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pro vyhledávání: '"Max Wrobbel"'
Autor:
Hannah Karp, J. Carter Ralphe, Zachery R. Gregorich, Willem J. de Lange, Timothy J. Kamp, Ying Ge, Elizabeth F. Bayne, Trisha Tucholski, Wenxuan Cai, Joshua L. Hermsen, Sean J. McIlwain, Amy Li, Steven B. Marston, Stanford D. Mitchell, Petr G. Vikhorev, Zachary Hite, Cristobal G. dos Remedios, Max Wrobbel, Sean Lal, Takushi Kohmoto, Richard L. Moss
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Hypertrophic cardiomyopathy (HCM) is a common genetic heart disease and a leading cause of sudden cardiac death in young adults. HCM has been linked to mutations in genes encoding sarcomeric proteins, but how different mutations can resu