Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Max Hoek"'
Autor:
Eva Maria Stork, Danique M. H. van Rijswijck, Karin A. van Schie, Max Hoek, Theresa Kissel, Hans Ulrich Scherer, Tom W. J. Huizinga, Albert J. R. Heck, Rene E. M. Toes, Albert Bondt
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract The presence of autoantibodies is a defining feature of many autoimmune diseases. The number of unique autoantibody clones is conceivably limited by immune tolerance mechanisms, but unknown due to limitations of the currently applied technol
Externí odkaz:
https://doaj.org/article/e6689c79691043a1a6804fa22db7f6ee
Autor:
Sebastiaan C. de Graaf, Albert Bondt, Danique M. H. van Rijswijck, Hannah G. Juncker, Sien J. Mulleners, Mirjam J. A. Damen, Max Hoek, Britt J. van Keulen, Johannes B. van Goudoever, Albert J. R. Heck, Kelly A. Dingess
Publikováno v:
Frontiers in Nutrition, Vol 10 (2024)
IntroductionUpon vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) humans will start to produce antibodies targeting virus specific antigens that will end up in circulation. In lactating women such antibodies will also
Externí odkaz:
https://doaj.org/article/5e96a5bf2be6463bb05b7f835f7fbe78
Autor:
Danique M. H. van Rijswijck, Albert Bondt, Max Hoek, Karlijn van der Straten, Tom G. Caniels, Meliawati Poniman, Dirk Eggink, Chantal Reusken, Godelieve J. de Bree, Rogier W. Sanders, Marit J. van Gils, Albert J. R. Heck
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Profiling antibody repertoires using proteomic approaches may provide a way of screening for antibody cross-reactivity against SARS-CoV-2 variants. Here the authors use a IgG1 specific cleavage method to analyse the IgG1 repertoire within recovered p
Externí odkaz:
https://doaj.org/article/eeaed92f1ab84dfd938e3ee685a8d51e
Publikováno v:
mAbs, Vol 14, Iss 1 (2022)
A key step in therapeutic and endogenous humoral antibody characterization is identifying the amino acid sequence. So far, this task has been mainly tackled through sequencing of B-cell receptor (BCR) repertoires at the nucleotide level. Mass spectro
Externí odkaz:
https://doaj.org/article/6f458b33946145028a8ae0809804d460
Autor:
Shelley Jager, Dario A. T. Cramer, Max Hoek, Nadia J. Mokiem, Britt J. van Keulen, Johannes B. van Goudoever, Kelly A. Dingess, Albert J. R. Heck
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
The Alpha-1-Antitrypsin (A1AT) protein is an important protease inhibitor highly abundant in human serum and other body fluids. Additional to functioning as a protease inhibitor, A1AT is an important acute phase protein. Here, we set out to compare t
Externí odkaz:
https://doaj.org/article/eac9078a57cc4527ad8cbb751de6c973
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Recently, a mass spectrometry-based approach was introduced to directly assess the IgG1 immunoglobulin clonal repertoires in plasma. Here we expanded upon this approach by describing a mass spectrometry-based technique to assess specifically the clon
Externí odkaz:
https://doaj.org/article/abe59001fd1e4bbb93a25e37c59bf0dd
Autor:
Matthias Filez, Chiara Caratelli, Miguel Rivera-Torrente, Francesco Muniz-Miranda, Max Hoek, Maarten Altelaar, Albert J.R. Heck, Veronique Van Speybroeck, Bert M. Weckhuysen
Publikováno v:
Cell Reports Physical Science, Vol 2, Iss 12, Pp 100680- (2021)
Summary: Metal-organic framework (MOF) crystallization is governed by molecular assembly processes in the pre-nucleation stage. Yet, unravelling these pre-nucleation pathways and rationalizing their impact on crystal formation poses a great challenge
Externí odkaz:
https://doaj.org/article/4622c604adb54e97a8a9121256cedc23
Autor:
Britt J. van Keulen, Michelle Romijn, Albert Bondt, Kelly A. Dingess, Eva Kontopodi, Karlijn van der Straten, Maurits A. den Boer, Judith A. Burger, Meliawati Poniman, Berend J. Bosch, Philip J. M. Brouwer, Christianne J. M. de Groot, Max Hoek, Wentao Li, Dasja Pajkrt, Rogier W. Sanders, Anne Schoonderwoerd, Sem Tamara, Rian A. H. Timmermans, Gestur Vidarsson, Koert J. Stittelaar, Theo T. Rispens, Kasper A. Hettinga, Marit J. van Gils, Albert J. R. Heck, Johannes B. van Goudoever
Publikováno v:
Nutrients, Vol 13, Iss 5, p 1645 (2021)
Background: Since the outbreak of coronavirus disease 2019 (COVID-19), many put their hopes in the rapid availability of effective immunizations. Human milk, containing antibodies against syndrome coronavirus 2 (SARS-CoV-2), may serve as means of pro
Externí odkaz:
https://doaj.org/article/dc97c9ce34634616a60822bfd93ee76e
Autor:
Albert Bondt, Max Hoek, Kelly Dingess, Sem Tamara, Bastiaan de Graaf, Weiwei Peng, Maurits A. den Boer, Mirjam Damen, Ceri Zwart, Arjan Barendregt, Danique M.H. van Rijswijck, Marloes Grobben, Khadija Tejjani, Jacqueline van Rijswijk, Franziska Völlmy, Joost Snijder, Francesca Fortini, Alberto Papi, Carlo Alberto Volta, Gianluca Campo, Marco Contoli, Marit J. van Gils, Savino Spadaro, Paola Rizzo, Albert J.R. Heck
Here, by using mass spectrometry-based methods IgG1 and IgA1 clonal repertoires were monitored quantitatively and longitudinally in more than 50 individual serum samples obtained from 17 COVID-19 patients admitted to intensive care units because of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfef1e63bb3e3489cc505c6c8f998d83
https://doi.org/10.1101/2022.12.23.22283896
https://doi.org/10.1101/2022.12.23.22283896
Autor:
Kelly A, Dingess, Max, Hoek, Danique M H, van Rijswijk, Sem, Tamara, Maurits A, den Boer, Tim, Veth, Mirjam J A, Damen, Arjan, Barendregt, Michelle, Romijn, Hannah G, Juncker, Britt J, van Keulen, Gestur, Vidarsson, Johannes B, van Goudoever, Albert, Bondt, Albert J R, Heck
Publikováno v:
Cellularmolecular immunology. 20(1)
The most abundant immunoglobulin present in the human body is IgA. It has the highest concentrations at the mucosal lining and in biofluids such as milk and is the second most abundant class of antibodies in serum. We assessed the structural diversit