Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Max J. Bedding"'
Autor:
Anthony J. O’Donoghue, Michael C Yoon, Max J. Bedding, Vivian Hook, Pavla Fajtová, Arthur H Tang, Mark Larance, Linfeng Li, Chien-Te Tseng, Stuart Turville, James H. McKerrow, Dustin Pwee, Laura Beretta, Alexander Stoye, Danielle E. Skinner, William H. Gerwick, Anneliese S. Ashhurst, Thomas D. Meek, Anupriya Aggarwal, Aleksandra Drelich, Richard J. Payne
Publikováno v:
bioRxiv
Cathepsin L is a key host cysteine protease utilized by coronaviruses for cell entry and is a promising drug target for novel antivirals against SARS-CoV-2. The marine natural product gallinamide A and several synthetic analogues were identified as p
Publikováno v:
Methods in enzymology. 662
Peptides and proteins represent an important class of biomolecules responsible for a plethora of structural and functional roles in vivo. Following their translation on the ribosome, the majority of eukaryotic proteins are post-translationally modifi
Autor:
Jason Johansen-Leete, Sven Ullrich, Sarah E. Fry, Rebecca Frkic, Max J. Bedding, Anupriya Aggarwal, Anneliese S. Ashhurst, Kasuni B. Ekanayake, Mithun C. Mahawaththa, Vishnu M. Sasi, Stephanie Luedtke, Daniel J. Ford, Anthony J. O'Donoghue, Toby Passioura, Mark Larance, Gottfried Otting, Stuart Turville, Colin J. Jackson, Christoph Nitsche, Richard J. Payne
Antivirals that specifically target SARS-CoV-2 are needed to control the COVID-19 pandemic. The main protease (Mpro) is essential for SARS-CoV-2 replication and is an attractive target for antiviral development. Here we report the use of the Random n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beb19951e5ab5d8ede201d6868c3b957
https://hdl.handle.net/2123/28987
https://hdl.handle.net/2123/28987
Publikováno v:
Methods in Enzymology ISBN: 9780323907354
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::465845b9c0b5cc736666c405ddd8ac19
https://doi.org/10.1016/bs.mie.2021.10.017
https://doi.org/10.1016/bs.mie.2021.10.017
Autor:
Yichen Zhong, Max J. Bedding, Richard J. Payne, Stephen A. Byrne, Daniel J Ford, Joel P. Mackay, Leo Corcilius, Charlotte Franck, Mark Larance
Publikováno v:
Chemical Science
The modification of peptides and proteins has emerged as a powerful means to efficiently prepare high value bioconjugates for a range of applications in chemical biology and for the development of next-generation therapeutics. Herein, we report a nov
Autor:
Rebecca L. Frkic, Sarah E. Fry, Anneliese S. Ashhurst, Colin J. Jackson, Mithun C. Mahawaththa, Kasuni B Ekanayake, Anupriya Aggarwal, Gottfried Otting, Toby Passioura, Stuart Turville, Christoph Nitsche, Mark Larance, Vishnu M. Sasi, Sven Ullrich, Max J. Bedding, Richard J. Payne, Jason Johansen-Leete
Antivirals that specifically target SARS-CoV-2 are needed to control the COVID-19 pandemic. The main protease (Mpro) is essential for SARS-CoV-2 replication and is an attractive target for antiviral development. Here we report the use of the Random n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b11c7e55951f3e1a3dfdaa05222defab
https://hdl.handle.net/2123/26145
https://hdl.handle.net/2123/26145