Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Maxim D. Lootsik"'
Autor:
Christina Janko, Maxim D. Lootsik, Tetyana Dumych, Christoph Alexiou, Andriy Mokhir, Leopold Sellner, Rostyslav Bilyy, Miroslav Sisa, Martin Herrmann, Evgenia Bila, Steffen Daum, M. S. Viktor Reshetnikov
Publikováno v:
Angewandte Chemie. 129:15751-15755
Cancer cells produce elevated levels of reactive oxygen species, which has been used to design cancer specific prodrugs. Their activation relies on at least a bimolecular process, in which a prodrug reacts with ROS. However, at low micromolar concent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe9d1e344a256830a27b66482007a07
https://doi.org/10.1002/ange.201706585
https://doi.org/10.1002/ange.201706585
Autor:
Ricardo A. Chaurio, Maxim D. Lootsik, Malgorzata J. Podolska, Christoph Alexiou, Christian Berens, Christian Maueröder, Ralf P Friedrich, Luis E. Muñoz, Rostyslav Bilyy, Georg Schett, Martin Herrmann, Tetiana Dumych, Stephan Culemann
Publikováno v:
Cell Death & Differentiation. 23:1016-1025
In this study, we deploy a doxycycline-dependent suicide switch integrated in a tumor challenge model. With this experimental setup, we characterized the immunological consequences of cells dying by four distinct cell death stimuli in vivo. We observ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e71cb070d3ed3ee5f81332cc4bf600de
https://doi.org/10.1038/cdd.2016.4
https://doi.org/10.1038/cdd.2016.4
Publikováno v:
Open Journal of Blood Diseases. :1-6
Scheme of detection and investigation of antitumor activity of chemical substances by use of experimental murine Nemeth-Kellner lymphoma (NK/Ly) are described. It includes monitoring of growth of NK/Ly ascites by everyday weighting of animals in cour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d9934a7b76ce46b9cb6a0648677f01d
https://doi.org/10.4236/ojbd.2013.33a001
https://doi.org/10.4236/ojbd.2013.33a001
Autor:
Mona H C Biermann, Daniela Weidner, Marina Scharin-Mehlmann, Luis E. Muñoz, Christine Schauer, Ralf P Friedrich, Martin Herrmann, Yi Zhao, Georg Schett, Jonas Hahn, Tetiana Dumych, Deborah Kienhöfer, Jin Chen, Rostyslav Bilyy, Christina Janko, Markus H. Hoffmann, Christian Maueröder, Dirk Mielenz, Maxim D. Lootsik, Jan Markus Brauner
Publikováno v:
Proceedings of the National Academy of Sciences
The critical size for strong interaction of hydrophobic particles with phospholipid bilayers has been predicted to be 10 nm. Because of the wide spreading of nonpolar nanoparticles (NPs) in the environment, we aimed to reveal the ability of living or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b274578e610ef817dcffce2666ae8e2a
https://europepmc.org/articles/PMC5056044/
https://europepmc.org/articles/PMC5056044/
Publikováno v:
Open Life Sciences, Vol 2, Iss 1, Pp 71-86 (2007)
The main goal of this study was to evaluate if specific cytokine expression in the NK/Ly lymphoma cells might be involved in development of intoxication in the tumor-bearing animals. RT-PCR analysis was used to study an expression of mRNA coding for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a772828befcbc85e6178f499b1fb2f78
https://doaj.org/article/9a8f8ff6460b40f69814d108b03a4602
https://doaj.org/article/9a8f8ff6460b40f69814d108b03a4602
Publikováno v:
Open Life Sciences, Vol 1, Iss 1, Pp 2-15 (2006)
The purpose of this study was to examine the relationship between the DNA intercalating characteristics and the DNA damaging capacity of four alkaloids extracted from Chelidonium majus L, as well as their toxicity towards murine NK/Ly lymphoma cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb4c1e2b648335a8b8a9b07e5317310a
https://doaj.org/article/fab18674621941288aa10746f54060b4
https://doaj.org/article/fab18674621941288aa10746f54060b4
Publikováno v:
Cell biology international. 36(1)
Respiration characteristics of mitochondria of the parental and giant cells of murine NK/Ly (Nemeth-Kellner lymphoma) were studied. The giant cell-enriched ascites were obtained by serial intraperitoneal injections of vinblastine in tumour-bearing mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c3e357c3cc31574b57f497fbf57d145
https://pubmed.ncbi.nlm.nih.gov/21899518
https://pubmed.ncbi.nlm.nih.gov/21899518
Publikováno v:
Cell biology international. 32(9)
Expression of specific proteins involved in regulation of cell proliferation and apoptosis was studied at the initial (7–8 days after tumor inoculation), median (13–14 days), and terminal (20–21 days) stages of murine NK/Ly lymphoma development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7919d47bf01d417d255944bcc22b775
https://pubmed.ncbi.nlm.nih.gov/18598774
https://pubmed.ncbi.nlm.nih.gov/18598774