Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Max Gassman"'
Autor:
Weiqin Yin, Praveen Kumar Rajvanshi, Heather M. Rogers, Teruhiko Yoshida, Jeffrey B. Kopp, Xiuli An, Max Gassmann, Constance T. Noguchi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Erythropoietin (EPO) plays a key role in energy metabolism, with EPO receptor (EpoR) expression in white adipose tissue (WAT) mediating its metabolic activity. Here, we show that male mice lacking EpoR in adipose tissue exhibit increased fat
Externí odkaz:
https://doaj.org/article/e97bfac0edc345d1ab726c7a230f401b
Autor:
Paola Muttathukunnel, Michael Wälti, Mostafa A. Aboouf, Christina Köster-Hegmann, Tatjana Haenggi, Max Gassmann, Patrizia Pannzanelli, Jean-Marc Fritschy, Edith M. Schneider Gasser
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-22 (2023)
Abstract Myelination is a process tightly regulated by a variety of neurotrophic factors. Here, we show—by analyzing two transgenic mouse lines, one overexpressing EPO selectively in the brain Tg21(PDGFB-rhEPO) and another with targeted removal of
Externí odkaz:
https://doaj.org/article/f320bbf9181d4753a439410ef1ff3a6e
Autor:
Rana A. Youness, Hossam A. Hassan, Tasneem Abaza, Ahmed A. Hady, Hekmat M. El Magdoub, Mohamed Ali, Johannes Vogel, Markus Thiersch, Max Gassmann, Nadia M. Hamdy, Mostafa A. Aboouf
Publikováno v:
Cells, Vol 13, Iss 15, p 1245 (2024)
Circular RNAs (circRNAs) are cardinal players in numerous physiological and pathological processes. CircRNAs play dual roles as tumor suppressors and oncogenes in different oncological contexts, including hepatocellular carcinoma (HCC). Their roles s
Externí odkaz:
https://doaj.org/article/bf9cdc23f9074828a9909ce4da9bda2d
Autor:
Mostafa A. Aboouf, Cora S. Thiel, Sergey M. Borisov, Svantje Tauber, Eva Bönzli, Nelli Schetle, Oliver Ullrich, Max Gassmann, Johannes Vogel
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Extravehicular activities, the backbone of manned space exploration programs, set astronauts into mild hypoxia. Unfortunately, microgravity aggravates threatening symptoms of hypoxia such as vision impairment and brain edema. Hypoxia-inducib
Externí odkaz:
https://doaj.org/article/786a0756c1da40b0a6d0311f3b0be605
Autor:
Mostafa A. Aboouf, Julia Armbruster, Franco Guscetti, Markus Thiersch, Andreas Boss, Axel Gödecke, Sandra Winning, Claudia Padberg, Joachim Fandrey, Glen Kristiansen, Anne Bicker, Thomas Hankeln, Max Gassmann, Thomas A. Gorr
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract Myoglobin (MB) is expressed in different cancer types and may act as a tumor suppressor in breast cancer. The mechanisms by which basal MB expression level impacts murine mammary tumorigenesis are unclear. We investigated how MB expression i
Externí odkaz:
https://doaj.org/article/2ea2274e1f1e419e9d74aaf7e0ba4faa
Publikováno v:
HemaSphere, Vol 7, p e032586a (2023)
Externí odkaz:
https://doaj.org/article/7b25b9855e2645df91eabbc364c9972a
Autor:
Aurelia C. Leimbacher, Philipp Villiger, Nina Desboeufs, Mostafa A. Aboouf, Monica Nanni, Julia Armbruster, Hyrije Ademi, Pascal Flüchter, Maja Ruetten, Felix Gantenbein, Thomas J. Haider, Max Gassmann, Markus Thiersch
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107298- (2023)
Summary: Physical exercise can lower lung cancer incidence. However, its effect on lung cancer progression is less understood. Studies on exercising mice have shown decreased ectopic lung cancer growth through the secretion of interleukin-6 from musc
Externí odkaz:
https://doaj.org/article/a7e8c4e255d3400fba32808a850b603d
Autor:
Heimo Mairbäurl, Samuel Kilian, Svenja Seide, Martina U. Muckenthaler, Max Gassmann, Rukundo K. Benedict
Publikováno v:
HemaSphere, Vol 7, Iss 4, p e854 (2023)
To compensate for decreased oxygen partial pressure, high-altitude residents increase hemoglobin concentrations [Hb]. The elevation varies between world regions, posing problems in defining cutoff values for anemia or polycythemia. The currently used
Externí odkaz:
https://doaj.org/article/6c34f2ca847846e8bf88275ec793b672
Autor:
Julia Baumann, Chih-Chieh Tsao, Shalmali Patkar, Sheng-Fu Huang, Simona Francia, Synnøve Norvoll Magnussen, Max Gassmann, Johannes Vogel, Christina Köster-Hegmann, Omolara O. Ogunshola
Publikováno v:
Fluids and Barriers of the CNS, Vol 19, Iss 1, Pp 1-17 (2022)
Abstract Background Ways to prevent disease-induced vascular modifications that accelerate brain damage remain largely elusive. Improved understanding of perivascular cell signalling could provide unparalleled insight as these cells impact vascular s
Externí odkaz:
https://doaj.org/article/fd3c75ae2fe44f24924b6141781a5127
Autor:
Oliver Ullrich, Christian Paul Casal, Natalie Dové, Calista Fischer, Max Gassmann, Martin Daniel Gerber, Rudolf Guldener, Liliana Elisabeth Layer, Bruno Neininger, Silvia Ulrich, Marc Studer, Cora Sandra Thiel
Publikováno v:
Aerospace, Vol 10, Iss 10, p 860 (2023)
Parabolic flights are one of the most important pillars for research, development, and applications in space. Accordingly, we developed the world’s first non-governmental parabolic flight program using Novespace’s Airbus A310 ZERO-G. Through the
Externí odkaz:
https://doaj.org/article/8e157fe8b1794f6f9fd8cb336c727141