Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Maxim Burgman"'
Autor:
Gavril W. Pasternak, Valerie Le Rouzic, Lisa Polikar, Ying-Xian Pan, Michael Ansonoff, John E. Pintar, Susruta Majumdar, Maxim Burgman, Steven G. Grinnell
Publikováno v:
Proceedings of the National Academy of Sciences. 108:19778-19783
Pain remains a pervasive problem throughout medicine, transcending all specialty boundaries. Despite the extraordinary insights into pain and its mechanisms over the past few decades, few advances have been made with analgesics. Most pain remains tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40c11d85477767e8d5ca78837a863670
https://doi.org/10.1073/pnas.1115231108
https://doi.org/10.1073/pnas.1115231108
Autor:
Nathan Haselton, Anna R. Pasternak, Susruta Majumdar, Gavril W. Pasternak, Julia Ocampo, Steven G. Grinnell, Maxim Burgman
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:4001-4004
Tritiated opioid radioligands have proven valuable in exploring opioid binding sites. However, tritium has many limitations. Its low specific activity and limited counting efficiency makes it difficult to examine low abundant, high affinity sites and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8965f7a8c53c56745bccfa4a93472818
https://doi.org/10.1016/j.bmcl.2011.05.008
https://doi.org/10.1016/j.bmcl.2011.05.008
Autor:
Susruta Majumdar, Gavril W. Pasternak, Nathan Haselton, Ying-Xian Pan, Julie Ocampo, Anna R. Pasternak, Steven G. Grinnell, Kuni Nagakura, Lisa Polikar, Maxim Burgman, Valerie Le Rouzic, Joan J. Subrath
3-Iodobenzoylnaltrexamide 1 (IBNtxA) is a potent analgesic acting through a novel receptor target that lack many side-effects of traditional opiates composed, in part, of exon 11-associated truncated six transmembrane domain MOR-1 (6TM/E11) splice va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c88f0f108e54f15be05eb51405ae7ed3
https://europepmc.org/articles/PMC3412067/
https://europepmc.org/articles/PMC3412067/
Publikováno v:
The FASEB Journal. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::167087e57af7444aef7fe7a3aedc9003
https://doi.org/10.1096/fasebj.24.1_supplement.581.1
https://doi.org/10.1096/fasebj.24.1_supplement.581.1
Autor:
Maxim Burgman, Felix J. Kim, Ivanka Kovalyshyn, Claire L. Neilan, Gavril W. Pasternak, Chih-Cheng Chien
Publikováno v:
Molecular pharmacology. 77(4)
sigma Ligands modulate opioid actions in vivo, with agonists diminishing morphine analgesia and antagonists enhancing the response. Using human BE(2)-C neuroblastoma cells that natively express opioid receptors and human embryonic kidney (HEK) cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06156063e7766cb3ad33c1d7b6b8cc1a
https://pubmed.ncbi.nlm.nih.gov/20089882
https://pubmed.ncbi.nlm.nih.gov/20089882