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Autor:
Mrinal K. Bera, Reinhold Zimmer, Max Gart, Stefan Leisering, Luise Schefzig, Giaime Rancan, Timon Kurzawa, Hans-Ulrich Reissig, Igor Linder
Publikováno v:
Synthesis. 53:2067-2080
The LANCA three-component reaction of lithiated alkoxyallenes (LA), nitriles (N), and carboxylic acids (CA) smoothly provides β-alkoxy-β-ketoenamides in broad structural variety. The subsequent cyclocondensation of these compounds with hydroxylam