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pro vyhledávání: '"Max-Felix Haering"'
Autor:
Dominik Lutter, Shiho Fujisaka, Kevin Y. Lee, C. Ronald Kahn, Siegfried Ussar, Ning Li, Max-Felix Haering, Lynn Bry, Georg K. Gerber
Publikováno v:
Diabetes
Diabetes 66, 886-896 (2017)
Diabetes 66, 886-896 (2017)
Insulin receptors (IRs) and IGF-I receptors (IGF-IR) are major regulators of metabolism and cell growth throughout the body; however, their roles in the intestine remain controversial. Here we show that genetic ablation of the IR or IGF-IR in intesti
Autor:
C. Ronald Kahn, Shiho Fujisaka, Jeremie Boucher, Jonathon N. Winnay, Antonio R. Perez-Atayde, Max-Felix Haering, Samir Softic, Erica P. Homan, Marie H. Solheim
Publikováno v:
Diabetes
Ectopic lipid accumulation in the liver is an almost universal feature of human and rodent models of generalized lipodystrophy and is also a common feature of type 2 diabetes, obesity, and metabolic syndrome. Here we explore the progression of fatty
Autor:
Yu-Hua Tseng, André Kleinridders, C. Ronald Kahn, Ruidan Xue, Kevin Y. Lee, Simon N. Dankel, Gunnar Mellgren, Jeremie Boucher, Yazmín Macotela, Max-Felix Haering, Thomas Thomou, Siegfried Ussar, Aaron M. Cypess
Publikováno v:
Science Translational Medicine. 6
White, beige, and brown adipocytes are developmentally and functionally distinct but often occur mixed together within individual depots. To target white, beige, and brown adipocytes for diagnostic or therapeutic purposes, a better understanding of t