Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Max Flöttmann"'
Publikováno v:
Heliyon, Vol 9, Iss 2, Pp e13101- (2023)
Translation is a central step in gene expression, however its quantitative and time-resolved regulation is poorly understood. We developed a discrete, stochastic model for protein translation in S. cerevisiae in a whole-transcriptome, single-cell con
Externí odkaz:
https://doaj.org/article/9f05300fef98443193dc76c8727465bb
Autor:
Max Schelker, Caroline Maria Mair, Fabian Jolmes, Robert-William Welke, Edda Klipp, Andreas Herrmann, Max Flöttmann, Christian Sieben
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 10, p e1005075 (2016)
After endocytic uptake, influenza viruses transit early endosomal compartments and eventually reach late endosomes. There, the viral glycoprotein hemagglutinin (HA) triggers fusion between endosomal and viral membrane, a critical step that leads to r
Externí odkaz:
https://doaj.org/article/602d7560243d42a5afa2d5686a9516bf
Autor:
Susann Kummer, Max Flöttmann, Björn Schwanhäusser, Christian Sieben, Michael Veit, Matthias Selbach, Edda Klipp, Andreas Herrmann
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94257 (2014)
We studied the dynamics of the proteome of influenza virus A/PR/8/34 (H1N1) infected Madin-Darby canine kidney cells up to 12 hours post infection by mass spectrometry based quantitative proteomics using the approach of stable isotope labeling by ami
Externí odkaz:
https://doaj.org/article/6757120994594bd7b24d1878078e0513
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e14791 (2011)
In systems biology uncertainty about biological processes translates into alternative mathematical model candidates. Here, the goal is to generate, fit and discriminate several candidate models that represent different hypotheses for feedback mechani
Externí odkaz:
https://doaj.org/article/d2fc6688172449b78dcb94758fde5722
Autor:
Nancy Mah, Ying Wang, Mei-Chih Liao, Alessandro Prigione, Justyna Jozefczuk, Björn Lichtner, Katharina Wolfrum, Manuela Haltmeier, Max Flöttmann, Martin Schaefer, Alexander Hahn, Ralf Mrowka, Edda Klipp, Miguel A Andrade-Navarro, James Adjaye
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e24351 (2011)
Somatic cells can be reprogrammed to induced pluripotent stem cells by over-expression of OCT4, SOX2, KLF4 and c-MYC (OSKM). With the aim of unveiling the early mechanisms underlying the induction of pluripotency, we have analyzed transcriptional pro
Externí odkaz:
https://doaj.org/article/6f327d3667594fcfaf6742fcb40f8a79
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Oscillating gene expression is crucial for correct timing and progression through cell cycle. In Saccharomyces cerevisiae, G1 cyclins Cln1–3 are essential drivers of the cell cycle and have an important role for temporal fine-tuning. We measured ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a5fd2fc70eadbd0531ef97f1e480891
https://doi.org/10.1038/s41598-019-39850-7
https://doi.org/10.1038/s41598-019-39850-7
Roles of G1 cyclins in the temporal organization of yeast cell cycle - a transcriptome-wide analysis
Oscillating gene expression is crucial for correct timing and progression through cell cycle. In Saccharomyces cerevisiae, G1 cyclins Cln1-3 are essential drivers of the cell cycle and have an important role for temporal fine-tuning. We measured time
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81d766e7d2632be1664e6e7dc1c832a4
Autor:
Andreas Herrmann, Max Flöttmann, Christian Sieben, Edda Klipp, Fabian Jolmes, Max Schelker, Robert-William Welke, Caroline M. Mair
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 10, p e1005075 (2016)
PLoS Computational Biology
PLoS Computational Biology
After endocytic uptake, influenza viruses transit early endosomal compartments and eventually reach late endosomes. There, the viral glycoprotein hemagglutinin (HA) triggers fusion between endosomal and viral membrane, a critical step that leads to r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbf8ecb3cbe8edbefb54f4de855208d2
http://europepmc.org/articles/PMC5079570?pdf=render
http://europepmc.org/articles/PMC5079570?pdf=render
Publikováno v:
BMC Systems Biology
Background: Cellular decision-making is governed by molecular networks that are highly complex. An integrative understanding of these networks on a genome wide level is essential to understand cellular health and disease. In most cases however, such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ea57217628157cb06d4167f64bbed56
http://hdl.handle.net/2433/210427
http://hdl.handle.net/2433/210427
Autor:
Michael Veit, Andreas Herrmann, Max Flöttmann, Susann Kummer, Björn Schwanhäusser, Matthias Selbach, Edda Klipp, Christian Sieben
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 4, p e94257 (2014)
PLoS ONE, Vol 9, Iss 4, p e94257 (2014)
We studied the dynamics of the proteome of influenza virus A/PR/8/34 (H1N1) infected Madin-Darby canine kidney cells up to 12 hours post infection by mass spectrometry based quantitative proteomics using the approach of stable isotope labeling by ami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a18f11ad9f6466efeea14252aa58f596
http://europepmc.org/articles/PMC3981805
http://europepmc.org/articles/PMC3981805