Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Max J. Bedward"'
Autor:
Yichen Zhong, Hakimeh Moghaddas Sani, Bishnu P. Paudel, Jason K. K. Low, Ana P. G. Silva, Stefan Mueller, Chandrika Deshpande, Santosh Panjikar, Xavier J. Reid, Max J. Bedward, Antoine M. van Oijen, Joel P. Mackay
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
CHD4 is an essential chromatin remodelling enzyme in complex organisms. Here the authors demonstrate that CHD4 activity is regulated both positively and negatively by distinct auxiliary domains, revealing parallels with other chromatin remodellers.
Externí odkaz:
https://doaj.org/article/344de9654b7241baa0c94cef93c12913
Autor:
Yichen Zhong, Bishnu P. Paudel, Daniel P. Ryan, Jason K. K. Low, Charlotte Franck, Karishma Patel, Max J. Bedward, Mario Torrado, Richard J. Payne, Antoine M. van Oijen, Joel P. Mackay
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Chromatin remodellers hydrolyse ATP to move nucleosomal DNA against histone octamers. Here, the authors use single-molecule assays to examine the mechanism of action of CHD4 remodeller, and provide evidence that CHD4 slides nucleosomes by decoupling
Externí odkaz:
https://doaj.org/article/848eae28baf44153b8dee9ed3f4508b7
Autor:
Max J. Bedward, Joel P. Mackay, K. Patel, Bishnu P. Paudel, Antoine M. van Oijen, Charlotte Franck, Richard J. Payne, Jason Low, Yichen Zhong, Daniel P. Ryan, Mario Torrado
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Chromatin remodellers hydrolyse ATP to move nucleosomal DNA against histone octamers. The mechanism, however, is only partially resolved, and it is unclear if it is conserved among the four remodeller families. Here we use single-molecule assays to e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef0013d91c279270332813f0a10bd7b8
https://doi.org/10.1038/s41467-020-15183-2
https://doi.org/10.1038/s41467-020-15183-2
Autor:
Max J. Bedward, Jason Low, Yichen Zhong, K. Patel, Bishnu P. Paudel, Antoine M. van Oijen, Charlotte Franck, Daniel P. Ryan, Joel P. Mackay, Richard J. Payne
SummaryChromatin remodellers hydrolyse ATP to move nucleosomal DNA against histone octamers. The mechanism, however, is only partially resolved, and unclear if it is conserved among the four remodeller families. Here we use single-molecule assays to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c30a87932cdd8d424ff0198d9d4ea988
https://doi.org/10.1101/684860
https://doi.org/10.1101/684860
Autor:
Joel P. Mackay, David C. Williams, Mehdi Sharifi Tabar, Nicholas E. Shepherd, Courtney S. Winning, Ana P. G. Silva, Jason Low, Cherry Kwong, Musa E. Isilak, Maryam Sana, Max J. Bedward, Mary J. Sperlazza, Mario Torrado, Jason W. Schmidberger
Publikováno v:
The FEBS journal. 284(24)
The nucleosome remodelling and deacetylase (NuRD) complex is essential for the development of complex animals. NuRD has roles in regulating gene expression and repairing damaged DNA. The complex comprises at least six proteins with two or more paralo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39f2b3293a5abd4a1990257151cead7b
https://pubmed.ncbi.nlm.nih.gov/29063705
https://pubmed.ncbi.nlm.nih.gov/29063705