Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Max Mossner"'
Autor:
Claudia D. Baldus, Julia Thibaut, Nicola Goekbuget, Andrea Stroux, Cornelia Schlee, Max Mossner, Thomas Burmeister, Stefan Schwartz, Clara D. Bloomfield, Dieter Hoelzer, Eckhard Thiel, Wolf-Karsten Hofmann
Publikováno v:
Haematologica, Vol 94, Iss 10 (2009)
Background NOTCH1 mutations have been associated with a favorable outcome in pediatric acute T-lymphoblastic leukemia. However, the results of studies on the prognostic significance of NOTCH1 mutations in adult T-lymphoblastic leukemia remain controv
Externí odkaz:
https://doaj.org/article/f243d803531449688bc9d3abdc45bcf0
Autor:
Melissa Barroux, Jacob Househam, Eszter Lakatos, Tahel Ronel, Ann-Marie Baker, Henrike Salié, Max Mossner, Kane Smith, Chris Kimberley, Salpie Nowinski, Alison Berner, Vinaya Gunasri, Marnix Jansen, Giulio Caravagna, Katja Steiger, Julia Slotta-Huspenina, Wilko Weichert, Markus Alberstmeier, Benny Chain, Helmut Friess, Bertram Bengsch, Roland Schmid, Jens Siveke, Michael Quante, Trevor Graham
Locally advanced oesophageal adenocarcinoma (EAC) remains difficult to treat because of common resistance to neoadjuvant therapy and high recurrence rates. The ecological and evolutionary dynamics responsible for treatment failure are incompletely un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23626ec121eaf552ab7c2479aaea43d5
https://doi.org/10.21203/rs.3.rs-2738048/v1
https://doi.org/10.21203/rs.3.rs-2738048/v1
Autor:
Melissa Barroux, Jacob Househam, Eszter Lakatos, Tahel Ronel, Ann-Marie Baker, Henrike Salié, Max Mossner, Kane Smith, Chris Kimberley, Salpie Nowinski, Alison Berner, Vinaya Gunasri, Marnix Jansen, Giulio Caravagna, Julia Slotta-Huspenina, Wilko Weichert, Markus Alberstmeier, Benny Chain, Helmut Friess, Bertram Bengsch, Roland M. Schmid, Jens T. Siveke, Michael Quante, Trevor A. Graham
Publikováno v:
Cancer Research. 83:4539-4539
Introduction: Locally advanced esophageal adenocarcinoma (EAC) remains difficult to treat, and resistance is common. The ecological and evolutionary dynamics responsible for treatment failure are incompletely understood. Aim & Methods: We performed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e2b590a422a5b3fe8319f2a45ca6b2d
https://doi.org/10.1158/1538-7445.am2023-4539
https://doi.org/10.1158/1538-7445.am2023-4539
Autor:
Miriam Mitchinson, Giulio Caravagna, Luca Magnani, Chris Kimberley, Chris P. Barnes, John Bridgewater, Inmaculada Spiteri, Calum Gabbutt, Melissa Schmidt, Alison May Berner, Manuel Rodriguez-Justo, Marnix Jansen, Claire Lynn, Max Mossner, Chela James, Daniele Ramazzotti, Luis Zapata, Jacob Househam, Bingjie Chen, Alessandro Vinceti, Darryl Shibata, Helena Costa, George D. Cresswell, Ann-Marie Baker, Benjamin Werner, Timon Heide, Francesco Iorio, Eszter Lakatos, Javier Fernández-Mateos, Andrea Sottoriva, Trevor A. Graham, Daniel Nichol
Cancer genomic medicine relies on targeting driver genes. However, current catalogues of cancer drivers are mostly based on indirect measurements of mutation frequencies, positions or types, rather than their effect on clonal expansionsin vivo. Moreo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::086556328d77d35edfc59a809cb8cf92
https://doi.org/10.1101/2021.07.14.451265
https://doi.org/10.1101/2021.07.14.451265
Autor:
Timon Heide, Jacob Househam, George D Cresswell, Inmaculada Spiteri, Claire Lynn, Max Mossner, Chris Kimberley, Javier Fernandez-Mateos, Bingjie Chen, Luis Zapata, Chela James, Iros Barozzi, Ketevan Chkhaidze, Daniel Nichol, Alison Berner, Melissa Schmidt, Eszter Lakatos, Ann-Marie Baker, Helena Costa, Miriam Mitchinson, Marnix Jansen, Giulio Caravagna, Daniele Ramazzotti, Darryl Shibata, John Bridgewater, Manuel Rodriguez-Justo, Luca Magnani, Trevor A Graham, Andrea Sottoriva
Colorectal malignancies are a leading cause of cancer death. Despite large-scale genomic efforts, DNA mutations do not fully explain malignant evolution. Here we study the co-evolution of the genome and epigenome of colorectal tumours at single-clone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75ddc160c744d9e0dad51d06f2c2b475
https://doi.org/10.1101/2021.07.12.451121
https://doi.org/10.1101/2021.07.12.451121
Autor:
Max Mossner, Q. Xu, Iris Palme, Julia Obländer, N. Weimer, Daniel Nowak, Johanna Flach, Georgia Metzgeroth, A. Darwich, Verena Nowak, Eva Altrock, A. Streuer, Johann-Christoph Jann, W.-K. Hofmann, V. Ryabov, Nanni Schmitt, Florian Nolte, Ahmed Jawhar
Publikováno v:
Leukemia Research. 108:106680.2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca1c47a3c2b3e2fcd2dcc2568a0c1c18
https://doi.org/10.1016/j.leukres.2021.106680.2
https://doi.org/10.1016/j.leukres.2021.106680.2
Autor:
Cornelia Schlee, Arend Bohne, Eckhard Thiel, Wolf-Karsten Hofmann, Max Mossner, Claudia D. Baldus, Julia Thibaut, Sandra Heesch
Publikováno v:
Leukemia Research. 33:817-822
Expression of ERG is of prognostic significance in acute myeloid leukemia (AML) and T-lymphoblastic leukemia (T-ALL) pointing to its role in leukemogenesis. To unravel its transcriptional regulation we analyzed the expression of ERG specific isoforms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6ccdeaada8c8b6f17fd73fb33205b59
https://doi.org/10.1016/j.leukres.2008.11.012
https://doi.org/10.1016/j.leukres.2008.11.012
Autor:
Thomas Luft, Anthony D. Ho, Daniel Nowak, Christine Folz, Florian Nolte, Tobias Boch, Max Mossner, Jennifer Klemmer, Johann Christoph Jann, Harald Fricke, Claudia Kunz, Wolf-Karsten Hofmann, Susanne Brendel
Publikováno v:
Journal of Clinical Oncology. 34:e18552-e18552
e18552Background: Myelodysplastic syndromes (MDS) are characterized by ineffective hematopoiesis resulting in peripheral cytopenia. In low risk MDS, a pro-apoptotic milieu was found with increased ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d05b223f6a46c3f682e7c74bd9e9061b
https://doi.org/10.1200/jco.2016.34.15_suppl.e18552
https://doi.org/10.1200/jco.2016.34.15_suppl.e18552
Autor:
Andreas Hochhaus, Wolf-Karsten Hofmann, Thomas Ernst, Philipp Erben, Susanne Schnittger, Juliana Schwaab, Georgia Metzgeroth, Andreas Reiter, Philipp Ströbel, Torsten Haferlach, Jenny Rinke, Nicholas C.P. Cross, Max Mossner
Publikováno v:
Annals of hematology. 91(11)
Activating point mutations in CBL have recently been identified in diverse subtypes of myeloid neoplasms. Because detailed clinical and hematological characteristics of CBL-mutated cases is lacking, we screened 156 BCR-ABL and JAK2 V617F negative pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97033edd15b9616342d574eace94601e
https://pubmed.ncbi.nlm.nih.gov/23010802
https://pubmed.ncbi.nlm.nih.gov/23010802
Autor:
Wolf-Karsten Hofmann, Claudia D. Baldus, Julia Thibaut, Cornelia Schlee, Andrea Stroux, Dieter Hoelzer, Max Mossner, Stefan Schwartz, Clara D. Bloomfield, Eckhard Thiel, Nicola Goekbuget, Thomas Burmeister
Publikováno v:
Haematologica. 94(10)
Background NOTCH1 mutations have been associated with a favorable outcome in pediatric acute T-lymphoblastic leukemia. However, the results of studies on the prognostic significance of NOTCH1 mutations in adult T-lymphoblastic leukemia remain controv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::604c71da0138e222ff27fede53042c4d
https://pubmed.ncbi.nlm.nih.gov/19794079
https://pubmed.ncbi.nlm.nih.gov/19794079