Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Max H. Rich"'
Autor:
Kyeonggon Shin, Hyunjoon Kong, Bumsoo Han, Dong Hyun Kim, Altug Ozcelikkale, Min Kyung Lee, Nicholas E. Clay, Max H. Rich
Publikováno v:
ACS biomaterials scienceengineering. 2(11)
In the past several decades, significant efforts have been devoted to recapitulating the in vivo tissue microenvironment within an in vitro platform. However, it is still challenging to recreate de novo tissue with physiologically relevant matrix pro
Autor:
Hyunjoon Kong, Ellen C. Qin, Dong Hyun Kim, Min Kyung Lee, Max H. Rich, Deborah E. Leckband, Kwan Young Lee, Hee Jung Chung, C M L Johana Vega
Publikováno v:
Journal of Materials Chemistry B. 4:6803-6811
Living cells are being extensively studied to build functional tissues that are useful for both fundamental and applied bioscience studies. Increasing evidence suggests that cell–cell adhesion controlled by the intercellular cadherin junction plays
Autor:
Hyunjoon Kong, Nicholas E. Clay, Jinrong Chen, Marni D. Boppart, Nicholas M. Marshall, Min Kyung Lee, Ziad S. Mahmassani, Max H. Rich
Publikováno v:
Biomacromolecules. 16:2255-2264
Freeze-dried hydrogels are increasingly used to create 3D interconnected micropores that facilitate biomolecular and cellular transports. However, freeze-drying is often plagued by variance in micropore architecture based on polymer choice. We hypoth
Publikováno v:
Biomacromolecules. 18(8)
For the past few decades, efforts have been extensively made to reproduce tissue of interests for various uses including fundamental bioscience studies, clinical treatments, and even soft robotic systems. In these studies, cells are often cultured in
Publikováno v:
Microsystems & Nanoengineering. 3
A complex and functional living cellular system requires the interaction of one or more cell types to perform specific tasks, such as sensing, processing, or force production. Modular and flexible platforms for fabrication of such multi-cellular modu
Autor:
Hyunjoon Kong, Rashid Bashir, Dong Hyun Kim, Max H. Rich, Larry J. Millet, Jae Hyun Jeong, Min Kyung Lee, Kwanghyun Baek
Publikováno v:
Journal of Controlled Release. 196:363-369
Hydrogels designed to sustainably release bioactive molecules are extensively used to enhance tissue repair and regenerative therapies. Along this line, numerous efforts are made to control the molecular release rate and amount. In contrast, few effo
Autor:
Hyunjoon Kong, Max H. Rich, Mei Hsiu Lai, Artem Shkumatov, Kwanghyun Baek, Nicholas E. Clay, Cartney E. Smith
Publikováno v:
ACS Applied Materials & Interfaces. 5:10266-10273
This study presents a strategy to enhance the uptake of superparamagnetic iron oxide nanoparticle (SPIO) clusters by manipulating the cellular mechanical environment. Specifically, stem cells exposed to an orbital flow ingested almost a 2-fold greate
Publikováno v:
Biomaterials. 58
Bioactive hydrogels have been extensively studied as a platform for 3D cell culture and tissue regeneration. One of the key desired design parameters is the ability to control spatial organization of biomolecules and cells and subsequent tissue in a
Publikováno v:
SCIENTIFIC REPORTS(5)
Scientific Reports
Scientific Reports
Hydrogels are being extensively used for three-dimensional immobilization and culture of cells in fundamental biological studies, biochemical processes and clinical treatments. However, it is still a challenge to support viability and regulate phenot
Autor:
Min Kyung Lee, Kathryn Michele Sullivan, Mei Hsiu Lai, Bumsoo Han, Hojeong Jeon, Nicholas E. Clay, Yen Wah Tong, Altug Ozcelikkale, Jiayu Leong, Youyun Liang, Hyunjoon Kong, Max H. Rich
Publikováno v:
Macromolecular Bioscience. 17:1700117
The progression of cancer is often accompanied by changes in the mechanical properties of an extracellular matrix. However, limited efforts have been made to reproduce these biological events in vitro. To this end, this study demonstrates that matrix