Willems, M, Cuypers, A, Artois, T & Smeets, K 2016, ' Redox-Related Mechanisms to Rebalance Cancer-Deregulated Cell Growth ', Current Drug Targets, vol. 17, no. 12, pp. 1414-1437 . https://doi.org/10.2174/1389450116666150506112817

A delicate balance exists between the process of carcinogenesis and tissue regeneration. A number of malignant tumours are considered the outcome of an impaired or incomplete regeneration process, resulting in persistently dividing cells. Regeneratio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c38ad526e2946766f70ee7a2f807d3b
https://hdl.handle.net/1820/1249b87b-0d55-4a53-823e-c1b9106ed971

Dual BrdU-PCNA immunodetection of proliferative cells in dental and orofacial tissues of teleosts

Autor: Ann Huysseune, Sam Vandenplas, Maxime Willems

Publikováno v: Journal of Applied Ichthyology. 28:336-340

Summary We have developed a protocol for simultaneous detection of BrdU and PCNA on paraffin sections of teleost tissues and have tested it successfully on dental and orofacial tissues of Atlantic salmon (Salmo salar) and zebrafish (Danio rerio). By

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3ed8ecb9decfb37e2fc7c3c318aa448a
https://doi.org/10.1111/j.1439-0426.2012.02003.x