Extracellular Vesicle cystatin c is associated with unstable angina in troponin negative patients with acute chest pain.

Autor: Mirthe Dekker, Farahnaz Waissi, Joelle van Bennekom, Max J M Silvis, Nathalie Timmerman, Arjan H Schoneveld, Diederick E Grobbee, Robbert J de Winter, Arend Mosterd, Leo Timmers, Dominique P V de Kleijn

Publikováno v: PLoS ONE, Vol 15, Iss 8, p e0237036 (2020)

BackgroundDespite the use of high-sensitive cardiac troponin there remains a group of high-sensitive cardiac troponin negative patients with unstable angina with a non-neglectable risk for future adverse cardiovascular events, emphasising the need fo

Externí odkaz: https://doaj.org/article/383929d67bbf4807b02097add5e6b0d9

The Effect of Years-Long Exposure to Low-Dose Colchicine on Renal and Liver Function and Blood Creatine Kinase Levels: Safety Insights from the Low-Dose Colchicine 2 (LoDoCo2) Trial

Autor: Amber van Broekhoven, Niekbachsh Mohammadnia, Max J. M. Silvis, Jonathan Los, Aernoud T. L. Fiolet, Tjerk S. J. Opstal, Arend Mosterd, John W. Eikelboom, Stefan M. Nidorf, Charley A. Budgeon, Elizabeth Byrnes, Willem A. Bax, Jan G. P. Tijssen, Dominique P. V. de Kleijn, Peter L. Thompson, Saloua El Messaoudi, Jan H. Cornel

Publikováno v: Clinical drug investigation, 42(11), 977-985. Adis International Ltd
Clinical Drug Investigation, 42, 977-985
Clinical Drug Investigation, 42, 11, pp. 977-985

Contains fulltext : 288089.pdf (Publisher’s version ) (Open Access) BACKGROUND AND OBJECTIVE: The Low-Dose Colchicine-2 (LoDoCo2) trial showed that 2-4 years exposure to colchicine 0.5 mg once daily reduced the risk of cardiovascular events in pati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a7e75f557f8750b00f611a1192bac17
https://research.vumc.nl/en/publications/94450c2a-4c60-47b0-a72e-c9b9f640b416

Safety and efficacy of coronary sinus narrowing in chronic refractory angina: Insights from the RESOURCE study

Autor: Arif A Khokhar, Carlo Zivelonghi, Mirthe Dekker, Geert E. Leenders, Roberto Ferrari, F Sgura, Stefan Verheye, Giuseppe Tarantini, Alessandro Cafaro, Jan-Peter van Kuijk, Stefano Guarracini, Christoph Liebetrau, Maayan Konigstein, Sergio Berti, Dan Ioanes, Matjaž Bunc, Pieter R. Stella, Leo Timmers, Issameddine Ajmi, Antonio Colombo, Shmuel Banai, Ranil de Silva, Francesco Ponticelli, Pierfrancesco Agostoni, Claudio Rapezzi, Max J. M. Silvis, Alfonso Ielasi, Matteo Tebaldi, M. Ciardetti, Jan Sebastian Wolter, Michele Di Mauro, Kevin Cheng, Gianluca Campo, Simon Redwood, Guglielmo Gallone, Francesco Giannini, Tiffany Patterson, Federico De Marco, Gianpiero D'Amico, Steffen Schnupp, Steven Lindsay

Publikováno v: International Journal of Cardiology. 337:29-37

Introduction Refractory angina (RA) is considered the end-stage of coronary artery disease, and often has no interventional treatment options. Coronary sinus Reducer (CSR) is a recent addition to the therapeutic arsenal, but its efficacy has only bee

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2028cf7a18200abd6a68e2e3714b57ee
https://doi.org/10.1016/j.ijcard.2021.05.034

Experimental parameters and infarct size in closed chest pig LAD ischemia reperfusion models; lessons learned

Autor: Dominique P.V. de Kleijn, Max J. M. Silvis, Aernoud T L Fiolet, Lena Bosch, Joyce Mj Visser, Leo Timmers, Mirthe Dekker, Marlijn S Jansen, Martijn M. J. van Nieuwburg, Gerardus P.J. van Hout

Publikováno v: BMC Cardiovascular Disorders, Vol 21, Iss 1, Pp 1-9 (2021)
BMC Cardiovascular Disorders

Background Preclinical models that resemble the clinical setting as closely as possible are essential in translating promising therapies for the treatment of acute myocardial infarction. Closed chest pig left anterior descending coronary artery (LAD)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::521b32b3f537d3ffd4607653ff5f50ee
https://doaj.org/article/48f72536db684e9796a4b598d6cc069d

High levels of osteoprotegerin are associated with coronary artery calcification in patients suspected of a chronic coronary syndrome

Autor: Arjan H. Schoneveld, Nikolas Lessmann, Farahnaz Waissi, Max J. M. Silvis, Robbert J. de Winter, Mirthe Dekker, Joelle van Bennekom, Ivana Išgum, Arend Mosterd, Leo Timmers, Dominique P.V. de Kleijn, B. K. Velthuis, Gerard Pasterkamp

Publikováno v: Scientific reports, 11(1):18946. Nature Publishing Group
Scientific Reports, 11
Scientific Reports
Scientific Reports, 11, 1
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports, 11:18946. Nature Publishing Group

Plasma osteoprotegerin (OPG) and vascular smooth muscle cell (VSMC) derived extracellular vesicles (EVs) are important regulators in the process of vascular calcification (VC). In population studies, high levels of OPG are associated with events. In

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2184ef900cfc9d4b64121b911e993be9
https://pure.amc.nl/en/publications/high-levels-of-osteoprotegerin-are-associated-with-coronary-artery-calcification-in-patients-suspected-of-a-chronic-coronary-syndrome(6a31fa57-b672-46d7-a52b-150902aa240c).html