Zobrazeno 1 - 10
of 169
pro vyhledávání: '"MaxiK channel"'
Publikováno v:
Advances in Drug and Alcohol Research, Vol 3 (2023)
Despite the significant number of people who may be taking pregnenolone supplements while drinking alcohol (ethanol), the widely documented cerebrovascular actions of pregnenolone and ethanol, and the critical dependence of cerebrovascular function o
Externí odkaz:
https://doaj.org/article/8d09a388bacd4d38acebd4ee393c978c
Autor:
Sara V. Ochoa, Liliana Otero, Andres Felipe Aristizabal-Pachon, Fernando Hinostroza, Ingrid Carvacho, Yolima P. Torres
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Hypoxia is a condition characterized by a reduction of cellular oxygen levels derived from alterations in oxygen balance. Hypoxic events trigger changes in cell-signaling cascades, oxidative stress, activation of pro-inflammatory molecules, and growt
Externí odkaz:
https://doaj.org/article/c019d4831950428b95a21f9f55bdc288
Autor:
Xiao Tao, Roderick MacKinnon
Publikováno v:
eLife, Vol 8 (2019)
Slo1 is a Ca2+- and voltage-activated K+ channel that underlies skeletal and smooth muscle contraction, audition, hormone secretion and neurotransmitter release. In mammals, Slo1 is regulated by auxiliary proteins that confer tissue-specific gating a
Externí odkaz:
https://doaj.org/article/4ad26397faf64b9ba00cd134e10ad719
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 10; Pages: 8704
Calcium/voltage-activated potassium channels (BK) control smooth muscle (SM) tone and cerebral artery diameter. They include channel-forming α and regulatory β1 subunits, the latter being highly expressed in SM. Both subunits participate in steroid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::096ebb61bd8e5e06c38c278d64092530
Akademický článek
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Publikováno v:
Journal of Lipid Research, Vol 49, Iss 11, Pp 2441-2451 (2008)
Lithocholate (LC) (10–300 μM) in physiological solution is sensed by vascular myocyte large conductance, calcium- and voltage-gated potassium (BK) channel β1 accessory subunits, leading to channel activation and arterial dilation. However, the st
Externí odkaz:
https://doaj.org/article/d6060b2e96eb4e1383c4056384a37db7
Publikováno v:
Frontiers in Physiology, Vol 6 (2015)
Since its discovery in a glioma cell line 15 years ago, mitochondrial BKCa channel (mitoBKCa) has been studied in brain cells and cardiomyocytes sharing general biophysical properties such as high K+ conductance (~300 pS), voltage-dependency and Ca2+
Externí odkaz:
https://doaj.org/article/1602746dc1e542958565e31b4886a36f
Akademický článek
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Autor:
Michael J Shipston
Publikováno v:
Frontiers in Physiology, Vol 5 (2014)
Mechanisms that control surface expression and/or activity of large conductance calcium-activated potassium (BK) channels are important determinants of their (patho)physiological function. Indeed, BK channel dysfunction is associated with major human
Externí odkaz:
https://doaj.org/article/4b449090684e4a8585a8cc3bc657d3cc
Autor:
Alex M. Dopico, Anna N. Bukiya
Publikováno v:
Frontiers in Physiology, Vol 5 (2014)
This mini-review focuses on lipid modulation of BK (MaxiK, BKCa) current by a direct interaction between lipid and the BK subunits and/or their immediate lipid environment. Direct lipid-BK protein interactions have been proposed for fatty and epoxyei
Externí odkaz:
https://doaj.org/article/a678ae690f0b40eeb12561afb44958a8