Comprehensive Analysis of Germline Variants in Mexican Patients with Hereditary Breast and Ovarian Cancer Susceptibility

Autor: Víctor Hugo Garzón Barrientos, Luis A. Herrera, Lizbeth García Esquivel, Ernesto Arturo Rojas Jiménez, Verónica Fragoso Ontiveros, Cecilia Frecha, Oscar Moreno García, Perla Karina Espino Silva, Gabriela Torres Mejia, Rosalía Quezada Urban, Luis I. Terrazas, Andrea Figueroa Morales, Luis Enrique Romero Cruz, Javier Oliver, María Patricia Rojo Castillo, Felipe Vaca Paniagua, Virginia Jan, Clara Estela Díaz Velásquez, Jorge Haro-Santa Cruz, Michael Dean, Pablo Ruiz Flores, Rosa María Álvarez Gómez, Isabelle Romieu, Claudia Fabiola Méndez Catalá, Yolanda I. Chirino, Héctor Martínez Gregorio, Hector Lopez, Fernando Rodríguez León, Rina Gitler, Iván Delgado Enciso, Sandra Perdomo, Max Sirota Toporek

Publikováno v: Cancers
Volume 10
Issue 10
Repositorio U. El Bosque
Universidad El Bosque
instacron:Universidad El Bosque
Cancers, Vol 10, Iss 10, p 361 (2018)

Hereditary breast and ovarian cancer syndrome (HBOC) represents 5–10% of all patients with breast cancer and is associated with high-risk pathogenic alleles in BRCA1/2 genes, but only for 25% of cases. We aimed to find new pathogenic alleles in a p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5d48203ef7109d612a01162a067b496
https://doi.org/10.3390/cancers10100361

Abstract 2545: Identification of germline pathogenic alleles in 143 cancer predisposing genes in Mexican patients with hereditary breast cancer by massive parallel sequencing

Autor: Oscar Moreno-García, Luis I. Terrazas, Maria Patricia Rojo-Castillo, Ivan Delgado-Enciso, Lizzette Sabrina De Hoyos-Arévalo, Victor Hugo Garzón-Barrientos, Max Sirota-Toporek, Clara Díaz-Velásquez, Rosalía Quezada-Urban, Felipe Vaca-Paniagua, Rina Gitler, Fernando Mainero-Ratchelous, Andrea Figueroa-Morales

Publikováno v: Cancer Research. 76:2545-2545

Breast cancer is the neoplastic disease with the highest incidence and mortality worldwide and nearly 10% of the cases are due to inherited pathogenic alleles in cancer predisposing genes such as BRCA1 and BRCA2. However, the spectrum of inherited br

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0e915aecd06404056b72a199f5b25a90
https://doi.org/10.1158/1538-7445.am2016-2545

Feasibility of a breast health educational program to increase breast cancer awareness among adolescents and their female relatives in low-income communities

Autor: Ana Fs Martinez-Aviles, Yanin Chavarri Guerra, Arti Hurria, Enrique Soto Perez De Celis, Andrea Salazar-Moreno, Edgar Baltazar-Avalos, Brenda Cosme-Gonzalez, Julia A Melendez-Rosas, David D. Smith, Max Sirota-Toporek, Sofia N Gallegos-Quintana, Alba M Pavas-Vivas, Alejandro Mohar, Mayte Ayala-Gonzalez, Patricia Rojo-Castillo, Martin A Reyes-Bautista, Rina Gitler-Weingarten, Viridiana Chaveste-Ramos

Publikováno v: Journal of Clinical Oncology. 33:76-76

76 Background: Delays in the diagnosis of breast cancer in developing countries are partially related to a lack of knowledge on breast health (BH), particularly in rural communities with poor access to education. We implemented a BH educational progr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fdaacf9d1990347507109eaee74c8b90
https://doi.org/10.1200/jco.2015.33.28_suppl.76