Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Maxence O. Dellacherie"'
Autor:
Kwasi Adu-Berchie, Joshua M. Brockman, Yutong Liu, Tania W. To, David K. Y. Zhang, Alexander J. Najibi, Yoav Binenbaum, Alexander Stafford, Nikolaos Dimitrakakis, Miguel C. Sobral, Maxence O. Dellacherie, David J. Mooney
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Although adoptive T cell therapy provides the T cell pool needed for immediate tumor debulking, the infused T cells generally have a narrow repertoire for antigen recognition and limited ability for long-term protection. Here, we present a h
Externí odkaz:
https://doaj.org/article/c82858dc6c3249e0bed06dcad9fd4919
Autor:
Soumya Badrinath, Maxence O. Dellacherie, Aileen Li, Shiwei Zheng, Xixi Zhang, Miguel Sobral, Jason W. Pyrdol, Kathryn L. Smith, Yuheng Lu, Sabrina Haag, Hamza Ijaz, Fawn Connor-Stroud, Tsuneyasu Kaisho, Glenn Dranoff, Guo-Cheng Yuan, David J. Mooney, Kai W. Wucherpfennig
Publikováno v:
Nature. 606:992-998
Most cancer vaccines target peptide antigens, necessitating personalization owing to the vast inter-individual diversity in major histocompatibility complex (MHC) molecules that present peptides to T cells. Furthermore, tumours frequently escape T ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::967fb420c630f072c3768d5bd986d27f
https://doi.org/10.1038/s41586-022-04772-4
https://doi.org/10.1038/s41586-022-04772-4
Autor:
Alexander J. Najibi, Ting-Yu Shih, David K. Y. Zhang, Junzhe Lou, Miguel C. Sobral, Hua Wang, Maxence O. Dellacherie, Kwasi Adu-Berchie, David J. Mooney
Publikováno v:
Cancer Immunology, Immunotherapy. 71:2957-2968
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67e63264ea35079f1187ea8eba41feaa
https://doi.org/10.1007/s00262-022-03212-6
https://doi.org/10.1007/s00262-022-03212-6
Autor:
Alexander J. Najibi, Ryan S. Lane, Miguel C. Sobral, Benjamin R. Freedman, Joel Gutierrez Estupinan, Alberto Elosegui-Artola, Christina M. Tringides, Maxence O. Dellacherie, Katherine Williams, Sören Müller, Shannon J. Turley, David J. Mooney
Lymph nodes (LNs) dynamically expand in response to immunization, but the relationship between LN expansion and the accompanying adaptive immune response is unclear. Here, we first characterized the LN response across time and length scales to vaccin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d79e5a7b54373c251d552b3b4bc52eb0
https://doi.org/10.1101/2022.10.25.513749
https://doi.org/10.1101/2022.10.25.513749
Autor:
Kwasi Adu-Berchie, Joshua M. Brockman, Yutong Liu, David K.Y. Zhang, Alexander J. Najibi, Alexander Stafford, Miguel C. Sobral, Yoav Binenbaum, Maxence O. Dellacherie, David J. Mooney
Adoptive T cell therapy provides the T cell pool needed for immediate tumor debulking, but the infused T cells generally have a narrow repertoire for antigen recognition and limited ability for long-term protection. Here, we present a biomaterial pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37f3030095fe42b9ca7b7e66be395f89
https://doi.org/10.1101/2022.09.10.507437
https://doi.org/10.1101/2022.09.10.507437
Autor:
Hamza Ijaz, Frank R. Urena, Des White, Chyenne D. Yeager, David J. Mooney, Vasanth Chandrasekhar, Alexander G. Stafford, Justin M. Scott, Benjamin T. Seiler, Amanda R. Graveline, Edward J. Doherty, Fernanda Langellotto, Mark Cartwright, Shanda L. Lightbown, Aileen W. Li, Caitlin L. Horgan, Mohan Karkada, Donald E. Ingber, Collin Leese-Thompson, Michael Super, Sami A. Rifai, Maxence O. Dellacherie, Nikolaos Dimitrakakis, Kayla R. Lightbown, Amanda R. Jiang
Publikováno v:
Nature Biomedical Engineering. 6:8-18
Most bacterial vaccines work for a subset of bacterial strains or require the modification of the antigen or isolation of the pathogen before vaccine development. Here we report injectable biomaterial vaccines that trigger potent humoral and T-cell r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10f25a46b11b58f1a23c029f6b1447a5
https://doi.org/10.1038/s41551-021-00756-3
https://doi.org/10.1038/s41551-021-00756-3
Autor:
Alexander J. Najibi, Maxence O. Dellacherie, Ting‐Yu Shih, Edward J. Doherty, Des A. White, Tomás Bauleth‐Ramos, Alexander G. Stafford, James C. Weaver, Chyenne D. Yeager, Benjamin T. Seiler, Matthew Pezone, Aileen W. Li, Bruno Sarmento, Hélder A. Santos, David J. Mooney, Luo Gu
Publikováno v:
Advanced Functional Materials, 32:2110905. WILEY-V C H VERLAG GMBH
Traditional bolus vaccines often fail to sustain robust adaptive immune responses, typically requiring multiple booster shots for optimal efficacy. Additionally, these provide few opportunities to control the resulting subclasses of antibodies produc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a7f37301590bad08754a30b13ae4b0e
https://research.rug.nl/en/publications/a8fe6c37-fe4a-4f6d-81e6-d5fff085ecb2
https://research.rug.nl/en/publications/a8fe6c37-fe4a-4f6d-81e6-d5fff085ecb2
Autor:
Stephanie L. McNamara, Irene de Lázaro, David J. Mooney, Max Darnell, Conor J. Walsh, Bo Ri Seo, Sungmin Nam, Benjamin R. Freedman, Jonathan T. Alvarez, Herman H. Vandenburgh, Maxence O. Dellacherie, Brian J. Kwee, Christopher J. Payne
Publikováno v:
Sci Transl Med
Mechanical stimulation (mechanotherapy) can promote skeletal muscle repair, but a lack of reproducible protocols and mechanistic understanding of the relation between mechanical cues and tissue regeneration limit progress in this field. To address th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8d435f4febdeba08ebc484fa4a15d88
https://pubmed.ncbi.nlm.nih.gov/34613813
https://pubmed.ncbi.nlm.nih.gov/34613813
Autor:
Maxence O. Dellacherie, Sarai Bardales, David J. Mooney, Benjamin T. Seiler, Christina M. Tringides, Hamza Ijaz, Anna N. Honko, Makda S. Gebre, Rebecca I. Johnson, Anthony Griffiths, Tal Gilboa, Jingyou Yu, Dan H. Barouch, Chi-An Cheng, Des White, Mark Cartwright, Edward J. Doherty, Nikolaos Dimitrakakis, Amanda R. Graveline, Fernanda Langellotto, Nadia Storm, David R. Walt, Chyenne D. Yeager
Publikováno v:
Advanced Healthcare Materials
The coronavirus disease 2019 (COVID‐19) pandemic demonstrates the importance of generating safe and efficacious vaccines that can be rapidly deployed against emerging pathogens. Subunit vaccines are considered among the safest, but proteins used in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66cadaaf0d95bf66a32f4d1a698ddfe9
http://europepmc.org/articles/PMC8652677
http://europepmc.org/articles/PMC8652677
Autor:
Alexander J, Najibi, Ting-Yu, Shih, David K Y, Zhang, Junzhe, Lou, Miguel C, Sobral, Hua, Wang, Maxence O, Dellacherie, Kwasi, Adu-Berchie, David J, Mooney
Publikováno v:
Cancer immunology, immunotherapy : CII. 71(12)
Disruption of the tumor extracellular matrix (ECM) may alter immune cell infiltration into the tumor and antitumor T cell priming in the tumor-draining lymph nodes (tdLNs). Here, we explore how intratumoral enzyme treatment (ET) of B16 melanoma tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1b1cdfebf3695cfc1027df89711ca769
https://pubmed.ncbi.nlm.nih.gov/35524791
https://pubmed.ncbi.nlm.nih.gov/35524791