Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Max Seidy Saito"'
Autor:
André Luiz Lourenço, Max Seidy Saito, Luís Eduardo Gomes Dorneles, Gil Mendes Viana, Plínio Cunha Sathler, Lúcia Cruz de Sequeira Aguiar, Marcelo de Pádula, Thaisa Francielle Souza Domingos, Aline Guerra Manssour Fraga, Carlos Rangel Rodrigues, Valeria Pereira de Sousa, Helena Carla Castro, Lucio Mendes Cabral
Publikováno v:
Molecules, Vol 20, Iss 4, Pp 7174-7200 (2015)
The incidence of hematological disorders has increased steadily in Western countries despite the advances in drug development. The high expression of the multi-resistance protein 4 in patients with transitory aspirin resistance, points to the importa
Externí odkaz:
https://doaj.org/article/16d481e62d404d4983b4926b942fd102
Autor:
Thatyana R. A. Vasconcelos, Solange M. S. V. Wardell, Paola de S. Sanches, Viviane de Oliveira Freitas Lione, Ana Joffily, Marcos da Veiga Kalil, Gabriela Cristina de Carvalho Silva, Max Seidy Saito, Luciana Terra, Claudia R. B. Gomes, Plínio Cunha Sathler, James L. Wardell, Helena Carla Castro, Marcus V. N. de Souza, Eliza de L. Chazin
Publikováno v:
Medicinal Chemistry. 14:304-310
Background Over the last few years, fungal infections have emerged as a worrisome global public health problem. Candidiasis is a disease caused by Candida species and has been a problem worldwide mainly for immunosuppressed patients. Lately, the resi
Autor:
Max Seidy Saito, Hye Chung Kang, Helena Carla Castro, Plínio Cunha Sathler, Lucio Mendes Cabral, André Luiz Lourenço, Ana P G Arêas, Carlos Rangel Rodrigues
Publikováno v:
Archives of Biological Sciences, Vol 68, Iss 2, Pp 325-331 (2016)
The potential of antioxidants as tools for lowering the incidence of diseases, including cardiovascular events, is of growing interest. Some antioxidants (e.g. vitamin E and acetyl-salicylic acid) have been described as effective on cardiovascular di
Autor:
Robson Q. Monteiro, Jéssica V. Faria, Percilene Fazolin Vegi, André Luiz Lourenço, Tatiana P. Dutra, Alice M. R. Bernardino, Carlos Rangel Rodrigues, Max Seidy Saito, Marcos Vinicius Santana, Helena Carla Castro, Maurício S. dos Santos, Plínio Cunha Sathler, Gustavo S. P. Pinto
Publikováno v:
Journal of the Brazilian Chemical Society.
This article reports a novel virtual screening algorithm seeking the rational identification of novel lead anticoagulants. Seven 5-(3-methyl-1-aryl-1H-pyrazol-4-yl)-1H-tetrazoles and seven novel 1-aryl-4-(4,5-dihydro-1H-imidazol-2-yl)-3-methyl-1H-pyr
Autor:
Carlos Rangel Rodrigues, Thaisa Francielle Souza Domingos, Max Seidy Saito, Gil Mendes Viana, Lucia C. S. Aguiar, André Luiz Lourenço, Plínio Cunha Sathler, Valeria Pereira de Sousa, Lucio Mendes Cabral, Luís Eduardo Gomes Dorneles, Aline Guerra Manssour Fraga, Helena Carla Castro, Marcelo de Pádula
Publikováno v:
Molecules, Vol 20, Iss 4, Pp 7174-7200 (2015)
Molecules
Volume 20
Issue 4
Pages 7174-7200
Molecules
Volume 20
Issue 4
Pages 7174-7200
The incidence of hematological disorders has increased steadily in Western countries despite the advances in drug development. The high expression of the multi-resistance protein 4 in patients with transitory aspirin resistance, points to the importa
Autor:
André Luiz Lourenço, Charles S. Craik, Leonardo A. Silva, Max Seidy Saito, Alessandra Mendonça Teles de Souza, Maria A.F. Vera, Juliana da Fonseca Rezende e Mello, Raquel R.S. Salvador, Estela M.F. Muri, Plínio Cunha Sathler, Lucio Mendes Cabral, Helena Carla Castro, Carlos Rangel Rodrigues, Luiza R.S. Dias
Publikováno v:
European journal of medicinal chemistry. 135
Cardiovascular diseases (CVDs) account for over 17 million deaths globally each year, with atherosclerosis as the underlying cause of most CVDs. Herein we describe the synthesis and in vitro mechanistic evaluation of novel N'-benzylidene-carbohydrazi
Autor:
André Luiz Lourenço, Plínio Cunha Sathler, Reinaldo B Geraldo, Lucio Mendes Cabral, Helena Carla Castro, Pabulo Henrique Rampelotto, Max Seidy Saito
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 10, Pp 17901-17919 (2014)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Platelets are cytoplasmatic fragments from bone marrow megakaryocytes present in blood. In this work, we review the basis of platelet mechanisms, their participation in syndromes and in arterial thrombosis, and their potential as a target for designi
Autor:
Magaly Girão Albuquerque, Helena Carla Castro, Plínio Cunha Satlher, André Luiz Lourenço, Carlos Rangel Rodrigues, Maíra Ingrid Vitorino, Max Seidy Saito, Lucio Mendes Cabral, Eliane Pedra Dias, Antonio C. C. Freitas, Luiza R.S. Dias
Publikováno v:
Journal of enzyme inhibition and medicinal chemistry. 31(6)
Platelet aggregation is one of the main events involved in vascular thrombus formation. Recently, N'-substituted-phenylmethylene-3-methyl-1,6-diphenyl-1H-pyrazolo[3,4-b]pyridine-4-carbohydrazides were described as antiplatelet derivatives. In this wo