Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Maxim A, Gureev"'
Autor:
Olga I. Yarovaya, Aleksandr S. Filimonov, Dmitriy S. Baev, Sophia S. Borisevich, Anna V. Zaykovskaya, Varvara Yu. Chirkova, Mariya K. Marenina, Yulia V. Meshkova, Svetlana V. Belenkaya, Dmitriy N. Shcherbakov, Maxim A. Gureev, Olga A. Luzina, Oleg V. Pyankov, Nariman F. Salakhutdinov, Mikhail V. Khvostov
Publikováno v:
Viruses, Vol 16, Iss 2, p 215 (2024)
Although the COVID-19 pandemic caused by SARS-CoV-2 viruses is officially over, the search for new effective agents with activity against a wide range of coronaviruses is still an important task for medical chemists and virologists. We synthesized a
Externí odkaz:
https://doaj.org/article/f8027d82e2904b38a99ec1ab28d8aae6
Autor:
Andrey V. Khramchikhin, Mariya A. Skryl’nikova, Maxim A. Gureev, Vladimir V. Zarubaev, Iana L. Esaulkova, Polina A. Ilyina, Oussama Abdelhamid Mammeri, Dar’ya V. Spiridonova, Yuri B. Porozov, Vladimir A. Ostrovskii
Publikováno v:
Molecules, Vol 28, Iss 21, p 7427 (2023)
A novel method for synthesizing 1,2,4-triazole- and tetrazole-containing 4H-thiopyrano[2,3-b]quinolines using a new combination of the thio-Michael and aza-Morita–Baylis–Hillman reactions was developed. Target compounds were evaluated for their c
Externí odkaz:
https://doaj.org/article/9eaf67032beb471589bde340bd8a037b
Autor:
Olga Babich, Viktoria Larina, Olesia Krol, Elena Ulrikh, Stanislav Sukhikh, Maxim A. Gureev, Alexander Prosekov, Svetlana Ivanova
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 616 (2023)
Tanacetum vulgare is an herbaceous plant widely used in folk medicine. It is rich in phenolic acids and flavonoids, which have pharmacological and medicinal properties, such as anthelmintic, antispasmodic, tonic, antidiabetic, diuretic, and antihyper
Externí odkaz:
https://doaj.org/article/24da19700baf48a697ae44665f925d13
Autor:
Andrey V. Khramchikhin, Mariya A. Skryl’nikova, Iana L. Esaulkova, Ekaterina O. Sinegubova, Vladimir V. Zarubaev, Maxim A. Gureev, Aleksandra M. Puzyk, Vladimir A. Ostrovskii
Publikováno v:
Molecules, Vol 27, Iss 22, p 7940 (2022)
This study of the interaction system of binucleophilic 3-substituted 4-amino-4H-1,2,4-triazole-5-thiols and 3-phenyl-2-propynal made it possible to develop a new approach to synthesis of such isomeric classes as 7-benzylidene-[1,2,4]triazolo[3,4-b][1
Externí odkaz:
https://doaj.org/article/a8c1e5f826574dec9a1c2d9641285a24
Autor:
Natalia A. Danilkina, Ekaterina A. Khmelevskaya, Anna G. Lyapunova, Alexander S. D’yachenko, Alexander S. Bunev, Rovshan E. Gasanov, Maxim A. Gureev, Irina A. Balova
Publikováno v:
Molecules, Vol 27, Iss 18, p 6071 (2022)
The scope and limitations of the Nicholas-type cyclization for the synthesis of 10-membered benzothiophene-fused heterocyclic enediynes with different functionalities were investigated. Although the Nicholas cyclization through oxygen could be carrie
Externí odkaz:
https://doaj.org/article/418e404c8d404aa5abefedcc37995ca3
Autor:
Olga I. Yarovaya, Dmitriy N. Shcherbakov, Sophia S. Borisevich, Anastasiya S. Sokolova, Maxim A. Gureev, Edward M. Khamitov, Nadezda B. Rudometova, Anastasiya V. Zybkina, Ekaterina D. Mordvinova, Anna V. Zaykovskaya, Artem D. Rogachev, Oleg V. Pyankov, Rinat A. Maksyutov, Nariman F. Salakhutdinov
Publikováno v:
Viruses, Vol 14, Iss 6, p 1295 (2022)
In the present work we studied the antiviral activity of the home library of monoterpenoid derivatives using the pseudoviral systems of our development, which have glycoproteins of the SARS-CoV-2 virus strains Wuhan and Delta on their surface. We fou
Externí odkaz:
https://doaj.org/article/0801fba33b9444c79b2014fcc3bb8a46
Autor:
Ivan O. Maslov, Tatiana V. Zinevich, Olga G. Kirichenko, Mikhail V. Trukhan, Sergey V. Shorshnev, Natalya O. Tuaeva, Maxim A. Gureev, Amelia D. Dahlén, Yuri B. Porozov, Helgi B. Schiöth, Vladimir M. Trukhan
Publikováno v:
Pharmaceuticals, Vol 15, Iss 3, p 273 (2022)
Compounds that contain (R)-3-amino-4-(2,4,5-trifluorophenyl)butanoic acid substituted with bicyclic amino moiety (2-aza-bicyclo[2.2.1]heptane) were designed using molecular modelling methods, synthesised, and found to be potent DPP-4 (dipeptidyl pept
Externí odkaz:
https://doaj.org/article/eb8f6f6ae0d9464ea7a070f9095c60ed
Autor:
Sophia S. Borisevich, Edward M. Khamitov, Maxim A. Gureev, Olga I. Yarovaya, Nadezhda B. Rudometova, Anastasiya V. Zybkina, Ekaterina D. Mordvinova, Dmitriy N. Shcherbakov, Rinat A. Maksyutov, Nariman F. Salakhutdinov
Publikováno v:
Viruses, Vol 14, Iss 1, p 119 (2022)
In this work, we evaluated the antiviral activity of Arbidol (Umifenovir) against SARS-CoV-2 using a pseudoviral system with the glycoprotein S of the SARS-CoV-2 virus on its surface. In order to search for binding sites to protein S of the virus, we
Externí odkaz:
https://doaj.org/article/96324727f17f40e2b9a078db23748bfe
Autor:
Denis A. Borozdenko, Aiarpi A. Ezdoglian, Tatiana A. Shmigol, Darya I. Gonchar, Dmitri N. Lyakhmun, Dmitri V. Tarasenko, Yaroslav V. Golubev, Elvira A. Cherkashova, Daria D. Namestnikova, Ilya L. Gubskiy, Alexey A. Lagunin, Leonid V. Gubsky, Vladimir P. Chekhonin, Sophia S. Borisevich, Maxim A. Gureev, Anastasia D. Shagina, Nina M. Kiseleva, Vadim V. Negrebetsky, Yuri I. Baukov
Publikováno v:
Molecules, Vol 26, Iss 20, p 6124 (2021)
We performed an in silico, in vitro, and in vivo assessment of a potassium 2-[2-(2-oxo-4-phenylpyrrolidin-1-yl) acetamido]ethanesulfonate (compound 1) as a potential prodrug for cognitive function improvement in ischemic brain injury. Using in silico
Externí odkaz:
https://doaj.org/article/2b3a5471b2ee494e851c618e38e99ac8
Autor:
Sergey V. Baykov, Alexander S. Mikherdov, Alexander S. Novikov, Kirill K. Geyl, Marina V. Tarasenko, Maxim A. Gureev, Vadim P. Boyarskiy
Publikováno v:
Molecules, Vol 26, Iss 18, p 5672 (2021)
A series of N-pyridyl ureas bearing 1,2,4- (1a, 2a, and 3a) and 1,3,4-oxadiazole moiety (1b, 2b, 3b) was prepared and characterized by HRMS, 1H and 13C NMR spectroscopy, as well as X-ray diffraction. The inspection of the crystal structures of (1–3
Externí odkaz:
https://doaj.org/article/6c27243a3fb84fa9afb152b76eb94c68