Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Maxim V C, Greenberg"'
Autor:
Julien Richard Albert, Toshihiro Kobayashi, Azusa Inoue, Ana Monteagudo-Sánchez, Soichiro Kumamoto, Tomoya Takashima, Asuka Miura, Mami Oikawa, Fumihito Miura, Shuji Takada, Masumi Hirabayashi, Keegan Korthauer, Kazuki Kurimoto, Maxim V. C. Greenberg, Matthew Lorincz, Hisato Kobayashi
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-32 (2023)
Abstract Background Genomic imprinting affects gene expression in a parent-of-origin manner and has a profound impact on complex traits including growth and behavior. While the rat is widely used to model human pathophysiology, few imprinted genes ha
Externí odkaz:
https://doaj.org/article/d2b4346a6d9745bcb4ddefb8b94050fb
Autor:
Line Manceau, Julien Richard Albert, Pier-Luigi Lollini, Maxim V C Greenberg, Pascale Gilardi-Hebenstreit, Vanessa Ribes
Publikováno v:
PLoS Genetics, Vol 18, Iss 5, p e1009782 (2022)
The hallmarks of the alveolar subclass of rhabdomyosarcoma are chromosomal translocations that generate chimeric PAX3-FOXO1 or PAX7-FOXO1 transcription factors. Overexpression of either PAX-FOXO1s results in related cell transformation in animal mode
Externí odkaz:
https://doaj.org/article/f1a9fa02e04e414f987d656653b2044c
Autor:
Maxim V. C. Greenberg
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Vertebrate genomes are marked by notably high levels of 5-cytosine DNA methylation (5meC). The clearest function of DNA methylation among members of the subphylum is repression of potentially deleterious transposable elements (TEs). However, enrichme
Externí odkaz:
https://doaj.org/article/d617f32311584e9b9f8ce92247e8b720
Autor:
Agnès Dubois, Loris Vincenti, Almira Chervova, Maxim V. C. Greenberg, Sandrine Vandormael-Pournin, Déborah Bourc'his, Michel Cohen-Tannoudji, Pablo Navarro
Publikováno v:
Development (Cambridge, England)
Development (Cambridge, England), 2022, 149 (17), pp.dev201074. ⟨10.1242/dev.201074⟩
Development (Cambridge, England), 2022, 149 (17), pp.dev201074. ⟨10.1242/dev.201074⟩
Mouse embryonic stem cells have an inherent propensity to explore gene regulatory states associated with either self-renewal or differentiation. This property depends on ERK, which downregulates pluripotency genes such as Nanog. Here, we aimed at ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9584fd7f27b37a2a363566bb3518f4f8
https://hal-pasteur.archives-ouvertes.fr/pasteur-03796516
https://hal-pasteur.archives-ouvertes.fr/pasteur-03796516
Autor:
Julien Richard Albert, Maxim V. C. Greenberg, Vanessa Ribes, Pascale Gilardi-Hebenstreit, Line Manceau, Pier Luigi Lollini
Publikováno v:
PLoS genetics. 18(5)
The hallmarks of the alveolar subclass of rhabdomyosarcoma are chromosomal translocations that generate chimeric PAX3-FOXO1 or PAX7-FOXO1 transcription factors. Both PAX-FOXO1s result in related cell transformation in animal models, but both mutation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ef731d78a819fd8bdbe183537f84d4e
https://pubmed.ncbi.nlm.nih.gov/35604932
https://pubmed.ncbi.nlm.nih.gov/35604932
Publikováno v:
Nature Genetics
Nature Genetics, Nature Publishing Group, 2021, 53 (4), pp.427-429. ⟨10.1038/s41588-021-00833-y⟩
Nature Genetics, Nature Publishing Group, 2021, 53 (4), pp.427-429. ⟨10.1038/s41588-021-00833-y⟩
International audience; Polycomb-group proteins assemble into two primary complexes-Polycomb repressive complex (PRC) 1 and 2-that safeguard cell fate by repressing gene transcription. Two new studies explore the PRC1 landscape during the transition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34a20ce48306c8ecdd13578bed6df97a
https://doi.org/10.1038/s41588-021-00833-y
https://doi.org/10.1038/s41588-021-00833-y
Autor:
Maxim V. C. Greenberg, Déborah Bourc'his, Daan Noordermeer, Aurélie Teissander, Marius Walter
SUMMARYDuring early mammalian development, the genome undergoes profound transitions in chromatin states, topological organization and recruitment ofcisregulatory factors involved in transcriptional control. How these three layers of gene regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f072a9c81b02317ba32c3f50f23c305
https://halshs.archives-ouvertes.fr/halshs-03437256
https://halshs.archives-ouvertes.fr/halshs-03437256
Publikováno v:
Nature Reviews Molecular Cell Biology
Nature Reviews Molecular Cell Biology, Nature Publishing Group, 2019, 20 (10), pp.590-607. ⟨10.1038/s41580-019-0159-6⟩
Nature Reviews Molecular Cell Biology, Nature Publishing Group, 2019, 20 (10), pp.590-607. ⟨10.1038/s41580-019-0159-6⟩
DNA methylation is of paramount importance for mammalian embryonic development. DNA methylation has numerous functions: it is implicated in the repression of transposons and genes, but is also associated with actively transcribed gene bodies and, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a72c9594deb40f43fae327b3aded4cc
https://doi.org/10.1038/s41580-019-0159-6
https://doi.org/10.1038/s41580-019-0159-6
Autor:
Maxim V C Greenberg, Angelique Deleris, Christopher J Hale, Ao Liu, Suhua Feng, Steven E Jacobsen
Publikováno v:
PLoS Genetics, Vol 9, Iss 11, p e1003946 (2013)
DNA methylation is an epigenetic mark that is associated with transcriptional repression of transposable elements and protein-coding genes. Conversely, transcriptionally active regulatory regions are strongly correlated with histone 3 lysine 4 di- an
Externí odkaz:
https://doaj.org/article/4d5c85778e834783b354d7649c78bc64
Autor:
Elena Caro, Hume Stroud, Maxim V C Greenberg, Yana V Bernatavichute, Suhua Feng, Martin Groth, Ajay A Vashisht, James Wohlschlegel, Steve E Jacobsen
Publikováno v:
PLoS Genetics, Vol 8, Iss 10, p e1002995 (2012)
In eukaryotic cells, environmental and developmental signals alter chromatin structure and modulate gene expression. Heterochromatin constitutes the transcriptionally inactive state of the genome and in plants and mammals is generally characterized b
Externí odkaz:
https://doaj.org/article/1b85423849a44009ad4dadb09ad99772