Výsledky vyhledávání - "Maxim G. Brevnov"

Analytical Validation of a Single-nucleotide Polymorphism-based Donor-derived Cell-free DNA Assay for Detecting Rejection in Kidney Transplant Patients

Autor: Bernhard Zimmermann, Rosalyn Ram, Harini Ravi, Ryan Swenerton, Meenakshi Malhotra, Yucel Altug, Allison M. Ryan, Maxim G. Brevnov, Zachary Demko, Paul Billings, Ebad Ahmed, Nathan Liang

Publikováno v: Transplantation

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Background. Early detection of rejection in kidney transplant recipients holds the promise to improve clinical outcomes. Development and implementation of more accurate, noninvasive methods

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::284fa82e7b893b292b6f8a51e526f685
https://doi.org/10.1097/tp.0000000000002665

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Abstract 569: Correlation of variant allele frequency and mean tumor molecules with tumor burden in patients with solid tumors

Autor: Angel Rodriguez, Vasily N. Aushev, Raheleh Salari, Gordon Fehringer, Ekaterina Kalashnikova, Maxim G. Brevnov, Himanshu Sethi, Svetalana Shchegrova, Meenakshi Malhotra, Alexey Aleshin, Bernhard Zimmermann, Paul Billings, Harini Ravi, Antony Tin

Publikováno v: Cancer Research. 81:569-569

Introduction: Two metrics are commonly used to quantify tumor-specific variants in cell-free DNA (cfDNA): the variant allele frequency (VAF), defined as the ratio of the number of variant alleles to wild-type alleles, and mean tumor molecules (MTM)/m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::323fd6ca051646c9f0e558ed9c130622
https://doi.org/10.1158/1538-7445.am2021-569

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AutoMate Express™ Forensic DNA Extraction System for the Extraction of Genomic DNA from Biological Samples*

Autor: Michael Harrold, Jaiprakash G. Shewale, Maxim G. Brevnov, Jason Yingjie Liu, Allison Holt, Chang Zhong, Lori K. Hennessy, Robert Lagacé, Alan B. Dixon

Publikováno v: Journal of Forensic Sciences. 57:1022-1030

The AutoMate Express™ Forensic DNA Extraction System was developed for automatic isolation of DNA from a variety of forensic biological samples. The performance of the system was investigated using a wide range of biological samples. Depending on t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::af2f9aa35a60bd5ba7f6dce48705a49c
https://doi.org/10.1111/j.1556-4029.2012.02084.x

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A Sample Extraction Method for Faster, More Sensitive PCR-Based Detection of Pathogens in Blood Culture

Autor: Manohar R. Furtado, Maxim G. Brevnov, Jeanne A. Jordan, John F. Regan

Publikováno v: The Journal of Molecular Diagnostics. 14:120-129

Three mechanistically different sample extraction methodologies, namely, silica spin columns, phenol-chloroform, and an automated magnetic capture of polymer-complexed DNA (via an Automate Express instrument), were compared for their abilities to pur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f1cb1e07f8206d8a57c0305f01ca26f
https://doi.org/10.1016/j.jmoldx.2011.10.001

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Automated Extraction of DNA from Forensic Sample Types Using the PrepFiler Automated Forensic DNA Extraction Kit

Autor: Jason Meredith, Manohar R. Furtado, Jaiprakash G. Shewale, Lynda Treat-Clemons, Maxim G. Brevnov, Geert Kalusche, Janna M. Mundt, Gregory Porter, Jacki Benfield

Publikováno v: JALA: Journal of the Association for Laboratory Automation. 14:294-302

The HID EVOlution—Extraction System (Tecan Group Ltd., Mannedorf, Switzerland) was developed to automate DNA extraction from biological samples using the PrepFiler Automated Forensic DNA Extraction Kit (Applied Biosystems, Foster City, CA). The sys

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bf6865601ce53f9f77681ee3bd9a7d4c
https://doi.org/10.1016/j.jala.2009.06.006

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Probing of contacts between EcoRII DNA methyltransferase and DNA with the use of substrate analogs and molecular modeling

Autor: Maxim G. Brevnov, O. A. Rechkoblit, Oksana M. Subach, Janusz M. Bujnicki, Elizaveta V. Koudan, Elizaveta S. Gromova

Publikováno v: Molecular Biology. 41:806-819

The molecular mechanisms of DNA recognition and modification by EcoRII DNA methyltransferase (M.EcoRII) were studied using 14-mer substrate analogs containing 2-aminopurine or 1′,2′-dideoxy-D-ribofuranose in the M.EcoRII recognition site. The eff

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6ae94571433eb415dc5b2dba80e0a782
https://doi.org/10.1134/s0026893307050147

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Parallel Self-Associated Structures Formed by T,C-Rich Sequences at Acidic pH

Autor: Jean Liquier, Maxim G. Brevnov, Frédéric Geinguenaud, Elizaveta S. Gromova, Yakov I. Alexeev, Eliane Taillandier, Olga Petrauskene

Publikováno v: Biochemistry. 39:12650-12658

Oligonucleotides of nonregular heteropyrimidine sequences incorporating or not incorporating purine residues 5'-d(ACTCCCTTCTCCTCTCTA), 5'-d(ACTCCCTGGTCCTCTCTA), 5'-d(TCTCTCCTGGTCCCTCC), and 5'-d(TCTCTCCTCTTCCCTCC) can form self-associated parallel-st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c18a4d3e363934ead82c7ca32aa3a0a6
https://doi.org/10.1021/bi000746+

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TheEcl18kI restriction-modification system: cloning, expression, properties of the purified enzymes

Autor: Olga Petrauskene, Gromova Es, Maxim G. Brevnov, M. V. Zakharova, Alexander S. Solonin, M.M. Denjmukhametov, Alexander V. Repyk

Publikováno v: FEBS Letters. 433:233-236

Ecl18kI is a type II restriction-modification system isolated from Enterobacter cloaceae 18kI strain. Genes encoding Ecl18kI methyltransferase (M.Ecl18kI) and Ecl18kI restriction endonuclease (R.Ecl18kI) have been cloned and expressed in Escherichia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e17dc7081c4c7e7cfa0a7eb8ee1d3595
https://doi.org/10.1016/s0014-5793(98)00921-1

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Synthesis of a new Photo-Cross-Linking Nucleoside Analogue Containing an Aryl(Trifluoromethyl)Diazirine Group: Application forEcoRII andMvaI Restriction-Modification Enzymes

Autor: Galina A. Korshunova, Maxim G. Brevnov, O. M. Gritsenko, A. N. Topin, Elisaveta S. Gromova

Publikováno v: Nucleosides and Nucleotides. 17:1163-1175

A new photo-cross-linking dU analog, 5-[4-(3-(trifluoromethyl)-3H-diazirin-3-yl)phenyl]-2′-deoxyuridine, was synthesized and incorporated into the recognition site of Eco RII and Mva I restriction-modification enzymes. The resulting base-modified 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e864af05ec2455bdd4b8fd1b9a59e104
https://doi.org/10.1080/07328319808004229

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Real-time PCR assays for the detection of tissue and body fluid specific mRNAs

Autor: Maxim G. Brevnov, C.F. Manohar, Christine N. Shulse, Ada H. Wong, Olga Petrauskene, Pius Brzoska, Rixun Fang, Manohar R. Furtado

Publikováno v: International Congress Series. 1288:685-687

Identification of tissue parts and body fluids is frequently required in crime scene investigations. We analysed expression data from public databases and internal studies to identify 110 highly expressed mRNAs as potential tissue specific markers. F

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https://doi.org/10.1016/j.ics.2005.10.064

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