Single-cell imaging of ERK and Akt activation dynamics and heterogeneity induced by G-protein-coupled receptors

Autor: Sergei Chavez-Abiega, Theodorus Gadella, Joachim Goedhart, Max Grönloh, Frank Bruggeman

Publikováno v: Chavez-Abiega, S, Gönloh, M L B, Gadella, T W J, Bruggeman, F J & Goedhart, J 2022, ' Single-cell imaging of ERK and Akt activation dynamics and heterogeneity induced by G-protein-coupled receptors ', Journal of cell science, vol. 135, no. 6, jcs259685, pp. 1-13 . https://doi.org/10.1242/jcs.259685
Journal of Cell Science, 135(6):259685. Company of Biologists Ltd
Journal of cell science, 135(6):jcs259685, 1-13. Company of Biologists Ltd

Kinases play key roles in signaling networks that are activated by G-protein-coupled receptors (GPCRs). Kinase activities are generally inferred from cell lysates, hiding cell-to-cell variability. To study the dynamics and heterogeneity of ERK and Ak

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https://research.vu.nl/en/publications/985f5782-d73c-48bc-9d17-32879f6c3ec4