Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Maxim V, Skulachev"'
Autor:
Pavel A. Nazarov, Vladislav S. Maximov, Alexander M. Firsov, Marina V. Karakozova, Veronika Panfilova, Elena A. Kotova, Maxim V. Skulachev, Yuri N. Antonenko
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6137 (2024)
Mitochondria-targeted antioxidants (MTAs) have been studied quite intensively in recent years as potential therapeutic agents and vectors for the delivery of other active substances to mitochondria and bacteria. Their most studied representatives are
Externí odkaz:
https://doaj.org/article/60d327de2eb64c31baf99c99657766e1
Autor:
Vladimir P. Skulachev, Mikhail Yu. Vyssokikh, Boris V. Chernyak, Armen Y. Mulkidjanian, Maxim V. Skulachev, Gregory A. Shilovsky, Konstantin G. Lyamzaev, Vitaliy B. Borisov, Fedor F. Severin, Victor A. Sadovnichii
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12540 (2023)
Cellular respiration is associated with at least six distinct but intertwined biological functions. (1) biosynthesis of ATP from ADP and inorganic phosphate, (2) consumption of respiratory substrates, (3) support of membrane transport, (4) conversion
Externí odkaz:
https://doaj.org/article/e0c1fa324f424ca8a9e70842da931f30
Publikováno v:
Pharmaceuticals, Vol 16, Iss 5, p 688 (2023)
The penetration of substances through the bacterial cell envelope is a complex and underinvestigated process. Mitochondria-targeted antioxidant and antibiotic SkQ1 (10-(plastoquinonyl)decyltriphenylphosphonium) is an excellent model for studying the
Externí odkaz:
https://doaj.org/article/64c67f6bb0054bfaaf24e056c36b62c6
Autor:
Mikhail V. Samsonov, Nikita V. Podkuychenko, Asker Y. Khapchaev, Eugene E. Efremov, Elena V. Yanushevskaya, Tatiana N. Vlasik, Vadim Z. Lankin, Iurii S. Stafeev, Maxim V. Skulachev, Marina V. Shestakova, Alexander V. Vorotnikov, Vladimir P. Shirinsky
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 211 (2021)
Hyperlipidemia manifested by high blood levels of free fatty acids (FFA) and lipoprotein triglycerides is critical for the progression of type 2 diabetes (T2D) and its cardiovascular complications via vascular endothelial dysfunction. However, attemp
Externí odkaz:
https://doaj.org/article/a7d61f60f00141f084647cebcdcb2eb7
Autor:
Pavel A. Nazarov, Ilya A. Osterman, Artem V. Tokarchuk, Marina V. Karakozova, Galina A. Korshunova, Konstantin G. Lyamzaev, Maxim V. Skulachev, Elena A. Kotova, Vladimir P. Skulachev, Yuri N. Antonenko
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Mitochondria-targeted antioxidants are known to alleviate mitochondrial oxidative damage that is associated with a variety of diseases. Here, we showed that SkQ1, a decyltriphenyl phosphonium cation conjugated to a quinone moiety, exhibited
Externí odkaz:
https://doaj.org/article/15da0121ba4a44c098f410443074d542
Autor:
T S Putyatina, Vladimir P. Skulachev, Maxim V. Skulachev, G. A. Shilovsky, Nikita A Popov, Victor Antonovich Sadovnichii, Alexander V. Markov
Publikováno v:
Aging. 12:5566-5584
Homo sapiens and naked mole rats (Heterocephalus glaber) are vivid examples of social mammals that differ from their relatives in particular by an increased lifespan and a large number of neotenic features. An important fact for biogerontology is tha
Autor:
Alisa A. Panteleeva, Thomas B. Hildebrandt, O. A. Averina, Vladimir P. Skulachev, Mikhail Yu. Vyssokikh, Roman A. Zinovkin, Nicolas Fasel, Fedor F. Severin, Konstantin G. Lyamzaev, M. V. Marey, Susanne Holtze, Maxim V. Skulachev
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 117(12):6491-6501
Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 12, pp. 6491-6501
Proceedings of the National Academy of Sciences of the United States of America, 117(12):6491-6501
Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 12, pp. 6491-6501
Significance The mitochondria, organelles that produce the largest amounts of ATP and reactive oxygen species (mROS) in living cells, are equipped with a universal mechanism that can completely prevent mROS production. This mechanism consists of mild
Autor:
Alexei Solovchenko, Pavel Scherbakov, Olga Gorelova, Rima I. Samoilova, L. R. Semenova, S. G. Vasilieva, A. A. Lukyanov, Andrey V. Golovin, Andrew Y. Bychkov, Maxim V. Skulachev, I.O. Selyakh, Olga Baulina, Mikhail P. Kirpichnikov, Olga B. Chivkunova, Leonid V. Kulik, Elena Lobakova, Tatiana Ismagulova, Vasily V. Ptushenko
Publikováno v:
Photosynthesis Research. 142:229-240
Mitochondria-targeted antioxidants (also known as 'Skulachev Ions' electrophoretically accumulated by mitochondria) exert anti-ageing and ROS-protecting effects well documented in animal and human cells. However, their effects on chloroplast in photo
Autor:
Andrew Troger, Anton Petrov, Natalia Perekhvatova, Viola Spahiu, Maxim V. Skulachev, Penny A. Asbell, Yi Wei, Boris V. Chernyak
Publikováno v:
Ophthalmology and Therapy, Vol 8, Iss 1, Pp 63-73 (2018)
Ophthalmology and Therapy
Ophthalmology and Therapy
Introduction SkQ1 (Visomitin) is a novel mitochondrial-targeted antioxidant that holds promise in the treatment of inflammation associated with ocular surface diseases such as dry eye disease (DED) and corneal wounds. However, the specific role of Sk
Autor:
Vladimir P, Skulachev, Gregory A, Shilovsky, Tatyana S, Putyatina, Nikita A, Popov, Alexander V, Markov, Maxim V, Skulachev, Victor A, Sadovnichii
Publikováno v:
Aging (Albany NY)
Homo sapiens and naked mole rats (Heterocephalus glaber) are vivid examples of social mammals that differ from their relatives in particular by an increased lifespan and a large number of neotenic features. An important fact for biogerontology is tha