Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Max M. L. Knott"'
Autor:
Martin F. Orth, Florencia Cidre-Aranaz, Laura Romero-Pérez, G. Ammirati, Felix Bestvater, T. G. P. Gruenewald, S. Bersini, Max M. L. Knott, Chiara Arrigoni, Julian Musa, Martha J. Carreño-Gonzalez, Roland Imle, Matteo Moretti, S. Kutschmann, Shunya Ohmura, Aruna Marchetto, Jing Li, Cornelius M. Funk, Thomas Kirchner, Ana Banito, Katharina Ceranski, Merve Kasan, Tilman L. B. Hoelting
Identification of cancer stemness genes is crucial to understanding the underlying biology of therapy resistance, relapse, and metastasis. Ewing sarcoma (EwS) is the second most common bone tumor in children and adolescents. It is a highly aggressive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba2fe0b3194430af0e0271795e84b3c8
https://doi.org/10.1101/2021.02.25.432862
https://doi.org/10.1101/2021.02.25.432862
Publikováno v:
Advances in experimental medicine and biology. 1231
T cell-mediated elimination of malignant cells is one cornerstone of endogenous and therapeutically induced antitumor immunity. Tumors exploit numerous regulatory mechanisms to suppress T cell immunity. Regulatory T cells (T regs) play a crucial role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::021b798c076ef3ce43a931101447409c
https://pubmed.ncbi.nlm.nih.gov/32060848
https://pubmed.ncbi.nlm.nih.gov/32060848
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030366667
T cell-mediated elimination of malignant cells is one cornerstone of endogenous and therapeutically induced antitumor immunity. Tumors exploit numerous regulatory mechanisms to suppress T cell immunity. Regulatory T cells (T regs) play a crucial role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9be0ec6838377b435b159c4a868037f0
https://doi.org/10.1007/978-3-030-36667-4_8
https://doi.org/10.1007/978-3-030-36667-4_8
Publikováno v:
Future Oncology. 12:1-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::120add8798fde150ee182c24ec6c8e8b
https://doi.org/10.2217/fon.15.298
https://doi.org/10.2217/fon.15.298
Autor:
Max M. L. Knott, Moritz Rapp, Raffael Thaler, Dominik Lisowski, David Anz, Susanne Stutte, Wolfgang G. Kunz, Patrick Layritz, Natascha Röhrle, Maximilian W.M. Wintergerst, Carole Bourquin, Bastian Meyer, Stefan Endres, Sascha Haubner, Ulrich H. von Andrian, Ignazio Piseddu, Simon Grassmann, Stefan Moder, Stephan Eiber, Benjamin Kühnemuth, Viola Vetter
Publikováno v:
The Journal of Experimental Medicine
Journal of Experimental Medicine (2019)
Journal of Experimental Medicine (2019)
Rapp et al. demonstrate that dendritic cells in the lymph node secrete CCL22 to build cell–cell contacts with CCR4-expressing regulatory T cells, leading to immune suppression. Conversely, CCL22 deficiency results in enhanced T cell immunity, shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5d66c5c42af97bf53bba3283fe57d7
https://mediatum.ub.tum.de/1539462
https://mediatum.ub.tum.de/1539462
Autor:
Stephan Kruger, Raffael Thaler, Viola Vetter, David Anz, Doris Mayr, Patrick Layritz, Moritz Rapp, Benjamin Kühnemuth, Gabriela M. Wiedemann, Steffen Ormanns, Julia Fesseler, Stefan Endres, Sascha Haubner, Max M. L. Knott
In cancer patients, immunosuppression through regulatory T cells (Treg) is a crucial component of tumor immune evasion and contributes to disease progression. Tumor-infiltrating Treg in particular suppress local effector T cell responses and are asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54a15b49a2dbcba3b517e910b9e58c9f
https://europepmc.org/articles/PMC5048775/
https://europepmc.org/articles/PMC5048775/
Autor:
Michaela Golic, Veit Hornung, Sarah Nagel, Simon Rothenfusser, Max M. L. Knott, Franz Bauernfeind, Viktor H. Koelzer, Stephan Eiber, Stefan Endres, Carole Bourquin, Raffael Thaler, Sascha Haubner, Cornelia Wurzenberger, Gabriela M. Wiedemann, David Anz, Doris Mayr, Christoph Scholz, Moritz Rapp
Publikováno v:
Cancer research. 75(21)
The chemokine CCL22 is abundantly expressed in many types of cancer and is instrumental for intratumoral recruitment of regulatory T cells (Treg), an important subset of immunosuppressive and tumor-promoting lymphocytes. In this study, we offer evide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d2af70acd0addda746a25893ee1df9d
https://pubmed.ncbi.nlm.nih.gov/26432403
https://pubmed.ncbi.nlm.nih.gov/26432403