Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Max W Chang"'
Autor:
Juan García-Bernalt Diego, Gagandeep Singh, Sonia Jangra, Kim Handrejk, Manon Laporte, Lauren A Chang, Sara S El Zahed, Lars Pache, Max W Chang, Prajakta Warang, Sadaf Aslam, Ignacio Mena, Brett T Webb, Christopher Benner, Adolfo García-Sastre, Michael Schotsaert
Publikováno v:
PLoS Pathogens, Vol 20, Iss 1, p e1011805 (2024)
Hybrid immunity (vaccination + natural infection) to SARS-CoV-2 provides superior protection to re-infection. We performed immune profiling studies during breakthrough infections in mRNA-vaccinated hamsters to evaluate hybrid immunity induction. The
Externí odkaz:
https://doaj.org/article/b8157faea3be4694babe8d2522d568aa
Autor:
William F Flynn, Max W Chang, Zhiqiang Tan, Glenn Oliveira, Jinyun Yuan, Jason F Okulicz, Bruce E Torbett, Ronald M Levy
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 4, p e1004249 (2015)
While the role of drug resistance mutations in HIV protease has been studied comprehensively, mutations in its substrate, Gag, have not been extensively cataloged. Using deep sequencing, we analyzed a unique collection of longitudinal viral samples f
Externí odkaz:
https://doaj.org/article/2c755f76f6a4487586e7afbbfde7fc7d
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e11955 (2010)
The AutoDock family of software has been widely used in protein-ligand docking research. This study compares AutoDock 4 and AutoDock Vina in the context of virtual screening by using these programs to select compounds active against HIV protease.Both
Externí odkaz:
https://doaj.org/article/6c3ef5e398554d1ab681a253d27576ea
Autor:
Ana Carolina Dantas Machado, Steven D. Brown, Amulya Lingaraju, Vignesh Sivaganesh, Cameron Martino, Amandine Chaix, Peng Zhao, Antonio F.M. Pinto, Max W. Chang, R. Alexander Richter, Alan Saghatelian, Alan R. Saltiel, Rob Knight, Satchidananda Panda, Amir Zarrinpar
Publikováno v:
Cell Reports, Vol 40, Iss 1, Pp 111008- (2022)
Summary: Compositional oscillations of the gut microbiome are essential for normal peripheral circadian rhythms, both of which are disrupted in diet-induced obesity (DIO). Although time-restricted feeding (TRF) maintains circadian synchrony and prote
Externí odkaz:
https://doaj.org/article/5d7baa7f81854be59e805862d41bfb1b
Autor:
Bastian Ramms, Sohan Patel, Chelsea Nora, Ariane R. Pessentheiner, Max W. Chang, Courtney R. Green, Gregory J. Golden, Patrick Secrest, Ronald M. Krauss, Christian M. Metallo, Christopher Benner, Veronica J. Alexander, Joseph L. Witztum, Sotirios Tsimikas, Jeffrey D. Esko, Philip L.S.M. Gordts
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 8, Pp 1379-1395 (2019)
Hypertriglyceridemia results from accumulation of triglyceride (TG)-rich lipoproteins (TRLs) in the circulation and is associated with increased CVD risk. ApoC-III is an apolipoprotein on TRLs and a prominent negative regulator of TG catabolism. We r
Externí odkaz:
https://doaj.org/article/79b2fc472cb54420abab601c33268491
Autor:
Amir Zarrinpar, Amandine Chaix, Zhenjiang Z. Xu, Max W. Chang, Clarisse A. Marotz, Alan Saghatelian, Rob Knight, Satchidananda Panda
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Antibiotic-induced microbiome depletion is one of the most common approaches to modulate the gut microbiome. Here the authors demonstrate that it affects gut homeostasis and glucose metabolism by decreasing luminal short chain fatty acids and leading
Externí odkaz:
https://doaj.org/article/a5e2a93dd23c4ffd9f9cfa80ad8db294
Autor:
Courtney Nguyen, Danielle L. Swaney, Lars Pache, Hong M. Moulton, David A. Stein, Shashank Tripathi, Dexter Pratt, Trey Ideker, Stephen Soonthornvacharin, David Jimenez-Morales, Maite Sanchez-Aparicio, Nish Beltran-Raygoza, Paul D. De Jesus, Randy A. Albrecht, Kelsey M. Haas, Adolfo García-Sastre, Judd F. Hultquist, João I. Mamede, Guojun Wang, Laura Martin-Sancho, Ariel Rodriguez-Frandsen, Christopher Churas, Max W. Chang, Sara Brin Rosenthal, Thong T. Nguyen, Nevan J. Krogan, Sumit K. Chanda, Michael J. McGregor, Laura Riva, Christopher Benner
Publikováno v:
Nature microbiology, vol 6, iss 10
Nat Microbiol
Nat Microbiol
The fate of influenza A virus (IAV) infection in the host cell depends on the balance between cellular defence mechanisms and viral evasion strategies. To illuminate the landscape of IAV cellular restriction, we generated and integrated global geneti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13b8b7933cc7d6e1aee1e78f2f5ec156
https://doi.org/10.1038/s41564-021-00964-2
https://doi.org/10.1038/s41564-021-00964-2
Autor:
Laura Riva, Shuofeng Yuan, Xin Yin, Laura Martin-Sancho, Naoko Matsunaga, Lars Pache, Sebastian Burgstaller-Muehlbacher, Paul D. De Jesus, Peter Teriete, Mitchell V. Hull, Max W. Chang, Jasper Fuk-Woo Chan, Jianli Cao, Vincent Kwok-Man Poon, Kristina M. Herbert, Kuoyuan Cheng, Tu-Trinh H. Nguyen, Andrey Rubanov, Yuan Pu, Courtney Nguyen, Angela Choi, Raveen Rathnasinghe, Michael Schotsaert, Lisa Miorin, Marion Dejosez, Thomas P. Zwaka, Ko-Yung Sit, Luis Martinez-Sobrido, Wen-Chun Liu, Kris M. White, Mackenzie E. Chapman, Emma K. Lendy, Richard J. Glynne, Randy Albrecht, Eytan Ruppin, Andrew D. Mesecar, Jeffrey R. Johnson, Christopher Benner, Ren Sun, Peter G. Schultz, Andrew I. Su, Adolfo García-Sastre, Arnab K. Chatterjee, Kwok-Yung Yuen, Sumit K. Chanda
Publikováno v:
Nature
Summary The emergence of the novel SARS coronavirus 2 (SARS-CoV-2) in 2019 has triggered an ongoing global pandemic of severe pneumonia-like disease designated as coronavirus disease 2019 (COVID-19)1. The development of a vaccine is likely to require
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aec8b07864daa4712214c5022636c8e8
https://doi.org/10.1038/s41586-020-2577-1
https://doi.org/10.1038/s41586-020-2577-1
Autor:
Sascha H. Duttke, Patricia Montilla-Perez, Max W. Chang, Hairi Li, Hao Chen, Lieselot L. G. Carrette, Giordano de Guglielmo, Olivier George, Abraham A. Palmer, Christopher Benner, Francesca Telese
Publikováno v:
Frontiers in neuroscience. 16
Substance abuse and addiction represent a significant public health problem that impacts multiple dimensions of society, including healthcare, the economy, and the workforce. In 2021, over 100,000 drug overdose deaths were reported in the US, with an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99751fa793146fe057ef7546ea5f63ac
https://pubmed.ncbi.nlm.nih.gov/35651629
https://pubmed.ncbi.nlm.nih.gov/35651629
Autor:
Slim Fourati, David Jimenez-Morales, Judd Hultquist, Max W. Chang, Christopher Benner, Nevan Krogan, Lars Pache, Sumit Chanda, Rafick-Pierre Sekaly, Adolfo García-Sastre, Melissa B. Uccellini
Ly6Chi inflammatory monocytes show high IFN responses, and contribute to both protective and pathogenic functions following influenza virus infection. In order to understand the significance of IFN responses in this subset, we examined monocytes duri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17866d5b508612e31258f8a9ccbccc4d
https://doi.org/10.1101/2022.01.10.475751
https://doi.org/10.1101/2022.01.10.475751
