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Akademický článek

Derivation of novel metabolic pathway score identifies alanine metabolism as a targetable influencer of TNF-alpha signaling

Autor: Brandon N. D'Souza, Manoj Yadav, Prem Prashant Chaudhary, Grace Ratley, Max Yang Lu, Derron A. Alves, Ian A. Myles

Publikováno v: Heliyon, Vol 10, Iss 13, Pp e33502- (2024)

Background: Better understanding of the interaction between metabolism and immune response will be key to understanding physiology and disease. Tumor Necrosis Factor-alpha (TNFα) has been studied widely. However, despite the extensive knowledge abou

Externí odkaz: https://doaj.org/article/1b150bc260df4071bff4fec738a1c426

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Akademický článek

Examining allergy related diseases in Africa: A scoping review protocol.

Autor: Max Yang Lu, Nadia Shobnam, Alicia A Livinski, Sarini Saksena, Dylan Salters, Michelle Biete, Ian A Myles

Publikováno v: PLoS ONE, Vol 19, Iss 2, p e0297949 (2024)

During recent decades, allergy related diseases have emerged as a growing area of concern in developing regions of the world, including Africa. Worldwide prevalence of allergic diseases has grown to an estimated 262 million for asthma, 400 million fo

Externí odkaz: https://doaj.org/article/e482dc8ff83845c99c3ab6d414bfe1f3

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Akademický článek

The role of micro RNAs (miRNAs) in the regulation of Drosophila melanogaster’s innate immunity

Autor: Max Yang Lu, Stanislava Chtarbanova

Publikováno v: Fly, Vol 16, Iss 1, Pp 382-396 (2022)

MicroRNAs (miRNAs) are a class of small non-coding RNAs ~19–22 nt long which post-transcriptionally regulate gene expression. Their ability to exhibit dynamic expression patterns coupled with their wide variety of targets allows miRNAs to regulate

Externí odkaz: https://doaj.org/article/987f25a4a7184630873b270ec0f983f5

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Akademický článek

Updates on the Applications of Spectral Computed Tomography for Musculoskeletal Imaging

Autor: Liesl S. Eibschutz, George Matcuk, Michael Kuo-Jiun Chiu, Max Yang Lu, Ali Gholamrezanezhad

Publikováno v: Diagnostics, Vol 14, Iss 7, p 732 (2024)

Spectral CT represents a novel imaging approach that can noninvasively visualize, quantify, and characterize many musculoskeletal pathologies. This modality has revolutionized the field of radiology by capturing CT attenuation data across multiple en

Externí odkaz: https://doaj.org/article/f09c83ed71a2437baa83d147458a4554

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Akademický článek

Isogenic human SNCA gene dosage induced pluripotent stem cells to model Parkinson’s disease

Autor: Faria Zafar, Vasavi Nallur Srinivasaraghavan, Max Yang Chen, C. Alejandra Morato Torres, Birgitt Schüle

Publikováno v: Stem Cell Research, Vol 60, Iss , Pp 102733- (2022)

Alpha-synuclein overexpression and aggregation are critical factors in the pathogenesis of Parkinson’s disease (PD). Clinical cases with alpha-synuclein (SNCA) multiplications or deletions indicate that gene expression levels are essential for neur

Externí odkaz: https://doaj.org/article/460e4237bc484f0993b82d999b252275

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