Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Maxim I. Lutskiy"'
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3444 (2008)
Population level evolutionary processes can occur within a single organism when the germ line contains a mutation that confers a cost at the level of the cell. Here we describe how multiple compensatory mutations arose through a within-individual evo
Externí odkaz:
https://doaj.org/article/b16e598cf7d441f989dfd1f017262af1
Autor:
Janet Chou, Luigi D. Notarangelo, Maxim I. Lutskiy, Erdyni N. Tsitsikov, Anahita F. Dioun, Raif S. Geha
Publikováno v:
Journal of Allergy and Clinical Immunology. 134:223-226
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84012397675f4a856611d46b8cc5c660
https://doi.org/10.1016/j.jaci.2014.01.041
https://doi.org/10.1016/j.jaci.2014.01.041
Publikováno v:
Blood. 100:2763-2768
Wiskott-Aldrich syndrome (WAS) is an X-linked disease characterized by thrombocytopenia, eczema, and various degrees of immune deficiency. Carriers of mutated WASP have nonrandom X chromosome inactivation in their blood cells and are disease-free. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7c194fd5513685a19485d3a1e434698
https://doi.org/10.1182/blood-2002-02-0388
https://doi.org/10.1182/blood-2002-02-0388
Autor:
Eileen Remold-O'Donnell, Fred S. Rosen, Dianne M. Kenney, Jessica Cooley, L.N. Jones, Maxim I. Lutskiy
Publikováno v:
Blood Cells, Molecules, and Diseases. 28:392-398
Mutations of WASP (Wiskott-Aldrich syndrome protein) underlie the severe immunodeficiency/platelet disorder Wiskott-Aldrich syndrome (WAS) and its milder variant X-linked thrombocytopenia (XLT). The affected gene, a 12-exon structure on the X-chromos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdf3824d8fc8f8ee5662d80b5349da09
https://doi.org/10.1006/bcmd.2002.0523
https://doi.org/10.1006/bcmd.2002.0523
Publikováno v:
Human Genetics. 110:515-519
Wiskott-Aldrich syndrome (WAS) is an X-linked disease characterized by thrombocytopenia, eczema and immunodeficiency of varying severity. The WASP gene, mutations of which are responsible for the phenotype, maps to Xp11.23. We describe here a patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::937210aa90b031b851a4160044059893
https://doi.org/10.1007/s00439-002-0716-4
https://doi.org/10.1007/s00439-002-0716-4
Autor:
Anna Shcherbina, Eileen Remold-O'Donnell, Gary E. Gilbert, Jessica Cooley, Maxim I. Lutskiy, Charaf Benarafa
Publikováno v:
British journal of haematology. 148(3)
The most consistent feature of Wiskott Aldrich syndrome (WAS) is profound thrombocytopenia with small platelets. The responsible gene encodes WAS protein (WASP), which functions in leucocytes as an actin filament nucleating agent -yet- actin filament
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db0ad7ff6fc11bb2627c3064f39a86d
https://pubmed.ncbi.nlm.nih.gov/19863535
https://pubmed.ncbi.nlm.nih.gov/19863535
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 175(2)
Wiskott-Aldrich syndrome (WAS) is a platelet/immunodeficiency disease arising from mutations of WAS protein (WASP), a hemopoietic cytoskeletal protein. Clinical symptoms vary widely from mild (X-linked thrombocytopenia) to life threatening. In this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea673ef56410b209b30a03488a13aa10
https://pubmed.ncbi.nlm.nih.gov/16002738
https://pubmed.ncbi.nlm.nih.gov/16002738
Publikováno v:
Blood. 106(8)
Rare cases of somatic mosaicism resulting from reversion of inherited mutations can lead to the attenuation of blood-cell disorders, including Wiskott-Aldrich syndrome (WAS). The impact of the revertant hematopoietic stem or progenitor cells, particu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2f2694d27bd8f96f235315fd71bd743
https://pubmed.ncbi.nlm.nih.gov/15985539
https://pubmed.ncbi.nlm.nih.gov/15985539
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3444 (2008)
PLoS ONE
PLoS ONE
Population level evolutionary processes can occur within a single organism when the germ line contains a mutation that confers a cost at the level of the cell. Here we describe how multiple compensatory mutations arose through a within-individual evo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69c73c89d861edcbbba4ad25fe453310
https://doi.org/10.1371/journal.pone.0003444
https://doi.org/10.1371/journal.pone.0003444